Best TWAS P=2.29e-08 · Best GWAS P=7.45e-08 conditioned to 3.79e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | PARK7 | 0.13 | 0.06 | lasso | 8 | 0.09 | 3.1e-08 | 4.0 | -5.6 | 2.3e-08 | -0.14 | 0.11 | 0.88 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERRFI1 | 0.01 | 0.01 | blup | 27 | 0.00 | 4.3e-02 | -4.7 | 5.2 | 2.3e-07 | 0.19 | 0.01 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PARK7 | 0.04 | 0.03 | blup | 36 | 0.03 | 4.9e-04 | -4.9 | -5.2 | 2.2e-07 | -0.15 | 0.01 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PARK7 | 0.09 | 0.05 | lasso | 4 | 0.07 | 3.4e-08 | 4.0 | -5.2 | 1.7e-07 | -0.16 | 0.05 | 0.93 | FALSE |