Hub : Genes

SLU7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1670	0.0370	3.3e-08	0.075	0.085	0.138	0.130	0.141	1.7e-09	1.4e-10	1.8e-16	1.5e-15	7.7e-17
2	GTEx	Adipose Subcutaneous	0.2020	0.0620	9.4e-04	0.059	NA	0.099	NA	0.118	1.4e-05	NA	1.7e-08	NA	7.1e-10
3	GTEx	Artery Tibial	0.2088	0.0516	1.4e-05	0.122	NA	0.150	NA	0.133	8.5e-10	NA	8.4e-12	NA	1.4e-10
4	GTEx	Breast Mammary Tissue	0.2160	0.0690	1.2e-03	0.117	NA	0.050	NA	0.071	1.4e-06	NA	1.5e-03	NA	1.7e-04
5	GTEx	Breast Mammary Tissue (Male)	0.4200	0.1451	1.2e-02	-0.013	NA	-0.013	NA	-0.007	8.8e-01	NA	8.9e-01	NA	5.0e-01
6	GTEx	Cells Transformed fibroblasts	0.2040	0.0560	3.6e-04	0.130	NA	0.107	NA	0.109	5.5e-10	NA	2.3e-08	NA	1.7e-08
7	GTEx	Esophagus Muscularis	0.1590	0.0600	5.3e-03	0.185	NA	0.129	NA	0.163	2.2e-11	NA	3.2e-08	NA	4.1e-10
8	GTEx	Muscle Skeletal	0.1253	0.0394	6.2e-04	0.058	NA	0.069	NA	0.080	2.1e-06	NA	2.6e-07	NA	2.9e-08
9	GTEx	Nerve Tibial	0.1857	0.0556	2.8e-04	0.045	NA	0.061	NA	0.048	3.6e-04	NA	3.8e-05	NA	2.5e-04
10	GTEx	Skin Not Sun Exposed Suprapubic	0.1570	0.0550	2.9e-03	0.023	NA	0.116	NA	0.104	1.9e-02	NA	6.6e-07	NA	2.5e-06
11	GTEx	Skin Sun Exposed Lower leg	0.1330	0.0430	9.5e-04	0.082	NA	0.128	NA	0.124	2.7e-07	NA	9.6e-11	NA	1.9e-10
12	GTEx	Thyroid	0.1590	0.0490	4.2e-04	0.002	NA	0.073	NA	0.054	2.1e-01	NA	2.8e-06	NA	5.8e-05
13	YFS	Blood	0.1180	0.0220	0.0e+00	0.069	0.069	0.088	0.082	0.085	1.2e-21	1.3e-21	2.6e-27	2.0e-25	1.9e-26
14	TCGA	Breast Invasive Carcinoma	0.0581	0.0246	1.1e-04	0.002	0.016	0.020	NA	0.010	9.1e-02	2.6e-04	4.8e-05	NA	3.6e-03
15	TCGA	Brain Lower Grade Glioma	0.0685	0.0268	3.2e-06	0.044	0.053	0.059	NA	0.057	9.4e-06	1.1e-06	2.5e-07	NA	4.7e-07
16	TCGA	Lung Squamous Cell Carcinoma	0.0545	0.0208	1.3e-05	0.050	0.041	0.032	NA	0.035	2.2e-06	1.7e-05	1.2e-04	NA	6.9e-05
17	TCGA	Pancreatic Adenocarcinoma	0.1320	0.0620	1.8e-03	0.106	0.079	0.062	NA	0.099	3.3e-05	3.2e-04	1.4e-03	NA	6.1e-05
18	TCGA	Prostate Adenocarcinoma	0.1010	0.0370	5.5e-06	0.042	0.052	0.057	NA	0.055	2.8e-05	3.5e-06	1.4e-06	NA	2.1e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	0.3	0.5	2.2	0.4	-0.2	0.4	0.3	0.8	-0.4	-0.5	0.1	0.3	-0.1	-0.4	1.5	-1.2	-1.5	0.8	-0.1	-0.2	-0.1
