Best TWAS P=2.62e-09 · Best GWAS P=2.39e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | STK4 | 0.12 | 0.12 | enet | 16 | 0.13 | 2.9e-16 | -5.9 | 6.0 | 2.6e-09 | -0.99 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | STK4 | 0.04 | 0.03 | blup | 88 | 0.03 | 7.1e-05 | 4.3 | 5.2 | 1.7e-07 | -0.78 | 0.27 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | STK4 | 0.05 | 0.02 | blup | 89 | 0.03 | 1.1e-03 | -5.3 | 5.5 | 3.4e-08 | -0.61 | 0.16 | 0.52 | FALSE |