Best TWAS P=1.34e-10 · Best GWAS P=9.1e-09 conditioned to 0.000253
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | THOC7 | 0.10 | 0.10 | lasso | 5 | 0.06 | 2.7e-08 | 5.5 | -5.4 | 5.4e-08 | -0.39 | 0.01 | 0.99 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | THOC7 | 0.18 | 0.15 | bslmm | 599 | 0.16 | 2.1e-20 | 5.5 | -6.4 | 1.6e-10 | -0.45 | 0.01 | 0.99 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ATXN7 | 0.09 | 0.06 | lasso | 9 | 0.07 | 2.2e-09 | 3.6 | -5.3 | 1.2e-07 | -0.70 | 0.19 | 0.80 | FALSE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | THOC7 | 0.17 | -0.01 | blup | 36 | 0.04 | 2.9e-02 | 5.5 | -6.4 | 1.3e-10 | -0.36 | 0.00 | 0.37 | TRUE |