TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Bipolar Disorder or Schizophrenia
:
←
→
chr6:83,228,260-84,829,622
Best TWAS P=4.4e-13 · Best GWAS P=3.08e-12 conditioned to 0.402
83.2M
83.4M
83.6M
83.8M
84M
84.2M
84.4M
84.6M
84.8M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
SNAP91
0.13
0.09
lasso
3
0.10
5.8e-05
-6.7
7.2
4.4e-13
-0.92
0.02
0.94
TRUE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
SNAP91
0.04
0.02
blup
101
0.02
5.1e-03
-6.7
6.1
1.0e-09
-0.88
0.02
0.95
FALSE
1
GTEx
Adrenal Gland
ME1
0.12
0.02
lasso
4
0.04
1.7e-02
4.3
-5.4
6.1e-08
0.55
0.10
0.18
FALSE