TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood Platelet Count
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chr6:2,071,661-3,485,964
Best TWAS P=4.87e-08 · Best GWAS P=2.26e-10 conditioned to 1.85e-10
2M
2.2M
2.4M
2.6M
2.8M
3M
3.2M
3.4M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
MYLK4
0.03
0.00
lasso
4
0.02
2.6e-04
-3.3
5.5
4.9e-08
0.01
0.01
0.93
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
WRNIP1
0.10
0.03
lasso
4
0.04
5.6e-06
4.9
-5.4
8.1e-08
-0.03
0.08
0.88
FALSE