Bipolar Disorder or Schizophrenia	0.1	0.2	1.1	-0.2	-0.3	0.5	0.3	0.8	-0.5	-0.5	-0.0	-0.1	-0.2	-0.3	0.5	0.4	-1.0	-0.4	-0.5	-0.7	-0.5
Depressed Affect (Nagel 2018)	0.6	1.3	7.8	-1.1	-0.2	-0.5	-1.0	-1.6	-0.1	0.1	-0.4	-1.3	0.0	0.0	-2.8	2.4	-0.5	-1.4	-0.5	-0.2	-0.7
Depression (Nagel 2018)	1.3	2.0	17.1	-1.0	-0.9	-0.8	-1.5	-2.6	-0.5	-0.4	-1.2	-0.8	-0.2	-0.7	-4.1	1.2	-0.4	-1.0	0.4	-0.7	-1.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	5.5	0.6	0.0	-0.5	0.6	-0.3	-0.1	-0.3	0.3	0.2	0.3	-0.0	2.4	-1.7	0.1	1.0	-0.3	-0.2	0.1
Neuroticism (Nagel 2018)	0.6	1.4	7.3	-0.9	-0.7	-1.5	-1.8	-1.5	0.0	0.3	-1.2	-1.1	-0.7	-0.9	-2.7	1.6	-1.0	-1.0	0.1	0.0	-0.4
Schizophrenia (2018)	0.2	0.3	2.3	-0.6	-0.2	-0.1	0.2	0.3	-0.3	-0.2	-0.1	-0.3	-0.1	0.0	-0.6	1.5	-0.1	-1.1	-0.5	-0.7	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.5	2.5	0.1	0.3	1.0	1.6	-0.1	-0.5	-0.6	0.9	-0.1	0.7	0.7	-1.5	-0.1	0.2	0.1	0.6	-0.5	-0.7
Worry (Nagel 2018)	1.9	4.0	10.3	-2.1	-2.1	-2.8	-3.2	-0.7	-0.8	-0.4	-2.9	-2.1	-2.1	-2.5	-2.6	2.2	-1.6	-2.1	-0.7	-1.0	-1.1
Alzheimer’s Disease (in mother)	0.2	0.3	0.8	-0.1	-0.5	-0.0	0.7	0.8	-0.7	-0.9	-0.3	0.2	-0.6	-0.0	-0.3	-0.7	-0.0	0.8	-0.3	-0.6	0.1
Alzheimer’s Disease (in father)	1.9	2.0	6.6	-1.7	-1.4	-1.1	-0.9	1.1	-1.4	-1.2	-1.3	-0.8	-1.2	-1.4	-2.6	1.2	-0.9	-1.7	-1.5	-2.0	-1.2
Alzheimer’s Disease (including proxy)	1.1	1.7	3.6	-1.4	-1.7	-1.1	-0.6	1.8	-1.6	-1.7	-1.4	-0.3	-1.5	-1.2	-1.9	0.0	-0.7	-0.4	-1.1	-1.7	-0.8
Crohns Disease (2017)	0.3	0.7	2.7	-0.7	-1.0	-0.3	-0.2	0.3	-1.2	-1.3	-0.8	-0.9	-0.7	-0.3	0.4	0.3	-0.9	-0.3	0.1	-1.4	-1.6
Irritable Bowel Disease (IBD)	0.1	0.2	1.3	0.4	0.1	0.2	0.2	0.9	0.1	0.0	0.1	0.2	-0.1	0.6	0.9	-0.3	0.2	-0.2	1.2	-0.5	-0.4
Ulcerative Colitis (UC)	0.5	1.0	2.9	1.3	1.2	1.0	1.0	1.0	1.1	1.0	1.1	1.0	0.6	1.4	1.0	-0.4	0.9	-0.5	1.7	0.3	0.5
Major Depression (MDD)	2.3	2.9	6.6	-1.8	-1.8	-0.2	-0.7	-0.2	-1.9	-1.9	-1.5	-1.1	-0.9	-2.3	-1.9	1.9	-2.6	-1.4	-1.4	-2.1	-2.2
Reaction Time	1.5	2.9	7.0	-2.3	-1.5	-0.6	-1.5	-0.8	-1.4	-1.1	-1.5	-1.2	-1.4	-1.4	-2.1	2.6	-1.1	-2.3	-2.5	-1.8	-1.3
