Best TWAS P=3.76e-08 · Best GWAS P=2.74e-08 conditioned to 0.121
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SETD6 | 0.13 | 0.09 | lasso | 3 | 0.09 | 2.3e-07 | -5.5 | -5.4 | 8.4e-08 | 0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Heart Left Ventricle | SETD6 | 0.19 | 0.11 | lasso | 5 | 0.08 | 3.8e-05 | -5.3 | -5.4 | 5.1e-08 | 0.85 | 0.02 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | SETD6 | 0.09 | 0.01 | enet | 7 | 0.03 | 2.6e-03 | -5.5 | -5.5 | 3.8e-08 | 0.87 | 0.01 | 0.93 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SETD6 | 0.27 | 0.00 | blup | 52 | 0.06 | 1.9e-04 | 4.2 | -5.1 | 2.9e-07 | 0.49 | 0.01 | 0.56 | FALSE |