Hub : Traits :

Coronary Artery Disease (CAD)

57 significantly associated models · 23 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	109098737	110517617	3	1	7.0e-10	2.9e-10	1.0e+00	100	PSRC1
2	2	202952678	204788156	7	1	3.9e-11	1.8e-11	1.0e+00	100	ICA1L
3	3	137189600	138819532	2	1	4.1e-08	3.3e-08	2.4e-01	96	MRAS
4	6	12020241	13990267	2	1	2.4e-13	2.5e-11	9.5e-01	100	RP1-257A7.5
5	8	19547307	20071503	1	1	8.4e-08	3.0e-07	9.2e-02	89	LPL
6	9	21303958	22819407	2	1	5.8e-21	2.3e-30	3.5e-11	67	CDKN2B
7	9	135883620	136399075	1	1	8.2e-08	1.2e-07	1.7e-02	80	ABO
8	12	111882485	112443960	1	1	1.4e-07	1.4e-07	1.0e+00	100	ACAD10
9	15	78360691	79802863	2	2	9.6e-11	2.9e-09	4.7e-03	77	ADAMTS7 MORF4L1
10	17	46258510	47685050	1	1	2.9e-07	3.6e-06	2.4e-02	76	RP11-463M16.4
11	19	10793749	12191233	1	1	4.2e-08	9.7e-10	1.0e+00	100	EPOR

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Depressed Affect (Nagel 2018)	1.61	1	0	0.0	0.00	1.0e+00	ICA1L
Alzheimer’s Disease (in father)	1.42	1	0	0.0	0.00	1.0e+00	ICA1L
Alzheimer’s Disease (including proxy)	1.59	1	0	0.0	0.00	1.0e+00	ICA1L
Irritable Bowel Disease (IBD)	0.89	1	0	0.0	0.00	1.0e+00	ACAD10
Reaction Time	2.46	1	1	2.2	0.00	1.0e+00	ACAD10
Breast Cancer	1.37	1	0	0.0	0.00	1.0e+00	CDKN2B
Ovarian Cancer	3.14	1	0	0.0	0.00	1.0e+00	ABO
HDL Cholesterol	24.98	2	2	4.4	0.00	1.0e+00	LPL PSRC1
LDL Cholesterol	54.97	4	3	6.7	0.65	3.5e-01	ABO ACAD10 EPOR PSRC1
Primary Biliary Cirrhosis	2.69	2	0	0.0	0.00	1.0e+00	ACAD10 EPOR
Triglycerides	25.44	1	1	2.2	0.00	1.0e+00	LPL
Type 2 Diabetes (T2D) (2012)	3.84	1	0	0.0	0.00	1.0e+00	CDKN2B
Blood Eosinophil Count	8.49	5	2	4.4	-0.07	9.1e-01	ABO ACAD10 EPOR ICA1L LPL
Blood Platelet Count	1.73	7	3	6.7	0.36	4.3e-01	ACAD10 ADAMTS7 CDKN2B ICA1L LPL MORF4L1 RP11-463M16.4
Blood Red Count	3.22	3	2	4.4	0.00	1.0e+00	ABO ACAD10 RP1-257A7.5
Blood White Count	6.45	5	2	4.4	0.02	9.8e-01	ABO ACAD10 CDKN2B EPOR RP1-257A7.5
Heel T-Score	1.37	2	1	2.2	0.00	1.0e+00	ABO PSRC1
BMI	1.66	5	1	2.2	-0.19	7.6e-01	ICA1L LPL MRAS RP11-463M16.4 RP1-257A7.5
Height	1.43	8	4	8.9	-0.72	4.4e-02	ABO ACAD10 EPOR ICA1L LPL MRAS PSRC1 RP11-463M16.4
Waist Hip Ratio (WHR)	2.13	3	1	2.2	0.00	1.0e+00	ADAMTS7 LPL MRAS
Systolic Blood Pressure	4.78	8	4	8.9	0.48	2.3e-01	ABO ACAD10 EPOR ICA1L MORF4L1 MRAS RP11-463M16.4 RP1-257A7.5
Smoking Status	2.82	2	0	0.0	0.00	1.0e+00	ICA1L RP11-463M16.4
Allergy or Eczema	1.68	2	1	2.2	0.00	1.0e+00	ABO ACAD10