Verbal and Numeric Reasoning (VNR)	0.5	1.3	7.7	1.1	0.7	0.2	1.1	1.1	0.6	0.4	0.8	1.0	0.7	0.3	2.8	-1.9	1.3	1.4	0.4	0.7	0.6
Breast Cancer	0.2	0.4	1.1	-0.4	-0.4	-0.2	0.2	-1.0	-0.9	-1.1	-0.1	-0.2	-0.9	-0.1	-0.1	-0.7	-0.1	0.7	-0.8	-0.4	-0.6
Ovarian Cancer	2.4	3.2	9.8	-1.6	-2.0	-0.3	0.1	-0.8	-2.9	-3.1	-1.0	-1.0	-2.3	-1.6	-1.3	-0.5	-3.0	0.9	-1.2	-1.7	-2.5
Prostate Cancer	0.2	0.2	1.6	-0.4	0.3	0.5	0.0	0.1	0.1	0.2	0.3	-0.2	0.6	0.2	-0.5	1.3	0.7	-0.5	-0.0	0.2	0.2
Age at First Birth	1.7	2.4	7.0	-1.4	-1.9	-2.4	-0.8	0.3	-2.0	-2.1	-1.7	-0.2	-2.1	-1.8	0.3	-0.4	-2.7	0.7	-1.2	-1.2	-1.7
Bipolar Disorder (2011)	1.6	1.5	3.6	-1.3	-1.4	-0.3	-0.9	-0.4	-1.3	-1.2	-1.2	-1.1	-1.3	-1.5	1.9	0.9	-1.3	-1.1	-0.7	-1.5	-1.6
Body Mass Index (BMI) (2010)	0.4	0.6	2.0	0.8	0.5	-0.3	-0.4	0.7	0.9	0.8	0.2	0.7	0.2	0.5	-0.3	-1.4	1.0	1.0	1.1	1.1	0.8
Coronary Artery Disease (CAD)	0.5	0.6	1.5	-0.7	-0.5	0.1	-0.3	-0.0	-0.6	-0.6	-0.4	-0.9	-0.9	-0.4	0.9	1.1	-1.1	-1.2	-0.9	-1.2	-0.5
Crohns Disease (2012)	0.2	0.4	1.5	0.4	-0.1	-0.0	0.4	0.9	-0.3	-0.5	0.1	0.9	0.4	0.1	0.5	-1.0	-1.2	0.9	1.0	-0.0	-0.3
Mean Putamen Volume	0.9	1.0	3.7	-0.9	-0.8	-1.7	-1.9	0.3	0.1	0.4	-1.4	-0.6	-1.1	-1.1	0.8	1.1	-0.5	-1.5	-0.2	-0.5	-0.4
Fasting Glucose	1.3	1.6	7.5	1.3	1.0	0.4	0.4	1.5	0.9	0.9	0.9	1.1	0.4	0.5	1.0	-2.7	0.8	2.1	0.8	1.4	1.7
HbA1C	2.2	2.4	3.9	-1.7	-1.9	-1.8	-1.8	1.6	-1.5	-1.3	-1.9	-1.2	-1.9	-1.9	-2.0	0.7	-1.2	-0.5	-1.5	-1.2	-1.2
HDL Cholesterol	0.8	1.3	2.8	-0.8	-1.3	-1.6	-1.0	-1.4	-1.2	-1.2	-1.3	-0.9	-1.7	-1.2	0.2	0.3	-1.5	-0.1	-1.2	-1.3	-1.0
LDL Cholesterol	1.3	2.1	4.6	1.6	1.7	0.7	1.1	1.1	1.6	1.4	1.7	1.1	1.2	1.4	0.5	-1.9	2.1	1.3	1.3	1.9	1.5
Lupus	2.3	3.5	12.6	-0.7	-0.9	1.2	1.7	-3.6	-2.7	-3.1	0.7	1.0	0.5	-0.4	1.4	-1.2	-3.3	1.5	-0.9	-2.0	-2.1
Neuroticism (2016)	1.3	1.9	6.8	-1.3	-1.5	-0.9	-1.3	-1.2	-1.3	-1.2	-1.5	-2.6	-2.0	-1.7	-1.5	0.5	-0.4	-0.4	-1.1	-1.3	-1.4
Primary Biliary Cirrhosis	0.5	0.7	3.2	-0.6	-0.8	-1.2	-1.0	-0.2	-0.3	-0.2	-1.0	1.0	-1.0	-0.7	0.4	0.4	-1.8	-0.4	-0.9	-0.2	-0.2
Rheumatoid Arthritis	3.6	4.9	12.3	-2.1	-2.3	-0.8	0.4	-2.5	-3.3	-3.5	-1.2	-3.0	-1.8	-1.4	-2.4	0.6	-1.9	-0.5	-1.6	-3.3	-2.9
