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Bipolar Disorder or Schizophrenia
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chr20:42,924,921-44,408,428
Best TWAS P=2.62e-09 · Best GWAS P=2.39e-09 conditioned to 1
43M
43.2M
43.4M
43.6M
43.8M
44M
44.2M
44.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
STK4
0.12
0.12
enet
16
0.13
2.9e-16
-5.9
6.0
2.6e-09
-0.99
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
STK4
0.05
0.02
blup
89
0.03
1.1e-03
-5.3
5.5
3.4e-08
-0.61
0.16
0.52
FALSE
2
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
STK4
0.04
0.03
blup
88
0.03
7.1e-05
4.3
5.2
1.7e-07
-0.78
0.27
0.67
FALSE