Cardiovascular Disease	8.48	6	6	13.3	0.98	5.8e-04	ACAD10 EPOR LPL MRAS PSRC1 RP11-463M16.4
Hypothyroidism (self reported)	5.95	1	1	2.2	0.00	1.0e+00	ACAD10
Respiratory disease	2.13	1	1	2.2	0.00	1.0e+00	ICA1L
Type 2 Diabetes (T2D) (2018)	3.43	3	0	0.0	0.00	1.0e+00	LPL MRAS RP11-463M16.4
Lung FEV1/FVC ratio	1.58	4	1	2.2	-0.45	5.5e-01	ABO ACAD10 ICA1L PSRC1
Lung FVC	1.08	2	0	0.0	0.00	1.0e+00	ABO ICA1L
Chronotype (morning person)	1.15	1	0	0.0	0.00	1.0e+00	ACAD10
Hair Pigment	0.45	6	1	2.2	-0.23	6.6e-01	ACAD10 ADAMTS7 CDKN2B EPOR MRAS RP11-463M16.4
Tanning	0.31	1	0	0.0	0.00	1.0e+00	EPOR
Hand grip strength (left)	1.53	2	0	0.0	0.00	1.0e+00	ABO RP1-257A7.5
Number of treatments/medications taken	4.29	2	0	0.0	0.00	1.0e+00	LPL PSRC1
Average weekly spirits intake	1.71	1	0	0.0	0.00	1.0e+00	ICA1L
Systolic blood pressure, automated reading	3.30	5	2	4.4	0.43	4.6e-01	ACAD10 EPOR MRAS RP11-463M16.4 RP1-257A7.5
Angina	19.92	7	4	8.9	0.99	3.3e-05	ADAMTS7 CDKN2B LPL MORF4L1 PSRC1 RP11-463M16.4 RP1-257A7.5
Medication for hormone replacement therapy	1.37	1	0	0.0	0.00	1.0e+00	ICA1L
Medication: Metformin	3.64	3	0	0.0	0.00	1.0e+00	ABO CDKN2B LPL
Pack years adult smoking proportion	5.71	2	2	4.4	0.00	1.0e+00	ADAMTS7 MORF4L1
Impedance of leg (right)	1.13	1	1	2.2	0.00	1.0e+00	RP11-463M16.4
Leg fat-free mass (left)	1.31	4	0	0.0	-0.97	2.7e-02	ACAD10 EPOR MRAS PSRC1
Trunk fat percentage	1.89	3	1	2.2	0.00	1.0e+00	ABO MRAS RP1-257A7.5
Hand grip strength (right)	1.80	2	0	0.0	0.00	1.0e+00	ABO RP1-257A7.5
Townsend deprivation index at recruitment	1.77	1	0	0.0	0.00	1.0e+00	ICA1L
Current tobacco smoking	2.75	1	1	2.2	0.00	1.0e+00	ICA1L
Taking other prescription medications	2.57	2	0	0.0	0.00	1.0e+00	ACAD10 MRAS
Heel bone mineral density (BMD) T-score, automated (left)	1.28	1	0	0.0	0.00	1.0e+00	ABO
High blood pressure	5.00	5	4	8.9	0.16	8.0e-01	ABO ACAD10 MRAS RP11-463M16.4 RP1-257A7.5
Hayfever, allergic rhinitis or eczema	1.41	1	0	0.0	0.00	1.0e+00	ABO
Multivitamins +/- minerals	2.19	1	0	0.0	0.00	1.0e+00	MORF4L1
Diverticular disease/diverticulitis (self-reported)	3.12	2	0	0.0	0.00	1.0e+00	ACAD10 ICA1L
Medication: Atenolol	5.47	1	0	0.0	0.00	1.0e+00	ACAD10
Medication: Levothyroxine sodium	4.79	1	1	2.2	0.00	1.0e+00	ACAD10
Sitting height	1.20	3	1	2.2	0.00	1.0e+00	ICA1L MORF4L1 RP11-463M16.4
Chronic bronchitis/emphysema (father)	2.87	1	0	0.0	0.00	1.0e+00	ADAMTS7
High blood pressure (mother)	3.43	3	0	0.0	0.00	1.0e+00	MRAS RP11-463M16.4 RP1-257A7.5