Schizophrenia (2014)	0.2	0.4	1.3	-0.1	0.1	1.1	1.1	0.6	-0.6	-0.7	0.6	0.4	0.3	0.3	0.3	0.8	-1.1	-0.4	-0.1	-1.0	-0.8
Triglycerides	2.3	3.7	7.0	2.1	2.4	2.1	1.8	-0.1	2.0	1.9	2.5	1.5	2.0	2.6	1.9	-1.3	2.0	1.3	1.6	2.2	1.8
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.6	-0.3	-0.8	-0.8	-0.7	0.2	-0.8	-0.9	-0.5	-0.2	-1.3	-0.3	-0.8	-0.4	-0.8	1.1	-1.1	-0.1	-0.6
Ulcerative Colitis	0.7	1.0	2.4	1.2	0.9	0.8	1.0	1.0	0.8	0.6	0.9	1.5	1.0	0.8	0.6	-1.5	0.2	0.9	1.6	0.7	1.0
Blood Eosinophil Count	2.8	21.3	34.7	4.8	4.5	5.9	5.8	4.2	2.5	1.7	5.6	5.0	5.4	5.2	4.4	-5.7	3.8	5.1	3.9	3.2	4.0
Blood Platelet Count	0.1	0.6	3.1	-0.9	-0.3	0.2	-1.1	-0.7	0.2	0.4	-0.9	1.8	1.1	-0.8	-0.6	-1.3	0.4	-0.5	0.7	0.0	0.3
Blood Red Count	0.1	1.4	5.6	1.2	0.8	1.4	1.0	1.6	0.3	0.0	1.1	2.1	0.5	0.8	0.8	-1.8	-0.3	2.4	0.7	0.8	0.8
Blood White Count	0.1	0.5	2.4	0.4	0.1	0.8	-0.4	-0.2	0.0	-0.1	0.0	1.0	0.1	0.1	-1.0	-1.6	-0.6	1.3	0.8	-0.0	0.9
Heel T-Score	0.1	1.0	8.5	0.7	0.8	1.1	-0.2	0.0	1.1	1.1	0.4	1.1	0.7	0.4	2.9	-0.7	0.5	0.3	0.3	1.0	1.1
BMI	0.4	2.3	7.0	1.0	1.4	2.2	1.1	-1.2	0.9	0.8	1.6	1.6	2.6	2.5	1.5	-1.1	1.4	0.9	1.4	0.8	1.6
Height	0.0	0.9	4.3	-0.1	-0.1	-0.1	1.4	1.5	-1.0	-1.2	0.6	-0.3	0.5	0.1	1.1	-2.1	-0.6	0.7	0.5	-0.8	-1.1
Waist Hip Ratio (WHR)	0.5	2.2	4.6	-1.7	-1.9	-0.8	-1.1	0.1	-1.7	-1.6	-1.7	-1.9	-1.5	-1.6	-1.8	0.1	-2.1	-0.5	-1.8	-1.4	-1.4
Systolic Blood Pressure	0.2	0.8	2.8	-0.2	-1.0	-1.5	-0.7	-0.6	-0.7	-0.8	-1.0	0.1	-0.6	-0.5	0.7	-1.5	-1.7	1.4	0.0	-0.1	-0.6
Smoking Status	0.4	0.9	6.4	1.0	0.0	0.9	1.0	-0.8	-0.6	-1.0	0.7	1.0	0.5	0.5	0.2	-1.4	-0.9	2.5	0.8	0.3	0.2
Allergy or Eczema	1.1	2.9	20.8	-1.7	-1.4	-1.7	-1.3	4.6	-1.3	-1.1	-1.4	-0.7	-1.9	-1.9	0.1	1.1	-1.2	-1.2	-2.0	-1.1	-0.7
Cardiovascular Disease	0.1	0.4	1.1	-0.6	-0.5	-0.7	-0.0	-0.5	-0.8	-0.8	-0.3	-1.1	-0.3	0.3	-0.8	-0.5	-0.6	0.4	-0.9	-0.4	-0.9
Hypothyroidism (self reported)	0.4	0.9	7.9	-0.2	-0.3	0.2	0.9	2.8	-1.0	-1.1	0.4	-1.2	-0.8	-0.1	-0.2	-1.1	0.2	0.5	-1.0	-0.7	-0.7
Respiratory disease	2.7	6.0	12.6	2.6	2.8	3.1	1.8	2.5	2.6	2.5	2.6	3.0	2.8	2.7	1.5	-1.2	1.8	1.3	1.7	2.3	3.5
