[Hub]/) : Traits : Depression (Nagel 2018) : →

chr3:135,273,949-137,261,517

Best TWAS P=3.1e-09 · Best GWAS P=1.05e-08 conditioned to 0.117

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Coronary	RP11-85F14.5	0.15	0.01	lasso	4	0.00	2.3e-01	-5.6	-5.4	6.3e-08	-0.67	0.02	0.85	FALSE
2	GTEx	Esophagus Mucosa	PCCB	0.10	0.12	lasso	3	0.11	4.8e-08	-5.4	-5.6	2.4e-08	-0.88	0.03	0.97	FALSE
3	GTEx	Lung	PCCB	0.07	0.04	lasso	3	0.03	4.2e-03	-5.1	-5.2	1.6e-07	-0.75	0.07	0.82	FALSE
4	YFS	Blood	PCCB	0.13	0.20	lasso	9	0.20	1.3e-64	-5.5	-5.2	1.9e-07	-0.77	0.03	0.97	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	PCCB	0.11	0.03	blup	54	0.04	2.3e-03	-5.1	-5.8	7.6e-09	-0.84	0.01	0.70	FALSE
6	The Cancer Genome Atlas	Esophageal Carcinoma	PCCB	0.15	0.03	blup	54	0.05	9.6e-03	-4.9	-5.6	2.1e-08	-0.82	0.01	0.56	FALSE
7	The Cancer Genome Atlas	Glioblastoma Multiforme	PCCB	0.10	0.03	blup	53	0.02	5.8e-02	-4.9	-5.6	1.8e-08	-0.81	0.01	0.68	FALSE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PCCB	0.12	0.05	enet	7	0.09	9.7e-11	-5.3	-5.9	3.1e-09	-0.81	0.02	0.98	TRUE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STAG1	0.04	0.02	lasso	3	0.02	4.1e-03	5.4	-5.9	3.1e-09	-0.84	0.03	0.91	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	PCCB	0.11	0.10	lasso	3	0.10	1.3e-11	-5.5	-5.3	8.9e-08	-0.80	0.02	0.98	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	STAG1	0.02	0.02	enet	6	0.02	3.5e-03	-5.6	-5.6	2.8e-08	-0.77	0.02	0.91	FALSE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	STAG1	0.05	0.00	blup	151	0.01	2.9e-02	-5.4	-5.5	3.0e-08	-0.81	0.05	0.94	FALSE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PCCB	0.12	0.07	enet	3	0.06	1.0e-04	-5.3	-5.1	2.9e-07	-0.70	0.02	0.94	FALSE
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PCCB	0.12	0.02	lasso	5	0.02	6.7e-02	-5.6	-5.4	7.8e-08	-0.77	0.01	0.78	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	PCCB	0.06	0.02	lasso	2	0.03	2.3e-04	4.3	-5.2	2.1e-07	-0.85	0.03	0.93	FALSE
16	The Cancer Genome Atlas	Soft Tissue Sarcoma	PCCB	0.14	0.10	enet	6	0.10	1.0e-06	-5.1	-5.3	1.1e-07	-0.79	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Soft Tissue Sarcoma	STAG1	0.06	0.06	lasso	1	0.04	2.0e-03	-5.3	-5.3	1.4e-07	-0.78	0.02	0.78	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	PCCB	0.07	0.04	lasso	1	0.02	1.1e-02	-5.4	-5.4	6.6e-08	-0.80	0.01	0.94	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	PCCB	0.06	0.03	enet	8	0.03	2.3e-04	-5.6	-5.2	1.8e-07	-0.70	0.01	0.98	FALSE