[Hub]/) : Traits : Blood Platelet Count :

chr9:139,045,828-140,706,127

Best TWAS P=2.59e-15 · Best GWAS P=4.86e-14 conditioned to 0.000653

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DPP7 0.18 0.15 lasso 4 0.14 3.4e-16 4.4 5.2 2.1e-07 0.34 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex MAN1B1 0.09 0.06 bslmm 368 0.07 1.0e-08 4.2 5.2 1.7e-07 0.54 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous DPP7 0.15 0.09 lasso 3 0.08 2.0e-07 4.2 5.2 1.6e-07 0.35 1.00 0.00 FALSE
4 GTEx Artery Aorta DPP7 0.09 0.00 lasso 8 0.00 4.6e-01 4.6 6.9 5.0e-12 0.34 0.10 0.10 FALSE
5 GTEx Artery Tibial DPP7 0.20 0.12 lasso 8 0.15 1.4e-11 -6.9 6.7 2.5e-11 0.20 0.35 0.65 FALSE
6 GTEx Brain Cerebellar Hemisphere DPP7 0.31 0.08 lasso 5 0.10 1.4e-03 -6.5 6.4 2.1e-10 0.14 0.11 0.34 FALSE
7 GTEx Cells Transformed fibroblasts AL807752.1 0.18 0.03 lasso 8 0.05 1.6e-04 -6.9 -6.8 8.9e-12 -0.25 0.16 0.83 FALSE
8 GTEx Colon Transverse UAP1L1 0.16 0.10 enet 8 0.13 8.4e-07 -6.3 6.9 6.0e-12 0.16 0.28 0.41 FALSE
9 GTEx Nerve Tibial DPP7 0.20 0.12 enet 14 0.18 9.3e-13 4.3 6.6 3.1e-11 0.29 0.66 0.34 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic PHPT1 0.12 0.02 lasso 4 0.04 3.4e-03 7.5 5.8 5.4e-09 0.88 0.01 0.95 FALSE
11 GTEx Stomach DPP7 0.16 0.06 lasso 4 0.07 3.7e-04 -6.5 6.7 2.8e-11 0.30 0.15 0.59 FALSE
12 GTEx Testis DPP7 0.30 0.26 lasso 7 0.29 2.4e-13 4.3 6.0 2.2e-09 0.35 0.86 0.14 FALSE
13 GTEx Thyroid C8G 0.09 0.01 lasso 4 0.00 2.0e-01 6.5 -5.9 3.3e-09 -0.55 0.11 0.10 FALSE
14 GTEx Uterus DPP7 0.35 -0.01 lasso 7 0.00 3.8e-01 -5.3 5.5 4.7e-08 0.24 0.04 0.09 FALSE
15 METSIM Adipose AL807752.1 0.04 0.00 bslmm 364 0.01 2.2e-03 -5.6 -7.9 2.6e-15 -0.61 0.02 0.94 TRUE
16 The Cancer Genome Atlas Breast Invasive Carcinoma LOC100289341 0.05 0.04 blup 44 0.04 1.6e-09 -6.5 -6.4 1.2e-10 -0.15 0.01 0.99 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma TRAF2 0.01 0.01 blup 48 0.01 1.2e-02 6.6 6.1 1.3e-09 0.78 0.03 0.31 FALSE
18 The Cancer Genome Atlas Colon Adenocarcinoma LOC100289341 0.07 0.03 lasso 3 0.04 2.2e-03 -5.3 -6.0 2.4e-09 -0.17 0.02 0.88 FALSE
19 The Cancer Genome Atlas Esophageal Carcinoma LOC100289341 0.16 0.08 blup 43 0.06 4.3e-03 -7.1 -6.0 1.4e-09 -0.18 0.00 0.95 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma LOC100289341 0.04 0.04 enet 8 0.03 2.5e-04 -6.9 -6.8 9.4e-12 -0.17 0.01 0.98 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC100289341 0.17 0.11 enet 6 0.14 1.8e-15 -5.3 -5.8 5.9e-09 -0.14 0.52 0.48 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PTGDS 0.05 0.01 blup 46 0.03 2.9e-04 3.2 5.7 1.4e-08 0.77 0.33 0.53 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRAF2 0.03 0.01 blup 48 0.02 4.6e-03 2.6 5.5 2.9e-08 0.75 0.04 0.86 FALSE