Type 2 Diabetes (T2D) (2018)	1.2	2.3	4.2	-2.0	-1.7	-2.0	-0.6	-0.2	-2.0	-1.9	-1.4	-1.9	-1.2	-1.5	-0.4	1.5	-1.1	-0.7	-2.0	-1.6	-1.6
Lung FEV1/FVC ratio	0.8	4.0	15.5	-2.2	-1.4	-0.2	-1.3	-2.7	-1.4	-1.1	-1.3	-2.4	-0.5	-1.0	-1.9	3.9	-0.7	-3.4	-1.3	-2.6	-2.4
Lung FVC	0.1	0.3	0.9	-0.2	0.1	0.9	0.9	0.9	-0.3	-0.3	0.3	-0.5	-0.2	-0.1	0.4	0.4	0.5	-0.8	0.4	-0.6	-0.2
Neuroticism	1.1	2.8	6.4	-1.6	-1.5	-1.8	-2.3	-1.2	-0.8	-0.5	-2.0	-2.2	-2.0	-1.7	-2.5	2.1	-1.5	-1.4	-1.1	-0.9	-1.3
Chronotype (morning person)	1.1	2.5	8.2	2.0	1.7	1.3	-0.1	1.6	2.5	2.6	0.9	1.2	1.0	1.0	-0.1	-0.8	0.5	0.6	1.9	2.0	2.9
Hair Pigment	0.1	1.6	6.1	1.1	1.7	2.5	1.7	1.1	1.1	1.0	1.8	-0.8	0.8	1.7	1.3	-0.6	0.5	-0.4	0.9	0.2	0.8
Tanning	0.5	6.2	10.8	3.0	2.5	2.8	1.1	0.8	2.8	2.7	2.1	3.0	2.0	2.2	1.6	-2.7	1.5	3.0	2.7	3.3	3.0
Hand grip strength (left)	0.1	0.3	2.5	-0.0	-0.1	-0.6	0.5	0.6	-0.4	-0.5	0.1	-0.8	-0.0	0.2	1.6	-0.3	-0.4	-0.2	0.4	-0.7	-0.7
Number of treatments/medications taken	0.2	0.3	2.1	-0.4	-0.5	-0.3	-1.0	1.5	-0.2	-0.1	-0.7	0.4	-0.3	-0.4	-0.8	0.2	0.3	-0.1	-0.9	0.0	0.1
Average weekly spirits intake	0.6	0.8	9.3	0.1	-0.1	-0.1	0.7	3.1	-0.5	-0.6	0.3	-0.0	0.2	-0.1	-0.2	-0.8	1.3	0.4	0.5	-0.5	0.0
Sensitivity / hurt feelings	1.2	2.0	9.7	-0.8	-1.6	-1.4	-1.3	-0.6	-1.4	-1.4	-1.5	-1.2	-1.9	-1.9	-3.1	-0.4	-1.1	1.0	-0.2	-0.8	-0.9
Frequency of depressed mood in last 2 weeks	0.9	1.3	10.6	-0.8	-0.6	-0.1	-0.6	-1.6	-0.6	-0.5	-0.6	-1.8	-0.6	-0.0	-3.3	1.0	-0.6	-0.9	-0.0	-0.9	-1.0
Hearing difficulty/problems: Yes	0.4	0.6	2.7	0.3	0.2	-1.0	-0.4	-1.2	0.4	0.4	0.1	-1.6	-0.3	-0.1	-1.2	1.0	-0.7	-1.1	-0.5	-0.5	0.4
Relative age of first facial hair	0.5	0.9	2.1	-0.9	-0.9	-0.9	-1.0	-0.1	-1.1	-1.1	-0.7	-1.1	-1.2	-1.1	1.5	0.3	-0.3	-0.8	-0.6	-1.2	-1.4
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	9.2	0.4	0.9	1.0	0.0	-3.0	1.1	1.1	0.5	-0.6	0.9	0.8	0.5	1.2	-0.1	-1.7	-0.1	0.1	0.6
Ever used hormone-replacement therapy (HRT)	0.4	0.5	4.7	0.2	0.2	-0.3	-0.6	1.0	0.6	0.7	-0.2	-0.0	1.0	0.2	-2.2	0.8	0.2	-0.6	0.4	-0.1	0.5
Ever had hysterectomy (womb removed)	1.0	1.2	4.2	0.8	1.1	1.3	1.4	-0.3	0.8	0.7	1.2	1.5	1.8	2.0	-0.5	-0.1	-0.0	-0.1	1.4	-0.1	0.9
