Best TWAS P=2.52e-09 · Best GWAS P=2.62e-10 conditioned to 0.000773
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | ACTR5 | 0.11 | 0.06 | lasso | 6 | 0.06 | 3.1e-04 | -5.3 | 5.3 | 1.4e-07 | -0.85 | 0.27 | 0.66 | FALSE |
| 2 | GTEx | Testis | ACTR5 | 0.59 | 0.60 | lasso | 9 | 0.63 | 1.5e-35 | -4.9 | -5.3 | 1.3e-07 | 0.64 | 0.72 | 0.28 | FALSE |
| 3 | YFS | Blood | ACTR5 | 0.16 | 0.14 | blup | 408 | 0.16 | 6.8e-50 | -4.7 | 6.0 | 2.5e-09 | -0.62 | 0.98 | 0.02 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACTR5 | 0.04 | 0.06 | lasso | 4 | 0.06 | 5.4e-07 | -5.1 | -5.5 | 3.9e-08 | 0.72 | 0.29 | 0.70 | FALSE |