Best TWAS P=7.48e-13 · Best GWAS P=3.1e-15 conditioned to 0.001
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | RP11-467H10.1 | 0.27 | 0.18 | enet | 23 | 0.12 | 6.0e-05 | 2.3 | -5.4 | 8.2e-08 | -0.52 | 0.26 | 0.23 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | GSAP | 0.30 | 0.20 | lasso | 4 | 0.25 | 1.1e-18 | 7.9 | -7.2 | 7.5e-13 | -0.92 | 0.00 | 1.00 | TRUE |
3 | NTR | Blood | FGL2 | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.7e-07 | 4.6 | 5.3 | 1.1e-07 | 0.41 | 0.86 | 0.02 | FALSE |