[Hub]/) : Traits : Neuroticism :

chr22:40,472,399-42,614,362

Best TWAS P=6.81e-10 · Best GWAS P=1.11e-10 conditioned to 0.0538

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts SLC25A17 0.09 0.03 enet 10 0.06 4.2e-05 6.1 6.0 1.9e-09 0.84 0.02 0.98 FALSE
2 GTEx Esophagus Mucosa RANGAP1 0.07 0.02 lasso 4 0.02 8.6e-03 6.2 -6.2 6.8e-10 -0.93 0.02 0.93 TRUE
3 GTEx Nerve Tibial ACO2 0.06 0.05 lasso 5 0.04 8.5e-04 4.6 5.7 1.5e-08 0.80 0.58 0.34 FALSE
4 GTEx Pituitary L3MBTL2 0.19 0.15 enet 17 0.19 1.6e-05 -5.6 5.5 3.2e-08 0.68 0.18 0.57 FALSE
5 YFS Blood TEF 0.09 0.17 lasso 2 0.17 9.0e-53 5.1 5.1 3.2e-07 0.79 0.90 0.10 FALSE