Body mass index (BMI)	1.54	2	0	0.0	0.00	1.0e+00	RP11-463M16.4 RP1-257A7.5
Impedance of leg (left)	1.32	2	1	2.2	0.00	1.0e+00	LPL RP11-463M16.4
Leg predicted mass (left)	1.32	4	0	0.0	-0.98	2.4e-02	ACAD10 EPOR MRAS PSRC1
Trunk fat mass	1.57	4	0	0.0	-0.58	4.2e-01	ABO ACAD10 MRAS RP1-257A7.5
Waist circumference	1.35	3	0	0.0	0.00	1.0e+00	ACAD10 ICA1L RP1-257A7.5
Number of incorrect matches in round	1.15	1	0	0.0	0.00	1.0e+00	MRAS
Past tobacco smoking	2.84	2	0	0.0	0.00	1.0e+00	ACAD10 RP11-463M16.4
Had menopause	2.25	1	0	0.0	0.00	1.0e+00	LPL
Forced vital capacity (FVC)	1.41	3	0	0.0	0.00	1.0e+00	ABO EPOR ICA1L
Heel bone mineral density (BMD) T-score, automated (right)	1.43	1	0	0.0	0.00	1.0e+00	ABO
Heart attack	17.02	6	3	6.7	0.99	5.3e-05	CDKN2B ICA1L LPL MRAS PSRC1 RP1-257A7.5
Allergy	3.31	1	1	2.2	0.00	1.0e+00	ABO
Medication: Ramipril	3.00	1	0	0.0	0.00	1.0e+00	MRAS
Medication: Simvastatin	17.04	6	3	6.7	0.93	7.0e-03	ABO CDKN2B EPOR LPL MRAS PSRC1
Illnesses of siblings	2.76	1	0	0.0	0.00	1.0e+00	RP11-463M16.4
Weight	1.43	4	0	0.0	-0.96	3.6e-02	ACAD10 EPOR MRAS RP1-257A7.5
Impedance of arm (right)	2.66	3	1	2.2	0.00	1.0e+00	ABO CDKN2B RP11-463M16.4
Arm fat percentage (right)	2.54	3	1	2.2	0.00	1.0e+00	ABO ICA1L RP1-257A7.5
Trunk fat-free mass	1.95	4	4	8.9	-0.99	7.8e-03	ABO ACAD10 EPOR PSRC1
Hip circumference	1.65	3	0	0.0	0.00	1.0e+00	ACAD10 ADAMTS7 MRAS
Father's age at death	6.33	4	0	0.0	-0.97	3.1e-02	ABO CDKN2B LPL PSRC1
Frequency of tiredness / lethargy in last 2 weeks	1.59	1	0	0.0	0.00	1.0e+00	ACAD10
Falls in the last year	1.46	1	0	0.0	0.00	1.0e+00	ICA1L
Forced expiratory volume in 1-second (FEV1)	1.67	2	0	0.0	0.00	1.0e+00	ABO EPOR
Asthma	1.52	1	0	0.0	0.00	1.0e+00	ICA1L
Medication: Ibuprofen (e.g. Nurofen)	4.12	1	1	2.2	0.00	1.0e+00	RP1-257A7.5
Medication: Cholesterol lowering	21.71	5	3	6.7	0.92	2.7e-02	ABO CDKN2B EPOR LPL PSRC1
Lung cancer (father)	4.26	2	0	0.0	0.00	1.0e+00	ADAMTS7 MORF4L1
Illnesses of mother	3.12	1	0	0.0	0.00	1.0e+00	CDKN2B
Forced expiratory volume in 1-second (FEV1), Best measure	1.93	2	0	0.0	0.00	1.0e+00	ABO EPOR
Pulse wave Arterial Stiffness index	2.76	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Impedance of arm (left)	2.79	3	1	2.2	0.00	1.0e+00	ABO ACAD10 RP11-463M16.4
Arm fat mass (right)	1.81	4	0	0.0	-0.60	4.0e-01	ABO ACAD10 MRAS RP1-257A7.5
Trunk predicted mass	1.95	4	4	8.9	-0.99	7.9e-03	ABO ACAD10 EPOR PSRC1
