Best TWAS P=2.55e-09 · Best GWAS P=2.23e-11 conditioned to 0.00211
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | CCDC68 | 0.24 | 0.13 | lasso | 8 | 0.14 | 7.7e-11 | -5.8 | 6.0 | 2.6e-09 | -0.92 | 0.03 | 0.97 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | CCDC68 | 0.05 | 0.01 | enet | 6 | 0.03 | 3.6e-04 | -4.1 | 5.4 | 5.6e-08 | -0.71 | 0.02 | 0.92 | FALSE |