[Hub]/) : Traits : Age at First Birth : →

chr1:153,220,716-154,640,423

Best TWAS P=7.37e-10 · Best GWAS P=2.55e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	CREB3L4	0.10	0.09	lasso	7	0.11	9.0e-09	-3.8	-5.3	1.1e-07	0.84	0.06	0.94	FALSE
2	GTEx	Cells Transformed fibroblasts	CREB3L4	0.06	0.04	lasso	6	0.03	1.8e-03	-4.8	-5.6	1.9e-08	0.84	0.08	0.91	FALSE
3	GTEx	Colon Transverse	RP11-422P24.10	0.09	0.12	lasso	8	0.08	1.1e-04	-5.7	5.7	1.5e-08	-0.97	0.03	0.96	FALSE
4	GTEx	Muscle Skeletal	CREB3L4	0.03	0.05	lasso	3	0.04	1.4e-04	-5.5	-5.7	9.6e-09	0.96	0.04	0.96	FALSE
5	GTEx	Muscle Skeletal	CRTC2	0.04	0.02	lasso	7	0.01	7.8e-02	-5.4	5.6	2.7e-08	-0.93	0.04	0.95	FALSE
6	GTEx	Muscle Skeletal	RP11-422P24.10	0.03	0.02	enet	7	0.01	1.4e-02	-5.8	5.7	1.3e-08	-0.97	0.03	0.94	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	RP11-422P24.10	0.07	0.08	lasso	2	0.08	6.3e-05	-6.0	5.8	6.5e-09	-0.93	0.03	0.92	FALSE
8	GTEx	Testis	RP11-422P24.10	0.12	0.02	lasso	2	0.03	2.5e-02	-5.7	5.2	1.8e-07	-0.91	0.04	0.80	FALSE
9	GTEx	Thyroid	RP11-422P24.10	0.06	0.00	lasso	3	0.01	8.1e-02	-5.8	5.5	4.3e-08	-0.92	0.03	0.88	FALSE
10	METSIM	Adipose	SLC39A1	0.05	0.02	bslmm	331	0.04	5.6e-07	-5.9	-5.8	9.1e-09	0.75	0.03	0.97	FALSE
11	NTR	Blood	SLC39A1	0.02	0.02	lasso	3	0.02	5.8e-06	-5.4	-5.4	7.0e-08	0.97	0.04	0.96	FALSE
12	YFS	Blood	CRTC2	0.01	0.00	blup	301	0.00	7.6e-02	-5.8	5.3	1.3e-07	-0.88	0.04	0.93	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CREB3L4	0.05	0.02	blup	33	0.03	2.4e-03	-5.8	-5.4	5.9e-08	0.91	0.03	0.79	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP210L	0.02	0.02	blup	72	0.02	5.2e-05	-5.4	-5.7	1.0e-08	0.91	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CREB3L4	0.08	0.07	enet	9	0.08	9.0e-10	-5.7	-5.7	1.2e-08	0.91	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CREB3L4	0.21	0.05	lasso	3	0.05	7.4e-04	-4.3	-5.2	2.4e-07	0.74	0.04	0.52	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	CREB3L4	0.08	0.04	blup	33	0.05	6.6e-07	-4.4	-5.8	5.6e-09	0.83	0.07	0.92	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC39A1	0.02	0.02	blup	35	0.02	2.4e-03	-5.8	-6.0	1.7e-09	0.98	0.02	0.87	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NUP210L	0.04	0.03	enet	15	0.06	1.3e-07	-5.4	-5.3	1.1e-07	0.67	0.06	0.90	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC39A1	0.02	0.02	blup	35	0.01	3.0e-02	-5.9	-6.2	7.4e-10	0.98	0.01	0.70	TRUE
21	The Cancer Genome Atlas	Skin Cutaneous Melanoma	DENND4B	0.10	0.09	enet	2	0.04	2.8e-02	-5.4	-5.5	3.5e-08	0.97	0.01	0.63	FALSE
22	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RAB13	0.13	0.08	blup	30	0.06	1.0e-02	-5.4	-6.1	1.2e-09	0.93	0.02	0.71	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	CREB3L4	0.11	0.11	lasso	3	0.12	6.4e-12	-4.4	-5.5	4.8e-08	0.83	0.05	0.95	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	NUP210L	0.06	0.04	blup	71	0.05	1.5e-05	-5.4	-5.4	5.3e-08	0.88	0.05	0.93	FALSE