24 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LOC100289341 0.08 0.03 blup 43 0.07 1.1e-04 -5.7 -5.7 1.4e-08 -0.03 0.01 0.96 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma LOC100289341 0.05 0.06 lasso 1 0.06 5.6e-07 -6.6 -6.6 4.2e-11 -0.17 0.01 0.99 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma MAN1B1 0.03 0.01 blup 48 0.03 6.5e-04 -6.3 6.0 1.9e-09 0.26 0.03 0.70 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma NPDC1 0.04 0.01 blup 38 0.03 4.1e-04 -5.7 5.7 9.9e-09 0.08 0.00 0.93 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma TRAF2 0.02 0.02 lasso 3 0.02 5.6e-03 6.5 6.6 4.2e-11 0.69 0.06 0.38 FALSE
29 The Cancer Genome Atlas Liver Hepatocellular Carcinoma LOC100289341 0.05 0.03 blup 44 0.05 2.2e-03 -6.9 -6.6 4.0e-11 -0.32 0.01 0.90 FALSE
30 The Cancer Genome Atlas Lung Adenocarcinoma DPP7 0.04 0.04 blup 39 0.04 8.7e-06 4.3 6.2 5.0e-10 0.31 0.06 0.93 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma LOC100289341 0.04 0.03 blup 44 0.05 8.9e-07 4.1 -6.5 6.9e-11 -0.33 0.12 0.86 FALSE
32 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LOC100289341 0.12 0.04 lasso 3 0.04 4.7e-05 -5.7 -5.8 9.1e-09 -0.09 0.02 0.97 FALSE
33 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LOC100289341 0.04 0.06 lasso 2 0.04 5.3e-04 -6.5 -6.6 3.8e-11 -0.16 0.01 0.97 FALSE
34 The Cancer Genome Atlas Pancreatic Adenocarcinoma LOC100289341 0.10 0.02 enet 7 0.06 1.2e-03 2.3 -6.1 8.2e-10 -0.27 0.01 0.72 FALSE
35 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PTGDS 0.07 0.06 lasso 7 0.07 1.0e-03 3.1 5.3 1.2e-07 0.80 0.02 0.84 FALSE
36 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TRAF2 0.09 0.06 blup 48 0.09 1.5e-04 7.5 5.3 9.4e-08 0.80 0.01 0.94 FALSE
37 The Cancer Genome Atlas Prostate Adenocarcinoma LOC100289341 0.11 0.12 enet 13 0.14 2.2e-14 -5.7 -6.5 8.3e-11 -0.14 0.04 0.96 FALSE
38 The Cancer Genome Atlas Soft Tissue Sarcoma LOC100289341 0.06 0.04 blup 44 0.04 1.1e-03 -6.9 -7.2 7.5e-13 -0.23 0.01 0.88 FALSE
39 The Cancer Genome Atlas Stomach Adenocarcinoma LOC100289341 0.08 0.06 blup 43 0.08 1.4e-06 4.1 -6.5 6.2e-11 -0.33 0.28 0.68 FALSE
40 The Cancer Genome Atlas Testicular Germ Cell Tumors LOC100289341 0.09 0.07 blup 44 0.10 1.7e-04 -6.9 -6.6 4.9e-11 -0.31 0.01 0.82 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma LOC100289341 0.13 0.19 lasso 2 0.18 1.9e-17 -6.9 -6.9 6.3e-12 -0.17 0.00 1.00 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma TRAF2 0.08 0.02 enet 7 0.04 1.7e-04 3.1 5.2 2.3e-07 0.55 0.24 0.32 FALSE