Standing height	1.40	5	2	4.4	-0.62	2.7e-01	ACAD10 EPOR ICA1L PSRC1 RP11-463M16.4
Birth weight of first child	2.01	2	0	0.0	0.00	1.0e+00	ACAD10 EPOR
Peak expiratory flow (PEF)	1.81	2	1	2.2	0.00	1.0e+00	ABO EPOR
Pulse wave reflection index	2.50	1	0	0.0	0.00	1.0e+00	ICA1L
Blood clot in the leg (DVT)	20.92	1	1	2.2	0.00	1.0e+00	ABO
Medication: Paracetamol	3.22	2	1	2.2	0.00	1.0e+00	ICA1L RP1-257A7.5
Headache pain in last month	5.09	3	1	2.2	0.00	1.0e+00	ACAD10 ICA1L RP1-257A7.5
Medication for cholesterol, blood pressure or diabetes	7.85	4	2	4.4	-0.94	5.7e-02	EPOR LPL PSRC1 RP11-463M16.4
Glaucoma (self-reported)	4.23	1	1	2.2	0.00	1.0e+00	CDKN2B
Hypothyroidism/myxoedema (self-reported)	4.76	1	1	2.2	0.00	1.0e+00	ACAD10
Birth weight	1.47	1	0	0.0	0.00	1.0e+00	ACAD10
Chronic bronchitis/emphysema (mother)	2.78	1	0	0.0	0.00	1.0e+00	MORF4L1
Forced vital capacity (FVC), Best measure	1.70	2	0	0.0	0.00	1.0e+00	EPOR ICA1L
Body fat percentage	1.83	4	0	0.0	-0.59	4.1e-01	ABO ICA1L MRAS RP1-257A7.5
Leg fat percentage (right)	1.46	2	0	0.0	0.00	1.0e+00	ICA1L RP1-257A7.5
Arm fat-free mass (right)	2.13	4	2	4.4	-0.99	1.0e-02	ABO ACAD10 EPOR PSRC1
Comparative body size at age 10	0.89	1	0	0.0	0.00	1.0e+00	RP11-463M16.4
Wheeze or whistling in the chest in last year	1.91	1	0	0.0	0.00	1.0e+00	ICA1L
Pulse wave peak to peak time	2.73	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Qualifications: College or University degree	1.27	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Medication for pain relief, constipation, heartburn	2.80	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Medication: Blood pressure	3.62	1	1	2.2	0.00	1.0e+00	RP11-463M16.4
Angina (self-reported)	20.41	7	5	11.1	0.99	4.5e-05	ADAMTS7 CDKN2B LPL MORF4L1 PSRC1 RP11-463M16.4 RP1-257A7.5
Migraine (self-reported)	5.31	2	1	2.2	0.00	1.0e+00	ICA1L RP1-257A7.5
Medication: Ibuprofen	3.77	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Mean time to correctly identify matches	2.62	1	1	2.2	0.00	1.0e+00	ACAD10
Heart disease (mother)	10.72	6	1	2.2	0.99	6.1e-05	ABO ACAD10 ADAMTS7 CDKN2B MORF4L1 RP1-257A7.5
Whole body fat mass	1.60	3	0	0.0	0.00	1.0e+00	ACAD10 MRAS RP1-257A7.5
Leg fat mass (right)	1.47	3	0	0.0	0.00	1.0e+00	ACAD10 MRAS RP1-257A7.5
Arm predicted mass (right)	2.10	5	2	4.4	-0.98	3.7e-03	ABO ACAD10 EPOR MRAS PSRC1
Pulse rate, automated reading	1.78	2	0	0.0	0.00	1.0e+00	ABO RP1-257A7.5
