[Hub]/) : Traits : Neuroticism :

chr20:43,958,786-45,456,440

Best TWAS P=6.05e-10 · Best GWAS P=1.28e-09 conditioned to 0.0298

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial CD40 0.13 0.01 lasso 5 0.02 1.4e-02 5.1 -5.6 2.6e-08 -0.80 0.02 0.94 FALSE
2 GTEx Skin Sun Exposed Lower leg CD40 0.13 0.08 lasso 3 0.08 4.1e-07 -5.0 -5.5 3.9e-08 -0.40 0.34 0.64 FALSE
3 METSIM Adipose CD40 0.07 0.04 lasso 4 0.05 3.5e-08 5.3 -6.2 6.0e-10 -0.75 0.04 0.96 TRUE
4 ROSMAP Brain Pre-frontal Cortex SLC12A5 0.24 0.24 lasso 6 0.24 5.4e-30 6.1 6.0 2.3e-09 0.98 0.00 1.00 FALSE
5 TCGA Breast Normal CD40 0.05 0.01 bslmm 485 0.01 4.5e-04 5.3 -5.6 2.0e-08 -0.60 0.09 0.42 FALSE