Best TWAS P=3.93e-09 · Best GWAS P=3.14e-15 conditioned to 4.53e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | SLU7 | 0.21 | 0.12 | enet | 19 | 0.15 | 8.4e-12 | -6.1 | 5.9 | 3.9e-09 | -0.59 | 0.88 | 0.12 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | SLU7 | 0.22 | 0.12 | lasso | 4 | 0.07 | 1.7e-04 | -6.1 | 5.8 | 8.1e-09 | -0.53 | 0.26 | 0.58 | FALSE |
| 3 | GTEx | Muscle Skeletal | SLU7 | 0.13 | 0.06 | lasso | 3 | 0.08 | 2.9e-08 | -6.1 | 5.6 | 2.7e-08 | -0.50 | 0.97 | 0.02 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | SLU7 | 0.16 | 0.02 | enet | 13 | 0.12 | 6.6e-07 | 1.7 | 5.4 | 8.1e-08 | -0.58 | 0.07 | 0.89 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | SLU7 | 0.13 | 0.08 | enet | 14 | 0.13 | 9.6e-11 | -6.1 | 5.2 | 1.6e-07 | -0.48 | 0.99 | 0.01 | FALSE |
| 6 | YFS | Blood | SLU7 | 0.12 | 0.07 | enet | 16 | 0.09 | 2.6e-27 | 3.9 | -5.7 | 1.6e-08 | 0.27 | 1.00 | 0.00 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SLU7 | 0.07 | 0.04 | enet | 8 | 0.06 | 2.5e-07 | 3.9 | 5.1 | 2.8e-07 | -0.22 | 1.00 | 0.00 | FALSE |