Alcohol intake frequency.	1.91	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Comparative height size at age 10	1.20	2	1	2.2	0.00	1.0e+00	ACAD10 PSRC1
Overall health rating	1.81	1	0	0.0	0.00	1.0e+00	RP11-463M16.4
Chest pain or discomfort	2.37	2	0	0.0	0.00	1.0e+00	CDKN2B LPL
Medication: Aspirin	11.23	7	2	4.4	0.99	1.8e-05	ABO CDKN2B EPOR LPL MRAS PSRC1 RP11-463M16.4
Knee pain experienced in last month	2.51	2	0	0.0	0.00	1.0e+00	ICA1L RP1-257A7.5
Hypertension (Self-reported)	4.66	5	3	6.7	0.16	8.0e-01	ABO ACAD10 MRAS RP11-463M16.4 RP1-257A7.5
Illnesses of father: Heart disease	19.55	10	5	11.1	0.99	6.9e-08	ABO ADAMTS7 CDKN2B EPOR ICA1L LPL MORF4L1 MRAS PSRC1 RP1-257A7.5
Smoking status: Previous	2.69	1	1	2.2	0.00	1.0e+00	ACAD10
Forced expiratory volume in 1-second (FEV1), predicted	1.51	1	0	0.0	0.00	1.0e+00	EPOR
Whole body fat-free mass	1.62	4	2	4.4	-0.99	1.3e-02	ABO ACAD10 EPOR PSRC1
Leg fat-free mass (right)	1.19	3	0	0.0	0.00	1.0e+00	ACAD10 EPOR PSRC1
Arm fat percentage (left)	2.45	4	1	2.2	-0.46	5.4e-01	ABO ICA1L MRAS RP1-257A7.5
Long-standing illness, disability or infirmity	2.95	2	0	0.0	0.00	1.0e+00	CDKN2B MRAS
Ever had bowel cancer screening	1.38	1	0	0.0	0.00	1.0e+00	ABO
Diabetes diagnosed by doctor	2.82	1	0	0.0	0.00	1.0e+00	MRAS
Medication for cholesterol	5.40	3	0	0.0	0.00	1.0e+00	ACAD10 MRAS PSRC1
Breast cancer (self-reported)	3.37	1	0	0.0	0.00	1.0e+00	CDKN2B
Asthma (self-reported)	1.40	1	0	0.0	0.00	1.0e+00	ICA1L
Medication: Aspirin	11.32	6	2	4.4	0.99	1.3e-04	CDKN2B EPOR LPL MRAS PSRC1 RP11-463M16.4
Illnesses of father: None of the above (group 1)	5.39	1	1	2.2	0.00	1.0e+00	CDKN2B
Smoking status: Current	2.69	1	0	0.0	0.00	1.0e+00	ICA1L
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.74	3	0	0.0	0.00	1.0e+00	ABO ADAMTS7 MORF4L1
Whole body water mass	1.59	4	1	2.2	-0.98	1.6e-02	ABO ACAD10 EPOR PSRC1
Leg predicted mass (right)	1.19	3	0	0.0	0.00	1.0e+00	ACAD10 EPOR PSRC1
Arm fat mass (left)	1.76	3	0	0.0	0.00	1.0e+00	ABO MRAS RP1-257A7.5
Number of self-reported non-cancer illnesses	3.95	3	0	0.0	0.00	1.0e+00	ACAD10 ICA1L PSRC1
Miserableness	1.34	1	0	0.0	0.00	1.0e+00	ICA1L
Guilty feelings	1.65	1	0	0.0	0.00	1.0e+00	ICA1L
Mother's age at death	2.18	1	0	0.0	0.00	1.0e+00	ABO
Eye problems/disorders: Glaucoma	6.25	1	1	2.2	0.00	1.0e+00	CDKN2B
Medication: Blood pressure	4.06	4	0	0.0	0.40	6.0e-01	ABO ACAD10 ADAMTS7 MRAS
High cholesterol (Self-reported)	28.62	5	4	8.9	0.79	1.1e-01	ABO EPOR ICA1L LPL PSRC1
