Best TWAS P=4.87e-08 · Best GWAS P=2.26e-10 conditioned to 1.85e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | WRNIP1 | 0.10 | 0.03 | lasso | 4 | 0.04 | 5.6e-06 | 4.9 | -5.4 | 8.1e-08 | -0.03 | 0.08 | 0.88 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MYLK4 | 0.03 | 0.00 | lasso | 4 | 0.02 | 2.6e-04 | -3.3 | 5.5 | 4.9e-08 | 0.01 | 0.01 | 0.93 | TRUE |