[Hub]/) : Traits : Blood Eosinophil Count :

chr5:126,587,995-128,116,643

Best TWAS P=2.05e-10 · Best GWAS P=4.4e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTC-228N24.3 0.24 0.15 enet 16 0.20 3.4e-16 -5.5 6.1 1.1e-09 -0.96 0.01 0.99 FALSE
2 GTEx Adrenal Gland CTC-228N24.3 0.34 0.10 lasso 9 0.09 4.2e-04 -4.6 5.3 1.0e-07 -0.90 0.01 0.99 FALSE
3 GTEx Artery Aorta CTC-228N24.3 0.20 0.04 lasso 8 0.07 7.4e-05 -1.5 5.4 8.5e-08 -0.94 0.04 0.95 FALSE
4 GTEx Artery Coronary CTC-228N24.3 0.31 0.10 lasso 3 0.10 2.9e-04 -6.1 5.3 9.8e-08 -0.90 0.01 0.92 FALSE
5 GTEx Artery Tibial CTC-228N24.3 0.20 0.16 lasso 7 0.14 3.0e-11 -5.5 5.4 5.7e-08 -0.96 0.01 0.99 FALSE
6 GTEx Cells EBV-transformed lymphocytes CTC-228N24.3 0.24 -0.01 enet 26 0.04 2.2e-02 -5.7 5.3 1.0e-07 -0.59 0.03 0.73 FALSE
7 GTEx Colon Sigmoid CTC-228N24.3 0.20 0.22 enet 11 0.23 1.1e-08 -6.1 6.4 2.0e-10 -0.95 0.00 1.00 TRUE
8 GTEx Esophagus Mucosa CTC-228N24.3 0.18 0.14 enet 11 0.14 9.8e-10 -5.5 5.5 4.5e-08 -0.92 0.01 0.99 FALSE
9 GTEx Heart Atrial Appendage CTC-228N24.3 0.22 0.07 lasso 5 0.07 4.1e-04 -6.2 5.4 5.5e-08 -0.90 0.00 0.99 FALSE
10 GTEx Lung CTC-228N24.3 0.18 0.14 enet 16 0.14 3.2e-11 -5.5 6.0 1.5e-09 -0.93 0.01 0.99 FALSE
11 GTEx Nerve Tibial CTC-228N24.3 0.32 0.18 lasso 10 0.16 1.6e-11 -6.1 6.0 2.2e-09 -0.99 0.00 1.00 FALSE
12 GTEx Pancreas CTC-228N24.3 0.14 0.19 lasso 2 0.17 1.1e-07 -5.5 5.5 3.1e-08 -0.96 0.01 0.99 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic CTC-228N24.3 0.29 0.21 lasso 7 0.22 1.7e-12 -5.5 5.8 5.2e-09 -0.96 0.00 1.00 FALSE
14 GTEx Skin Sun Exposed Lower leg CTC-228N24.3 0.29 0.17 enet 12 0.22 4.3e-18 -6.2 5.8 6.2e-09 -0.91 0.00 1.00 FALSE
15 GTEx Stomach CTC-228N24.3 0.17 0.04 lasso 6 0.08 1.5e-04 -5.9 5.3 1.1e-07 -0.83 0.01 0.97 FALSE
16 METSIM Adipose CTC-228N24.3 0.17 0.19 lasso 6 0.18 1.9e-26 -5.5 5.7 1.0e-08 -0.98 0.02 0.98 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma FLJ33630 0.05 0.04 enet 14 0.03 2.1e-07 -5.5 5.4 7.4e-08 -0.84 0.03 0.97 FALSE
18 The Cancer Genome Atlas Glioblastoma Multiforme FLJ33630 0.38 0.20 lasso 5 0.17 6.5e-06 -5.5 5.7 9.2e-09 -0.98 0.00 0.99 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FLJ33630 0.10 0.07 lasso 3 0.08 7.0e-09 -6.1 6.3 3.3e-10 -0.96 0.00 1.00 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ33630 0.19 0.16 enet 4 0.16 1.2e-17 -5.5 5.8 8.9e-09 -0.98 0.01 0.99 FALSE
21 The Cancer Genome Atlas Lung Adenocarcinoma FLJ33630 0.07 0.05 lasso 1 0.04 1.3e-05 -6.1 6.1 8.2e-10 -1.00 0.00 1.00 FALSE
22 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FLJ33630 0.09 0.08 lasso 4 0.09 4.9e-10 -5.5 5.8 8.4e-09 -0.97 0.00 1.00 FALSE
23 The Cancer Genome Atlas Pancreatic Adenocarcinoma FLJ33630 0.08 0.03 lasso 2 0.04 5.7e-03 -6.1 5.7 1.0e-08 -0.93 0.00 0.93 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma FLJ33630 0.08 0.05 blup 70 0.04 4.4e-05 -6.1 6.1 9.4e-10 -0.87 0.00 1.00 FALSE
25 The Cancer Genome Atlas Testicular Germ Cell Tumors FLJ33630 0.26 0.14 lasso 3 0.13 2.2e-05 -5.5 5.7 1.2e-08 -0.95 0.00 0.99 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma FLJ33630 0.10 0.10 lasso 2 0.09 5.3e-09 -5.5 5.5 3.2e-08 -0.96 0.03 0.97 FALSE