Best TWAS P=1.25e-12 · Best GWAS P=5.69e-11 conditioned to 2.26e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | PYROXD1 | 0.26 | -0.01 | enet | 24 | -0.01 | 4.7e-01 | -2.8 | -5.7 | 1.0e-08 | -0.09 | 0.09 | 0.08 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | GOLT1B | 0.16 | 0.15 | lasso | 6 | 0.13 | 2.9e-06 | 5.2 | 6.1 | 1.1e-09 | 0.04 | 0.50 | 0.07 | TRUE |
| 3 | NTR | Blood | C12orf39 | 0.03 | 0.02 | lasso | 3 | 0.01 | 2.7e-05 | 5.4 | 5.8 | 9.0e-09 | -0.01 | 0.66 | 0.32 | FALSE |
| 4 | YFS | Blood | GOLT1B | 0.21 | 0.14 | enet | 36 | 0.16 | 3.2e-49 | 4.6 | 7.1 | 1.2e-12 | 0.17 | 0.98 | 0.02 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | C12orf39 | 0.05 | 0.01 | blup | 83 | 0.04 | 1.5e-04 | 4.4 | 5.8 | 4.9e-09 | 0.02 | 0.04 | 0.50 | FALSE |