Medication: Bendroflumethiazide	4.20	2	0	0.0	0.00	1.0e+00	ADAMTS7 RP11-463M16.4
Medication: Paracetamol	2.06	1	0	0.0	0.00	1.0e+00	RP1-257A7.5
Medication: Atorvastatin	16.46	5	3	6.7	0.94	1.6e-02	ABO CDKN2B EPOR LPL PSRC1
Ever smoked	2.45	1	0	0.0	0.00	1.0e+00	ACAD10
Basal metabolic rate	1.53	3	1	2.2	0.00	1.0e+00	ACAD10 EPOR PSRC1
Leg fat percentage (left)	1.38	2	0	0.0	0.00	1.0e+00	ICA1L RP1-257A7.5
Arm fat-free mass (left)	2.06	4	2	4.4	-0.97	2.7e-02	ABO ACAD10 EPOR PSRC1
Number of operations (self-reported)	1.53	1	0	0.0	0.00	1.0e+00	ABO
Diastolic blood pressure, automated reading	6.14	8	3	6.7	-0.15	7.1e-01	ABO ACAD10 ADAMTS7 CDKN2B ICA1L MORF4L1 MRAS RP11-463M16.4
Vascular/heart problems diagnosed by doctor	5.09	4	3	6.7	-0.59	4.1e-01	ABO ACAD10 MRAS RP11-463M16.4
Cholesterol lowering medication	18.67	7	4	8.9	0.84	1.9e-02	ABO CDKN2B EPOR ICA1L LPL MRAS PSRC1
Pain experienced in last month	2.27	2	0	0.0	0.00	1.0e+00	ACAD10 RP1-257A7.5
Basal cell carcinoma (self-reported)	2.49	1	0	0.0	0.00	1.0e+00	CDKN2B
Heart attack/myocardial infarction (self-reported)	17.52	7	3	6.7	0.99	5.1e-05	ACAD10 CDKN2B ICA1L LPL MRAS PSRC1 RP1-257A7.5
Deep venous thrombosis (DVT) (self-reported)	20.81	1	1	2.2	0.00	1.0e+00	ABO
Heart disease (siblings)	6.47	3	0	0.0	0.00	1.0e+00	ADAMTS7 PSRC1 RP1-257A7.5
Pack years of smoking	5.08	2	2	4.4	0.00	1.0e+00	ADAMTS7 MORF4L1
Impedance of whole body	1.60	3	1	2.2	0.00	1.0e+00	ABO PSRC1 RP11-463M16.4
Leg fat mass (left)	1.41	3	0	0.0	0.00	1.0e+00	ACAD10 MRAS RP1-257A7.5
Arm predicted mass (left)	2.16	4	2	4.4	-0.98	2.1e-02	ABO ACAD10 EPOR PSRC1

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	3	0.097	1.4
GTEx	Adipose Visceral Omentum	1	0.055	1.5
GTEx	Adrenal Gland	0	0.000	1.4
GTEx	Artery Aorta	4	0.151	1.5
GTEx	Artery Coronary	3	0.280	1.5
GTEx	Artery Tibial	4	0.119	1.4
GTEx	Brain Caudate basal ganglia	0	0.000	1.4
GTEx	Brain Cerebellar Hemisphere	0	0.000	1.3
GTEx	Brain Cerebellum	0	0.000	1.3
GTEx	Brain Cortex	0	0.000	1.4
GTEx	Brain Frontal Cortex BA9	1	0.120	1.5
GTEx	Brain Hippocampus	0	0.000	1.2
GTEx	Brain Hypothalamus	0	0.000	1.3
GTEx	Brain Nucleus accumbens basal ganglia	0	0.000	1.2
GTEx	Brain Putamen basal ganglia	0	0.000	1.5
GTEx	Breast Mammary Tissue	0	0.000	1.4
GTEx	Breast Mammary Tissue (Male)	0	0.000	1.4
GTEx	Breast Mammary Tissue (Female)	0	0.000	1.4
GTEx	Cells EBV-transformed lymphocytes	1	0.078	1.4
GTEx	Cells Transformed fibroblasts	3	0.079	1.4
GTEx	Colon Sigmoid	0	0.000	1.4
