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chr9:139,045,828-140,706,127

Best TWAS P=2.59e-15 · Best GWAS P=4.86e-14 conditioned to 0.000653

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	METSIM	Adipose	AL807752.1	0.04	0.00	bslmm	364	0.01	2.2e-03	-5.6	-7.9	2.6e-15	-0.61	0.02	0.94	TRUE
38	The Cancer Genome Atlas	Soft Tissue Sarcoma	LOC100289341	0.06	0.04	blup	44	0.04	1.1e-03	-6.9	-7.2	7.5e-13	-0.23	0.01	0.88	FALSE
4	GTEx	Artery Aorta	DPP7	0.09	0.00	lasso	8	0.00	4.6e-01	4.6	6.9	5.0e-12	0.34	0.10	0.10	FALSE
8	GTEx	Colon Transverse	UAP1L1	0.16	0.10	enet	8	0.13	8.4e-07	-6.3	6.9	6.0e-12	0.16	0.28	0.41	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100289341	0.13	0.19	lasso	2	0.18	1.9e-17	-6.9	-6.9	6.3e-12	-0.17	0.00	1.00	FALSE
7	GTEx	Cells Transformed fibroblasts	AL807752.1	0.18	0.03	lasso	8	0.05	1.6e-04	-6.9	-6.8	8.9e-12	-0.25	0.16	0.83	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LOC100289341	0.04	0.04	enet	8	0.03	2.5e-04	-6.9	-6.8	9.4e-12	-0.17	0.01	0.98	FALSE
5	GTEx	Artery Tibial	DPP7	0.20	0.12	lasso	8	0.15	1.4e-11	-6.9	6.7	2.5e-11	0.20	0.35	0.65	FALSE
11	GTEx	Stomach	DPP7	0.16	0.06	lasso	4	0.07	3.7e-04	-6.5	6.7	2.8e-11	0.30	0.15	0.59	FALSE
9	GTEx	Nerve Tibial	DPP7	0.20	0.12	enet	14	0.18	9.3e-13	4.3	6.6	3.1e-11	0.29	0.66	0.34	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC100289341	0.04	0.06	lasso	2	0.04	5.3e-04	-6.5	-6.6	3.8e-11	-0.16	0.01	0.97	FALSE
29	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC100289341	0.05	0.03	blup	44	0.05	2.2e-03	-6.9	-6.6	4.0e-11	-0.32	0.01	0.90	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC100289341	0.05	0.06	lasso	1	0.06	5.6e-07	-6.6	-6.6	4.2e-11	-0.17	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRAF2	0.02	0.02	lasso	3	0.02	5.6e-03	6.5	6.6	4.2e-11	0.69	0.06	0.38	FALSE
40	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LOC100289341	0.09	0.07	blup	44	0.10	1.7e-04	-6.9	-6.6	4.9e-11	-0.31	0.01	0.82	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	LOC100289341	0.08	0.06	blup	43	0.08	1.4e-06	4.1	-6.5	6.2e-11	-0.33	0.28	0.68	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC100289341	0.04	0.03	blup	44	0.05	8.9e-07	4.1	-6.5	6.9e-11	-0.33	0.12	0.86	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC100289341	0.11	0.12	enet	13	0.14	2.2e-14	-5.7	-6.5	8.3e-11	-0.14	0.04	0.96	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC100289341	0.05	0.04	blup	44	0.04	1.6e-09	-6.5	-6.4	1.2e-10	-0.15	0.01	0.99	FALSE
6	GTEx	Brain Cerebellar Hemisphere	DPP7	0.31	0.08	lasso	5	0.10	1.4e-03	-6.5	6.4	2.1e-10	0.14	0.11	0.34	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	DPP7	0.04	0.04	blup	39	0.04	8.7e-06	4.3	6.2	5.0e-10	0.31	0.06	0.93	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC100289341	0.10	0.02	enet	7	0.06	1.2e-03	2.3	-6.1	8.2e-10	-0.27	0.01	0.72	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRAF2	0.01	0.01	blup	48	0.01	1.2e-02	6.6	6.1	1.3e-09	0.78	0.03	0.31	FALSE
19	The Cancer Genome Atlas	Esophageal Carcinoma	LOC100289341	0.16	0.08	blup	43	0.06	4.3e-03	-7.1	-6.0	1.4e-09	-0.18	0.00	0.95	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAN1B1	0.03	0.01	blup	48	0.03	6.5e-04	-6.3	6.0	1.9e-09	0.26	0.03	0.70	FALSE
12	GTEx	Testis	DPP7	0.30	0.26	lasso	7	0.29	2.4e-13	4.3	6.0	2.2e-09	0.35	0.86	0.14	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC100289341	0.07	0.03	lasso	3	0.04	2.2e-03	-5.3	-6.0	2.4e-09	-0.17	0.02	0.88	FALSE
13	GTEx	Thyroid	C8G	0.09	0.01	lasso	4	0.00	2.0e-01	6.5	-5.9	3.3e-09	-0.55	0.11	0.10	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	PHPT1	0.12	0.02	lasso	4	0.04	3.4e-03	7.5	5.8	5.4e-09	0.88	0.01	0.95	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC100289341	0.17	0.11	enet	6	0.14	1.8e-15	-5.3	-5.8	5.9e-09	-0.14	0.52	0.48	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC100289341	0.12	0.04	lasso	3	0.04	4.7e-05	-5.7	-5.8	9.1e-09	-0.09	0.02	0.97	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	NPDC1	0.04	0.01	blup	38	0.03	4.1e-04	-5.7	5.7	9.9e-09	0.08	0.00	0.93	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PTGDS	0.05	0.01	blup	46	0.03	2.9e-04	3.2	5.7	1.4e-08	0.77	0.33	0.53	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOC100289341	0.08	0.03	blup	43	0.07	1.1e-04	-5.7	-5.7	1.4e-08	-0.03	0.01	0.96	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRAF2	0.03	0.01	blup	48	0.02	4.6e-03	2.6	5.5	2.9e-08	0.75	0.04	0.86	FALSE
14	GTEx	Uterus	DPP7	0.35	-0.01	lasso	7	0.00	3.8e-01	-5.3	5.5	4.7e-08	0.24	0.04	0.09	FALSE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TRAF2	0.09	0.06	blup	48	0.09	1.5e-04	7.5	5.3	9.4e-08	0.80	0.01	0.94	FALSE
35	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PTGDS	0.07	0.06	lasso	7	0.07	1.0e-03	3.1	5.3	1.2e-07	0.80	0.02	0.84	FALSE
3	GTEx	Adipose Subcutaneous	DPP7	0.15	0.09	lasso	3	0.08	2.0e-07	4.2	5.2	1.6e-07	0.35	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MAN1B1	0.09	0.06	bslmm	368	0.07	1.0e-08	4.2	5.2	1.7e-07	0.54	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DPP7	0.18	0.15	lasso	4	0.14	3.4e-16	4.4	5.2	2.1e-07	0.34	1.00	0.00	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	TRAF2	0.08	0.02	enet	7	0.04	1.7e-04	3.1	5.2	2.3e-07	0.55	0.24	0.32	FALSE