[Hub]/) : Traits : Blood Eosinophil Count :

chr5:109,381,583-111,770,880

Best TWAS P=5.62e-74 · Best GWAS P=3.27e-84 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WDR36 0.05 0.03 enet 13 0.01 1.0e-02 -10.61 -15.1 1.6e-51 -0.41 0.12 0.50 FALSE
2 GTEx Adipose Subcutaneous WDR36 0.14 0.06 lasso 6 0.04 2.1e-04 -18.03 -14.6 4.9e-48 -0.10 0.89 0.00 TRUE
3 GTEx Adipose Visceral Omentum WDR36 0.11 0.08 lasso 4 0.10 8.7e-06 -12.12 -15.8 5.8e-56 -0.23 0.84 0.01 FALSE
4 GTEx Artery Tibial WDR36 0.11 0.05 lasso 5 0.07 3.2e-06 -12.12 -11.4 4.6e-30 -0.04 0.88 0.01 FALSE
5 GTEx Brain Cerebellar Hemisphere WDR36 0.32 0.12 lasso 7 0.17 4.8e-05 -1.81 -8.8 2.0e-18 -0.30 0.12 0.11 FALSE
6 GTEx Brain Cerebellum WDR36 0.26 0.22 lasso 4 0.27 1.5e-08 -1.81 -5.5 4.1e-08 -0.24 0.43 0.05 FALSE
7 GTEx Cells Transformed fibroblasts WDR36 0.28 0.10 enet 16 0.17 6.8e-13 -0.73 -5.2 2.0e-07 0.21 1.00 0.00 TRUE
8 GTEx Liver WDR36 0.32 -0.01 enet 19 0.03 5.4e-02 -3.46 -13.6 2.9e-42 -0.31 0.08 0.05 FALSE
9 GTEx Nerve Tibial WDR36 0.24 0.04 enet 30 0.07 9.5e-06 -12.12 -7.0 2.6e-12 0.01 0.72 0.01 TRUE
10 GTEx Skin Not Sun Exposed Suprapubic WDR36 0.17 0.09 lasso 6 0.08 2.6e-05 -17.79 -17.8 5.4e-71 -0.29 0.85 0.04 FALSE
11 GTEx Skin Sun Exposed Lower leg WDR36 0.13 0.03 lasso 9 0.09 8.9e-08 -17.79 -11.6 3.8e-31 -0.13 0.96 0.00 FALSE
12 GTEx Spleen SLC25A46 0.25 0.00 enet 6 0.02 1.3e-01 8.32 -8.5 2.5e-17 -0.06 0.07 0.05 FALSE
13 GTEx Testis WDR36 0.61 0.37 lasso 10 0.34 5.7e-16 -17.85 -18.2 5.6e-74 -0.40 1.00 0.00 TRUE
14 METSIM Adipose CAMK4 0.05 0.01 bslmm 518 0.03 8.3e-05 7.49 8.8 1.3e-18 0.34 0.20 0.39 FALSE
15 METSIM Adipose TSLP 0.16 0.18 lasso 7 0.18 8.5e-26 -16.95 16.9 2.5e-64 0.72 1.00 0.00 FALSE
16 ROSMAP Brain Pre-frontal Cortex TSLP 0.13 0.08 enet 14 0.09 4.1e-11 -15.70 13.3 2.0e-40 0.56 1.00 0.00 FALSE
17 ROSMAP Brain Pre-frontal Cortex CAMK4 0.10 0.03 lasso 4 0.04 7.8e-06 7.18 -11.6 7.3e-31 -0.40 0.98 0.00 FALSE
18 ROSMAP Brain Pre-frontal Cortex STARD4-AS1 0.07 0.02 enet 19 0.03 5.0e-05 1.60 -8.2 2.4e-16 -0.41 0.05 0.85 FALSE
19 YFS Blood SLC25A46 0.03 0.02 enet 12 0.02 9.5e-07 8.32 -13.6 4.9e-42 -0.42 0.91 0.04 TRUE
20 The Cancer Genome Atlas Bladder Urothelial Carcinoma CAMK4 0.04 0.04 blup 159 0.01 3.6e-02 8.02 -8.5 1.8e-17 -0.18 0.26 0.03 TRUE
21 The Cancer Genome Atlas Breast Invasive Carcinoma TSLP 0.03 0.03 lasso 2 0.03 5.5e-07 -16.91 15.4 8.1e-54 0.64 1.00 0.00 FALSE
22 The Cancer Genome Atlas Colon Adenocarcinoma TSLP 0.08 0.01 blup 39 0.03 5.4e-03 -16.67 9.7 3.2e-22 0.65 0.04 0.12 TRUE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TSLP 0.05 0.02 blup 39 0.02 7.9e-04 -16.67 13.3 4.5e-40 0.80 0.08 0.67 TRUE
24 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM232 0.09 0.03 blup 160 0.04 3.3e-05 5.20 5.5 2.9e-08 0.00 0.58 0.42 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma TSLP 0.06 0.07 blup 39 0.06 6.4e-07 -16.67 17.9 2.8e-71 0.67 0.99 0.01 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma WDR36 0.04 0.01 blup 73 0.02 4.1e-03 -0.73 -5.2 1.6e-07 0.19 0.03 0.07 FALSE
27 The Cancer Genome Atlas Lung Adenocarcinoma TSLP 0.02 0.02 blup 39 0.02 1.9e-03 -16.91 16.4 9.4e-61 0.59 0.05 0.07 FALSE
28 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TSLP 0.04 0.03 enet 6 0.02 1.6e-03 -16.62 12.8 2.5e-37 0.65 0.06 0.60 FALSE
29 The Cancer Genome Atlas Stomach Adenocarcinoma WDR36 0.04 0.04 lasso 1 0.03 3.7e-03 -17.91 -17.9 9.2e-72 -0.31 0.19 0.03 FALSE
30 The Cancer Genome Atlas Testicular Germ Cell Tumors TSLP 0.12 0.11 lasso 3 0.08 6.9e-04 -16.95 17.4 1.2e-67 0.63 0.08 0.36 TRUE
31 The Cancer Genome Atlas Thyroid Carcinoma TSLP 0.13 0.14 blup 39 0.15 1.4e-14 -16.67 17.9 1.0e-71 0.65 1.00 0.00 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma WDR36 0.08 0.02 blup 73 0.05 1.5e-05 -0.90 -11.8 4.3e-32 -0.04 0.41 0.02 FALSE