[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr1:66,304,567-68,152,438

Best TWAS P=1.56e-69 · Best GWAS P=5.82e-97 conditioned to 9e-25

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IL23R	0.06	0.03	blup	107	0.03	7.0e-03	13.0	17.6	1.6e-69	-0.58	0.06	0.61	TRUE
5	The Cancer Genome Atlas	Rectum Adenocarcinoma	IL23R	0.17	0.03	blup	108	0.15	2.3e-04	-9.3	16.3	1.4e-59	-0.56	0.04	0.52	TRUE
2	NTR	Blood	MIER1	0.03	0.01	bslmm	573	0.01	2.7e-05	-3.4	-8.1	6.6e-16	0.12	0.88	0.00	TRUE
7	The Cancer Genome Atlas	Thyroid Carcinoma	MIER1	0.19	0.05	blup	58	0.06	1.7e-06	1.9	6.1	9.2e-10	-0.19	0.79	0.08	TRUE
6	The Cancer Genome Atlas	Testicular Germ Cell Tumors	IL23R	0.25	0.07	lasso	8	0.05	1.0e-02	6.5	5.6	1.7e-08	-0.15	0.05	0.04	TRUE
4	The Cancer Genome Atlas	Lung Adenocarcinoma	C1orf141	0.12	0.08	enet	37	0.10	1.2e-11	-14.9	8.0	1.6e-15	-0.46	0.01	0.99	FALSE
1	GTEx	Pituitary	SGIP1	0.24	0.15	enet	18	0.19	1.3e-05	1.2	6.4	1.7e-10	-0.29	0.27	0.07	FALSE