Systolic blood pressure, automated reading	0.2	0.6	3.3	0.2	-0.4	-0.4	-0.7	-1.3	-0.0	-0.1	-0.5	0.7	-0.1	-0.6	1.1	-1.8	-0.6	1.3	0.6	0.5	0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.6	-0.1	0.1	-0.8	-1.0	-1.0	0.7	0.9	-0.5	0.3	0.4	-0.2	-1.3	0.8	0.5	0.0	-0.2	0.9	0.8
Angina	1.6	2.1	4.8	1.8	1.5	0.9	1.9	-0.3	0.9	0.6	1.8	1.7	1.2	1.8	0.9	-1.5	1.1	2.2	2.1	1.3	1.1
Medication for hormone replacement therapy	0.8	0.9	3.9	0.3	0.8	-0.4	-1.1	-0.0	1.7	2.0	-0.0	0.9	0.7	0.5	0.5	0.7	0.5	-0.6	0.4	1.4	1.7
Vitamin and mineral supplements	0.7	1.0	4.0	0.9	0.7	1.1	1.2	-1.3	0.2	-0.1	1.1	0.8	0.9	0.8	2.0	-1.2	-0.5	1.2	1.4	0.4	0.2
Supplements: Zinc	0.4	0.4	2.5	-0.5	-0.2	-0.5	-0.0	-0.3	-0.2	-0.1	-0.2	-1.6	-0.7	-0.3	-1.4	0.8	-0.3	-0.6	-0.5	-0.5	-0.5
Medication: Co-codamol	0.4	0.4	2.5	-0.7	-0.3	-0.1	-0.5	0.7	-0.0	0.1	-0.4	0.3	0.0	-0.1	-1.6	1.3	0.1	-1.4	-0.4	-0.1	-0.2
Medication: Metformin	2.0	2.8	6.9	-2.0	-1.5	-2.6	-1.8	-0.9	-1.0	-0.7	-1.7	-2.1	-1.1	-1.8	-2.1	2.4	-0.4	-1.8	-2.1	-1.0	-1.2
Diabetes (father)	1.3	1.6	5.5	-1.4	-0.9	-1.0	-0.8	-0.3	-0.8	-0.6	-0.9	-2.3	-0.8	-0.9	-0.8	2.2	-1.2	-2.1	-1.5	-1.3	-0.8
Diabetes (mother)	1.2	1.5	3.8	-1.4	-1.1	-0.8	-0.8	-1.0	-1.2	-1.1	-0.9	-1.2	-1.3	-1.1	-2.0	1.3	-0.8	-1.0	-1.0	-1.2	-1.8
Severe depression (siblings)	0.3	0.3	3.5	0.4	0.5	-0.2	0.5	0.4	0.4	0.3	0.5	-0.6	0.5	0.2	-1.9	0.2	0.1	-0.2	-0.3	-0.1	0.2
Pack years adult smoking proportion	0.2	0.3	2.4	0.4	-0.2	0.3	0.7	-0.4	-0.7	-1.0	0.3	0.1	0.3	0.1	-0.0	-0.9	0.2	1.5	0.4	-0.4	-0.1
Impedance of leg (right)	0.1	0.4	2.0	0.0	0.3	-0.1	-0.3	1.4	0.6	0.8	-0.1	0.3	-0.5	-0.3	-0.4	1.1	0.8	-0.9	-0.6	0.4	0.6
Leg fat-free mass (left)	0.2	1.1	4.3	0.8	1.1	0.8	1.0	-0.7	0.7	0.5	1.3	0.4	2.1	1.7	1.6	-1.2	0.6	0.5	1.2	0.5	0.5
Trunk fat percentage	1.6	6.5	12.4	2.5	2.5	2.5	2.0	0.3	2.0	1.7	2.7	3.3	3.5	3.2	2.3	-3.1	2.4	2.6	2.4	2.4	2.6
Hand grip strength (right)	0.1	0.3	2.7	0.4	0.3	-0.3	0.4	0.3	0.2	0.1	0.4	-0.5	0.1	0.6	1.6	-0.8	-0.9	0.0	0.7	-0.2	-0.1
Townsend deprivation index at recruitment	0.4	0.6	2.3	-0.6	-0.7	-1.0	-1.1	1.4	-0.2	-0.1	-0.9	0.2	-1.5	-0.5	-0.5	0.9	0.6	-0.2	-0.9	0.3	0.4
