[Hub]/) : Traits : Bipolar Disorder or Schizophrenia :

chr17:18,051,975-20,017,091

Best TWAS P=2.85e-09 · Best GWAS P=2.08e-07 conditioned to 0.224

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-135L13.4 0.38 0.15 enet 32 0.21 1.6e-16 -4.8 -5.3 1.0e-07 0.70 0.04 0.96 FALSE
2 GTEx Breast Mammary Tissue EPN2 0.14 0.08 lasso 7 0.09 3.6e-05 -5.1 -5.5 4.3e-08 0.77 0.01 0.96 FALSE
3 GTEx Breast Mammary Tissue (Male) EPN2 0.06 -0.01 lasso 4 0.03 7.5e-02 -5.1 -5.7 1.3e-08 0.73 0.02 0.23 FALSE
4 GTEx Breast Mammary Tissue (Female) EPN2 0.19 0.00 lasso 5 0.00 3.9e-01 -5.1 -5.5 3.2e-08 0.70 0.02 0.44 FALSE
5 GTEx Testis RNF112 0.13 0.16 lasso 2 0.13 3.4e-06 -5.0 -5.3 1.3e-07 0.75 0.01 0.98 FALSE
6 NTR Blood GRAP 0.05 0.03 blup 177 0.05 1.7e-14 -3.7 5.9 2.8e-09 -0.65 0.10 0.89 TRUE
7 YFS Blood PRPSAP2 0.05 0.04 blup 154 0.05 6.6e-17 3.3 5.8 6.2e-09 -0.49 0.85 0.05 TRUE
8 YFS Blood RNF112 0.05 0.05 lasso 3 0.05 3.5e-16 -5.1 -5.2 2.5e-07 0.71 0.01 0.99 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma RNF112 0.04 0.04 lasso 2 0.03 5.8e-05 -5.1 -5.4 7.7e-08 0.86 0.00 0.98 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma GRAPL 0.04 0.02 enet 2 0.02 1.3e-02 -5.0 5.1 3.1e-07 -1.00 0.00 0.58 FALSE