Best TWAS P=2.5e-10 · Best GWAS P=1.69e-14 conditioned to 3.52e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | PIBF1 | 0.25 | 0.23 | lasso | 3 | 0.21 | 2.1e-06 | -6.0 | 6.3 | 2.5e-10 | -0.50 | 0.59 | 0.10 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | PIBF1 | 0.19 | 0.05 | lasso | 5 | 0.04 | 3.1e-03 | -6.1 | 6.3 | 3.4e-10 | -0.45 | 0.32 | 0.13 | TRUE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | PIBF1 | 0.09 | 0.05 | blup | 96 | 0.08 | 3.4e-06 | -3.8 | 5.8 | 6.1e-09 | -0.29 | 0.06 | 0.89 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PIBF1 | 0.06 | 0.04 | blup | 96 | 0.05 | 5.1e-06 | -3.7 | 5.8 | 7.7e-09 | -0.29 | 0.06 | 0.90 | FALSE |