Best TWAS P=4.4e-13 · Best GWAS P=3.08e-12 conditioned to 0.402
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | ME1 | 0.12 | 0.02 | lasso | 4 | 0.04 | 1.7e-02 | 4.3 | -5.4 | 6.1e-08 | 0.55 | 0.10 | 0.18 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SNAP91 | 0.04 | 0.02 | blup | 101 | 0.02 | 5.1e-03 | -6.7 | 6.1 | 1.0e-09 | -0.88 | 0.02 | 0.95 | FALSE |
3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SNAP91 | 0.13 | 0.09 | lasso | 3 | 0.10 | 5.8e-05 | -6.7 | 7.2 | 4.4e-13 | -0.92 | 0.02 | 0.94 | TRUE |