Current tobacco smoking	0.3	0.4	1.7	0.3	0.2	1.3	0.9	-1.0	-0.5	-0.8	0.7	1.1	0.6	0.5	-0.3	0.5	-0.2	0.3	0.4	-0.6	-0.2
Average weekly fortified wine intake	0.9	1.1	2.7	0.5	0.1	-0.5	-1.5	1.0	1.1	1.3	-0.7	1.7	-0.2	-0.2	0.8	-1.0	1.3	0.9	-0.0	1.6	1.6
Maternal smoking around birth	0.8	1.2	4.1	0.7	1.0	0.7	0.7	1.1	0.9	0.9	0.9	0.4	1.5	1.4	-0.6	-0.9	1.9	0.6	2.0	0.9	1.1
Fed-up feelings	1.1	1.9	11.6	-1.1	-0.4	-0.1	-0.3	-1.5	-0.8	-0.6	-0.1	-1.9	-0.3	0.1	-3.4	2.5	-1.1	-1.5	-1.4	-1.1	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	7.3	-0.8	-0.5	-0.7	-1.8	-2.1	0.0	0.3	-1.1	-0.7	-0.2	-0.1	-2.7	1.1	0.1	-1.2	0.1	-0.2	-0.2
Relative age voice broke	1.5	2.3	4.4	-1.7	-1.6	-1.0	-0.9	-0.8	-1.7	-1.7	-1.4	-1.8	-1.8	-1.8	-1.1	0.8	-1.2	-1.4	-1.7	-2.1	-2.0
Taking other prescription medications	0.4	0.6	1.5	0.1	0.8	1.0	0.3	1.2	0.6	0.6	0.8	0.8	0.9	0.8	-0.7	0.9	1.2	-1.0	-0.3	-0.1	0.9
Age when periods started (menarche)	0.1	0.2	0.9	-0.3	-0.3	0.9	-0.1	-0.3	-0.5	-0.6	-0.1	0.6	-0.0	-0.1	0.1	0.2	-1.0	-0.3	-0.2	-0.4	-0.1
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.9	1.1	1.2	1.4	1.3	-0.5	0.7	0.6	1.4	0.9	1.7	1.4	-1.4	-1.1	-0.4	0.8	1.1	0.6	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	7.1	1.3	1.4	0.2	-0.1	-0.6	2.2	2.3	0.7	1.2	1.3	1.0	2.7	0.1	1.5	0.2	0.9	2.0	1.9
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.8	-1.0	-0.5	-1.1	-1.0	-0.6	-0.2	0.1	-0.9	0.2	-0.5	-0.6	-0.6	1.3	-1.1	-1.4	-0.9	-0.1	-0.5
Qualifications: CSEs or equivalent	0.7	0.9	2.2	-1.3	-1.1	-1.4	-1.0	0.5	-0.9	-0.7	-1.2	-0.5	-1.0	-0.9	-0.3	1.3	-0.0	-0.9	-1.5	-0.5	-0.9
Serious illness, injury or assault to yourself	0.9	1.1	2.4	1.6	1.3	1.5	1.5	-0.4	1.1	0.9	1.4	0.1	1.3	1.4	-1.2	-0.7	0.2	0.4	1.1	0.2	0.8
High blood pressure	0.2	0.6	1.9	0.2	0.2	0.7	0.9	-1.0	-0.2	-0.3	0.6	0.6	0.7	1.3	-0.7	-1.4	0.8	0.9	0.7	0.1	-0.4
Hayfever, allergic rhinitis or eczema	1.3	2.9	12.8	-1.9	-1.7	-1.7	-1.8	3.6	-1.4	-1.2	-1.8	-0.9	-2.0	-2.2	-0.3	1.3	-1.5	-1.1	-1.7	-1.0	-1.0
Multivitamins +/- minerals	0.7	0.9	3.2	-0.5	-0.5	-1.3	-1.8	1.4	0.4	0.7	-1.2	-0.0	-0.8	-0.9	-1.3	0.6	1.3	-0.5	-0.9	0.4	0.6
