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chr5:109,381,583-111,770,880

Best TWAS P=5.62e-74 · Best GWAS P=3.27e-84 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	WDR36	0.05	0.03	enet	13	0.01	1.0e-02	-10.61	-15.1	1.6e-51	-0.41	0.12	0.50	FALSE
2	GTEx	Adipose Subcutaneous	WDR36	0.14	0.06	lasso	6	0.04	2.1e-04	-18.03	-14.6	4.9e-48	-0.10	0.89	0.00	TRUE
3	GTEx	Adipose Visceral Omentum	WDR36	0.11	0.08	lasso	4	0.10	8.7e-06	-12.12	-15.8	5.8e-56	-0.23	0.84	0.01	FALSE
4	GTEx	Artery Tibial	WDR36	0.11	0.05	lasso	5	0.07	3.2e-06	-12.12	-11.4	4.6e-30	-0.04	0.88	0.01	FALSE
5	GTEx	Brain Cerebellar Hemisphere	WDR36	0.32	0.12	lasso	7	0.17	4.8e-05	-1.81	-8.8	2.0e-18	-0.30	0.12	0.11	FALSE
6	GTEx	Brain Cerebellum	WDR36	0.26	0.22	lasso	4	0.27	1.5e-08	-1.81	-5.5	4.1e-08	-0.24	0.43	0.05	FALSE
7	GTEx	Cells Transformed fibroblasts	WDR36	0.28	0.10	enet	16	0.17	6.8e-13	-0.73	-5.2	2.0e-07	0.21	1.00	0.00	TRUE
8	GTEx	Liver	WDR36	0.32	-0.01	enet	19	0.03	5.4e-02	-3.46	-13.6	2.9e-42	-0.31	0.08	0.05	FALSE
9	GTEx	Nerve Tibial	WDR36	0.24	0.04	enet	30	0.07	9.5e-06	-12.12	-7.0	2.6e-12	0.01	0.72	0.01	TRUE
10	GTEx	Skin Not Sun Exposed Suprapubic	WDR36	0.17	0.09	lasso	6	0.08	2.6e-05	-17.79	-17.8	5.4e-71	-0.29	0.85	0.04	FALSE
11	GTEx	Skin Sun Exposed Lower leg	WDR36	0.13	0.03	lasso	9	0.09	8.9e-08	-17.79	-11.6	3.8e-31	-0.13	0.96	0.00	FALSE
12	GTEx	Spleen	SLC25A46	0.25	0.00	enet	6	0.02	1.3e-01	8.32	-8.5	2.5e-17	-0.06	0.07	0.05	FALSE
13	GTEx	Testis	WDR36	0.61	0.37	lasso	10	0.34	5.7e-16	-17.85	-18.2	5.6e-74	-0.40	1.00	0.00	TRUE
14	METSIM	Adipose	CAMK4	0.05	0.01	bslmm	518	0.03	8.3e-05	7.49	8.8	1.3e-18	0.34	0.20	0.39	FALSE
15	METSIM	Adipose	TSLP	0.16	0.18	lasso	7	0.18	8.5e-26	-16.95	16.9	2.5e-64	0.72	1.00	0.00	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	TSLP	0.13	0.08	enet	14	0.09	4.1e-11	-15.70	13.3	2.0e-40	0.56	1.00	0.00	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CAMK4	0.10	0.03	lasso	4	0.04	7.8e-06	7.18	-11.6	7.3e-31	-0.40	0.98	0.00	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	STARD4-AS1	0.07	0.02	enet	19	0.03	5.0e-05	1.60	-8.2	2.4e-16	-0.41	0.05	0.85	FALSE
19	YFS	Blood	SLC25A46	0.03	0.02	enet	12	0.02	9.5e-07	8.32	-13.6	4.9e-42	-0.42	0.91	0.04	TRUE
20	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CAMK4	0.04	0.04	blup	159	0.01	3.6e-02	8.02	-8.5	1.8e-17	-0.18	0.26	0.03	TRUE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	TSLP	0.03	0.03	lasso	2	0.03	5.5e-07	-16.91	15.4	8.1e-54	0.64	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	TSLP	0.08	0.01	blup	39	0.03	5.4e-03	-16.67	9.7	3.2e-22	0.65	0.04	0.12	TRUE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TSLP	0.05	0.02	blup	39	0.02	7.9e-04	-16.67	13.3	4.5e-40	0.80	0.08	0.67	TRUE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	TMEM232	0.09	0.03	blup	160	0.04	3.3e-05	5.20	5.5	2.9e-08	0.00	0.58	0.42	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	TSLP	0.06	0.07	blup	39	0.06	6.4e-07	-16.67	17.9	2.8e-71	0.67	0.99	0.01	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	WDR36	0.04	0.01	blup	73	0.02	4.1e-03	-0.73	-5.2	1.6e-07	0.19	0.03	0.07	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	TSLP	0.02	0.02	blup	39	0.02	1.9e-03	-16.91	16.4	9.4e-61	0.59	0.05	0.07	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TSLP	0.04	0.03	enet	6	0.02	1.6e-03	-16.62	12.8	2.5e-37	0.65	0.06	0.60	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	WDR36	0.04	0.04	lasso	1	0.03	3.7e-03	-17.91	-17.9	9.2e-72	-0.31	0.19	0.03	FALSE
30	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TSLP	0.12	0.11	lasso	3	0.08	6.9e-04	-16.95	17.4	1.2e-67	0.63	0.08	0.36	TRUE
31	The Cancer Genome Atlas	Thyroid Carcinoma	TSLP	0.13	0.14	blup	39	0.15	1.4e-14	-16.67	17.9	1.0e-71	0.65	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	WDR36	0.08	0.02	blup	73	0.05	1.5e-05	-0.90	-11.8	4.3e-32	-0.04	0.41	0.02	FALSE