[Hub]/) : Traits : Neuroticism :

chr20:32,594,714-34,109,427

Best TWAS P=1.31e-08 · Best GWAS P=1.3e-06 conditioned to 0.955

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum NCOA6 0.11 0.10 lasso 10 0.10 4.5e-06 4.7 5.1 2.9e-07 0.92 0.08 0.86 FALSE
2 GTEx Artery Coronary NCOA6 0.20 0.15 enet 27 0.24 1.1e-08 -3.6 5.1 4.2e-07 0.78 0.06 0.90 FALSE
3 GTEx Brain Cortex NCOA6 0.14 0.03 enet 13 0.05 1.6e-02 -3.6 5.1 3.0e-07 0.75 0.05 0.51 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia NCOA6 0.24 0.01 lasso 12 0.08 3.2e-03 -3.6 5.1 2.7e-07 0.65 0.06 0.67 FALSE
5 GTEx Colon Transverse NCOA6 0.10 0.06 lasso 8 0.04 4.1e-03 4.8 5.2 1.7e-07 0.96 0.03 0.90 FALSE
6 GTEx Esophagus Gastroesophageal Junction NCOA6 0.24 0.07 lasso 4 0.08 5.9e-04 4.8 5.3 1.4e-07 0.88 0.04 0.87 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic NCOA6 0.13 0.03 enet 12 0.03 1.5e-02 4.8 5.2 2.5e-07 0.71 0.04 0.81 FALSE
8 ROSMAP Brain Pre-frontal Cortex NCOA6 0.07 0.08 blup 365 0.09 1.9e-11 -3.6 5.1 4.0e-07 0.68 0.49 0.26 FALSE
9 TCGA Breast Normal TP53INP2 0.01 0.00 blup 319 0.01 2.5e-03 4.7 -5.7 1.3e-08 -0.85 0.04 0.80 TRUE