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Bipolar Disorder or Schizophrenia
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chr20:36,681,910-38,094,711
Best TWAS P=2.52e-09 · Best GWAS P=2.62e-10 conditioned to 0.000773
36.6M
36.8M
37M
37.2M
37.4M
37.6M
37.8M
38M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
ACTR5
0.16
0.14
blup
408
0.16
6.8e-50
-4.7
6.0
2.5e-09
-0.62
0.98
0.02
TRUE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
ACTR5
0.04
0.06
lasso
4
0.06
5.4e-07
-5.1
-5.5
3.9e-08
0.72
0.29
0.70
FALSE
2
GTEx
Testis
ACTR5
0.59
0.60
lasso
9
0.63
1.5e-35
-4.9
-5.3
1.3e-07
0.64
0.72
0.28
FALSE
1
GTEx
Skin Not Sun Exposed Suprapubic
ACTR5
0.11
0.06
lasso
6
0.06
3.1e-04
-5.3
5.3
1.4e-07
-0.85
0.27
0.66
FALSE