Best TWAS P=5.81e-21 · Best GWAS P=2.27e-30 conditioned to 3.51e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CDKN2B | 0.08 | 0.05 | lasso | 4 | 0.06 | 2.4e-07 | 9.1 | 9.4 | 5.8e-21 | 0.77 | 0.94 | 0.05 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | CDKN2B-AS1 | 0.11 | 0.02 | blup | 501 | 0.03 | 1.7e-04 | 9.1 | 7.7 | 1.8e-14 | 0.66 | 0.40 | 0.53 | FALSE |
| 3 | NTR | Blood | CDKN2B | 0.02 | 0.00 | enet | 9 | 0.01 | 2.7e-03 | -1.8 | 6.2 | 4.8e-10 | 0.63 | 0.12 | 0.66 | FALSE |