Best TWAS P=2.87e-08 · Best GWAS P=2.3e-07 conditioned to 0.231
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | DUS2 | 0.19 | 0.14 | enet | 14 | 0.19 | 9.7e-06 | 3.2 | 5.3 | 9.7e-08 | -0.05 | 0.04 | 0.87 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | 0.09 | 0.02 | lasso | 3 | 0.01 | 1.2e-01 | 4.9 | -5.2 | 2.3e-07 | -0.87 | 0.03 | 0.86 | FALSE | |
| 3 | GTEx | Thyroid | TERF2 | 0.12 | 0.12 | lasso | 5 | 0.14 | 1.6e-10 | 5.2 | -5.4 | 5.9e-08 | -0.96 | 0.01 | 0.99 | FALSE |
| 4 | NTR | Blood | DUS2L | 0.01 | 0.01 | bslmm | 263 | 0.01 | 3.6e-03 | 4.0 | 5.2 | 1.9e-07 | 0.07 | 0.08 | 0.80 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TERF2 | 0.04 | 0.04 | blup | 47 | 0.03 | 2.6e-04 | 4.9 | -5.5 | 2.9e-08 | -0.88 | 0.01 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | 0.04 | 0.04 | blup | 37 | 0.03 | 2.6e-03 | 4.7 | -5.2 | 1.7e-07 | -0.93 | 0.01 | 0.96 | FALSE | |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | 0.05 | 0.04 | blup | 36 | 0.04 | 9.8e-05 | 5.0 | -5.2 | 2.1e-07 | -0.94 | 0.01 | 0.98 | FALSE |