GTEx	Colon Transverse	0	0.000	1.4
GTEx	Esophagus Gastroesophageal Junction	0	0.000	1.4
GTEx	Esophagus Mucosa	1	0.034	1.4
GTEx	Esophagus Muscularis	0	0.000	1.4
GTEx	Heart Atrial Appendage	0	0.000	1.4
GTEx	Heart Left Ventricle	0	0.000	1.3
GTEx	Liver	1	0.153	1.5
GTEx	Lung	0	0.000	1.4
GTEx	Muscle Skeletal	2	0.077	1.4
GTEx	Nerve Tibial	2	0.052	1.4
GTEx	Ovary	0	0.000	1.4
GTEx	Pancreas	0	0.000	1.4
GTEx	Pituitary	0	0.000	1.3
GTEx	Prostate	0	0.000	1.4
GTEx	Skin Not Sun Exposed Suprapubic	2	0.090	1.4
GTEx	Skin Sun Exposed Lower leg	1	0.031	1.4
GTEx	Small Intestine Terminal Ileum	0	0.000	1.3
GTEx	Spleen	0	0.000	1.4
GTEx	Stomach	0	0.000	1.4
GTEx	Testis	1	0.035	1.4
GTEx	Thyroid	1	0.028	1.4
GTEx	Uterus	0	0.000	1.3
GTEx	Vagina	0	0.000	1.3
GTEx	Whole Blood	1	0.057	1.5
METSIM	Adipose	2	0.048	1.3
NTR	Blood	1	0.044	1.3
ROSMAP	Brain Pre-frontal Cortex	2	0.050	1.3
YFS	Blood	0	0.000	1.3
CommonMind	Brain Pre-frontal Cortex	4	0.081	1.3
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	1	0.072	1.3
The Cancer Genome Atlas	Breast Invasive Carcinoma	1	0.027	1.3
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	1	0.105	1.4
The Cancer Genome Atlas	Colon Adenocarcinoma	3	0.173	1.4
The Cancer Genome Atlas	Esophageal Carcinoma	0	0.000	1.3
The Cancer Genome Atlas	Glioblastoma Multiforme	0	0.000	1.4
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	0	0.000	1.3
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	2	0.057	1.3
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	1	0.058	1.3
The Cancer Genome Atlas	Brain Lower Grade Glioma	1	0.027	1.3
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	1	0.104	1.4
The Cancer Genome Atlas	Lung Adenocarcinoma	1	0.040	1.3
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	1	0.047	1.3
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	0	0.000	1.4
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	0	0.000	1.3
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	0	0.000	1.4
The Cancer Genome Atlas	Prostate Adenocarcinoma	0	0.000	1.3
The Cancer Genome Atlas	Rectum Adenocarcinoma	1	0.167	1.4
The Cancer Genome Atlas	Soft Tissue Sarcoma	0	0.000	1.4
The Cancer Genome Atlas	Skin Cutaneous Melanoma	0	0.000	1.3
The Cancer Genome Atlas	Stomach Adenocarcinoma	1	0.069	1.5
The Cancer Genome Atlas	Testicular Germ Cell Tumors	0	0.000	1.2
The Cancer Genome Atlas	Thyroid Carcinoma	1	0.023	1.3
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	0	0.000	1.4