TWAS
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Traits
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Blood White Count
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chr3:63,121,945-64,684,683
Best TWAS P=1.34e-10 · Best GWAS P=9.1e-09 conditioned to 0.000253
63.2M
63.4M
63.6M
63.8M
64M
64.2M
64.4M
64.6M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Skin Cutaneous Melanoma
THOC7
0.17
-0.01
blup
36
0.04
2.9e-02
5.5
-6.4
1.3e-10
-0.36
0.00
0.37
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
THOC7
0.18
0.15
bslmm
599
0.16
2.1e-20
5.5
-6.4
1.6e-10
-0.45
0.01
0.99
FALSE
1
CommonMind
Brain Pre-frontal Cortex
THOC7
0.10
0.10
lasso
5
0.06
2.7e-08
5.5
-5.4
5.4e-08
-0.39
0.01
0.99
FALSE
3
ROSMAP
Brain Pre-frontal Cortex
ATXN7
0.09
0.06
lasso
9
0.07
2.2e-09
3.6
-5.3
1.2e-07
-0.70
0.19
0.80
FALSE