Best TWAS P=2.15e-08 · Best GWAS P=3.81e-08 conditioned to 0.0922
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | TOMM7 | 0.25 | 0.19 | enet | 21 | 0.26 | 2.1e-20 | -4.9 | 5.6 | 2.2e-08 | -0.80 | 0.04 | 0.95 | TRUE |
| 2 | GTEx | Thyroid | AC005682.5 | 0.23 | 0.13 | lasso | 7 | 0.16 | 3.0e-12 | -4.9 | -5.3 | 9.3e-08 | 0.59 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | TOMM7 | 0.15 | 0.09 | blup | 63 | 0.08 | 4.0e-03 | -4.9 | 5.2 | 2.6e-07 | -0.84 | 0.01 | 0.76 | FALSE |