Best TWAS P=2.82e-08 · Best GWAS P=6.76e-09 conditioned to 0.000494
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FRMD4A | 0.11 | 0.04 | lasso | 6 | 0.02 | 1.7e-03 | -5.1 | 5.2 | 2.5e-07 | -0.40 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Brain Cerebellum | RP11-295P9.3 | 0.45 | 0.31 | enet | 25 | 0.36 | 2.4e-11 | 4.0 | -5.3 | 1.1e-07 | 0.45 | 0.69 | 0.28 | TRUE |
| 3 | YFS | Blood | BEND7 | 0.09 | 0.03 | lasso | 10 | 0.08 | 1.4e-25 | 4.7 | -5.2 | 2.0e-07 | 0.59 | 0.40 | 0.59 | FALSE |
| 4 | YFS | Blood | OPTN | 0.29 | 0.20 | lasso | 6 | 0.20 | 2.9e-63 | -5.4 | 5.5 | 2.8e-08 | -0.05 | 0.01 | 0.99 | TRUE |