[Hub]/) : Traits : Allergy or Eczema : ← →

chr6:134,905,567-136,516,257

Best TWAS P=2.31e-14 · Best GWAS P=5.73e-16 conditioned to 0.00197

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	AHI1	0.40	0.27	lasso	5	0.34	1.0e-28	3.2	-5.8	7.7e-09	-0.60	1.00	0.00	FALSE
2	GTEx	Artery Tibial	AHI1	0.11	0.03	enet	16	0.09	1.8e-07	6.1	-6.8	9.7e-12	-0.80	0.09	0.90	FALSE
3	GTEx	Brain Cerebellar Hemisphere	AHI1	0.35	0.05	lasso	10	0.15	9.8e-05	3.2	-6.1	9.7e-10	-0.75	0.03	0.93	FALSE
4	GTEx	Brain Cortex	AHI1	0.51	0.27	lasso	6	0.37	3.3e-11	6.0	-6.0	1.6e-09	-0.77	0.36	0.60	FALSE
5	GTEx	Brain Cortex	RP3-388E23.2	0.28	0.16	enet	13	0.19	5.8e-06	3.2	-6.5	1.2e-10	-0.76	0.28	0.47	FALSE
6	GTEx	Brain Hippocampus	AHI1	0.28	0.10	lasso	5	0.05	2.9e-02	5.8	-5.2	2.3e-07	-0.60	0.09	0.27	FALSE
7	GTEx	Breast Mammary Tissue	AHI1	0.34	0.29	lasso	4	0.35	1.1e-18	3.2	-5.5	3.5e-08	-0.57	1.00	0.00	FALSE
8	GTEx	Breast Mammary Tissue (Male)	AHI1	0.19	0.06	lasso	2	0.14	3.2e-04	3.2	-5.8	7.2e-09	-0.63	0.04	0.49	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	AHI1	0.38	0.24	enet	19	0.23	5.4e-08	7.4	-7.2	8.0e-13	-0.83	0.06	0.93	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	RP3-388E23.2	0.26	0.05	lasso	6	0.02	7.1e-02	7.4	-7.4	1.3e-13	-0.90	0.04	0.85	FALSE
11	GTEx	Cells Transformed fibroblasts	AHI1	0.44	0.21	enet	22	0.32	4.4e-24	7.0	-7.0	3.7e-12	-0.75	0.64	0.36	FALSE
12	GTEx	Cells Transformed fibroblasts	RP3-388E23.2	0.13	0.13	lasso	5	0.15	3.5e-11	3.2	-5.4	6.3e-08	-0.61	0.99	0.01	FALSE
13	GTEx	Esophagus Mucosa	AHI1	0.30	0.24	lasso	8	0.32	4.6e-22	7.4	-7.1	1.3e-12	-0.78	0.23	0.77	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	AHI1	0.41	0.31	lasso	7	0.40	9.1e-24	7.3	-7.1	1.3e-12	-0.81	0.14	0.86	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RP3-388E23.2	0.14	0.03	enet	17	0.12	3.7e-07	6.0	-6.1	8.2e-10	-0.74	0.03	0.94	FALSE
16	GTEx	Skin Sun Exposed Lower leg	AHI1	0.33	0.22	enet	14	0.34	1.0e-28	3.2	-6.5	1.1e-10	-0.73	0.89	0.11	FALSE
17	GTEx	Skin Sun Exposed Lower leg	RP3-388E23.2	0.10	0.06	enet	6	0.04	3.1e-04	7.8	-6.6	3.7e-11	-0.85	0.04	0.95	FALSE
18	GTEx	Small Intestine Terminal Ileum	AHI1	0.51	0.01	enet	19	0.06	2.0e-02	7.3	-6.6	4.0e-11	-0.72	0.03	0.60	FALSE
19	GTEx	Spleen	AHI1	0.31	0.21	lasso	3	0.38	8.6e-11	6.0	-7.0	3.3e-12	-0.72	0.10	0.73	FALSE
20	GTEx	Testis	AHI1	0.37	0.32	enet	25	0.37	3.5e-17	7.4	-6.7	2.6e-11	-0.79	0.23	0.77	FALSE
21	GTEx	Testis	RP3-388E23.2	0.23	0.19	lasso	3	0.24	5.7e-11	3.2	-5.9	3.7e-09	-0.63	0.38	0.59	FALSE
22	METSIM	Adipose	AHI1	0.25	0.22	lasso	7	0.28	1.1e-42	7.4	-7.1	1.0e-12	-0.79	0.26	0.74	FALSE
23	NTR	Blood	AHI1	0.11	0.14	lasso	6	0.15	3.2e-47	7.4	-7.3	2.1e-13	-0.78	0.34	0.66	FALSE
24	YFS	Blood	AHI1	0.24	0.30	bslmm	414	0.33	1.4e-110	7.3	-7.3	3.7e-13	-0.80	0.28	0.72	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	AHI1	0.06	0.02	lasso	7	0.02	1.3e-04	7.3	-7.3	2.7e-13	-0.78	0.13	0.86	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf217	0.02	0.02	blup	80	0.02	1.2e-05	6.8	-6.2	6.2e-10	-0.71	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	AHI1	0.06	0.08	blup	73	0.06	1.1e-03	7.3	-6.8	1.3e-11	-0.80	0.04	0.83	FALSE
28	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AHI1	0.18	0.19	lasso	4	0.18	6.4e-20	7.3	-7.5	9.7e-14	-0.82	0.26	0.74	FALSE
29	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AHI1	0.05	0.00	blup	73	0.02	7.1e-04	3.2	-6.4	1.6e-10	-0.66	0.01	0.48	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	AHI1	0.03	0.02	enet	7	0.01	8.1e-03	7.3	-6.5	5.8e-11	-0.80	0.02	0.88	FALSE
31	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AHI1	0.13	0.16	lasso	3	0.16	1.2e-17	7.3	-7.4	1.2e-13	-0.82	0.33	0.67	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf217	0.04	0.03	blup	81	0.01	1.7e-02	7.4	-6.2	4.1e-10	-0.68	0.00	0.98	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AHI1	0.05	0.05	lasso	1	0.04	1.5e-03	7.4	-7.4	1.4e-13	-0.82	0.03	0.72	FALSE
34	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf217	0.06	0.06	enet	9	0.07	1.6e-05	6.1	-6.0	2.7e-09	-0.69	0.16	0.83	FALSE
35	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf217	0.10	0.00	blup	82	0.04	6.8e-03	6.8	-6.0	2.1e-09	-0.66	0.01	0.74	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	AHI1	0.07	0.00	enet	8	0.03	7.5e-04	7.4	-5.6	2.7e-08	-0.74	0.01	0.95	FALSE
37	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AHI1	0.36	0.30	lasso	3	0.29	1.0e-10	7.4	-7.6	2.3e-14	-0.84	0.06	0.94	TRUE