Stomach or abdominal pain in last month	0.4	0.4	1.7	-0.5	-0.3	-0.2	-1.1	-1.0	0.2	0.4	-0.6	0.6	-0.3	-0.0	0.6	1.1	0.7	-0.4	-1.3	0.3	0.4
Supplements: Glucosamine	0.4	0.5	4.3	-0.1	-0.5	0.6	-0.3	0.6	-0.5	-0.5	-0.3	0.8	0.6	-0.5	-2.1	-0.6	-0.2	1.0	0.2	0.2	-0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.8	0.0	-0.5	0.1	0.2	-0.5	-0.6	-0.7	-0.3	-0.2	-0.1	-0.3	0.4	-1.4	-0.8	1.3	-0.1	-0.5	0.3
Medication: Atenolol	0.3	0.4	2.1	-0.1	-0.5	-0.8	-0.6	-0.8	-0.1	-0.1	-0.7	-0.5	-0.7	-0.5	0.2	-1.2	0.3	1.5	0.2	0.2	0.2
Medication: Levothyroxine sodium	0.6	1.0	6.6	0.5	0.2	0.7	1.5	2.6	-0.7	-1.0	0.9	-0.6	-0.3	0.6	-0.0	-1.8	-0.0	1.1	0.0	-0.6	-0.7
Sitting height	0.1	0.5	2.2	0.3	0.8	0.4	0.9	1.5	0.4	0.3	1.0	0.3	1.3	1.0	0.8	-0.6	0.2	-0.3	0.5	0.2	0.2
Chronic bronchitis/emphysema (father)	1.3	1.5	2.8	1.4	1.4	0.6	0.4	0.1	1.4	1.4	1.3	0.0	1.0	1.4	1.5	-1.7	1.5	1.1	1.0	1.5	1.5
High blood pressure (mother)	1.2	1.7	3.1	-1.5	-1.1	-0.7	-0.2	-1.7	-1.4	-1.3	-0.8	-1.2	-0.4	-0.7	-1.1	1.6	-1.6	-1.5	-1.3	-1.7	-1.8
Body mass index (BMI)	0.6	2.4	6.7	1.2	1.4	1.9	1.4	-1.1	0.7	0.5	1.7	1.8	2.6	2.3	1.3	-1.9	1.4	1.5	1.4	0.9	1.0
Impedance of leg (left)	0.1	0.4	3.0	-0.0	0.1	-0.4	-0.4	1.7	0.4	0.6	-0.2	0.6	-0.7	-0.5	-0.7	0.5	0.7	-0.3	-0.5	0.6	0.6
Leg predicted mass (left)	0.2	1.0	3.9	0.7	1.0	0.7	0.9	-0.7	0.6	0.4	1.2	0.3	2.0	1.7	1.5	-1.2	0.6	0.4	1.1	0.4	0.4
Trunk fat mass	1.4	6.2	13.8	2.5	2.5	2.5	2.2	0.1	1.8	1.5	2.8	2.9	3.7	3.3	2.4	-3.1	2.1	2.3	2.5	2.0	2.3
Waist circumference	0.3	1.2	4.2	0.7	0.9	1.8	0.8	-1.5	0.5	0.3	1.1	1.0	2.1	1.5	0.7	-1.5	0.6	0.7	0.6	0.4	0.7
Number of incorrect matches in round	0.2	0.3	2.0	0.6	-0.0	0.3	0.1	0.3	-0.0	-0.2	0.1	0.7	-0.4	0.1	-1.4	-0.9	0.4	0.9	1.0	0.2	0.0
Past tobacco smoking	0.3	0.6	3.4	-0.6	0.2	-0.1	-0.5	-0.4	0.5	0.8	-0.2	0.3	0.1	-0.1	-0.7	1.7	0.9	-1.8	-0.4	-0.1	0.2
Alcohol usually taken with meals	0.3	0.4	1.9	-0.2	-0.3	-0.9	-1.2	-0.1	0.2	0.3	-0.7	-0.4	-0.4	-1.1	0.5	-0.6	-1.4	-0.7	-0.1	0.0	0.2
Nervous feelings	0.8	1.4	7.8	-0.6	-0.9	-1.1	-1.9	-1.1	-0.1	0.2	-1.5	-1.1	-1.8	-0.8	-2.8	0.9	-0.9	-0.8	0.4	-0.2	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.2	-0.4	-0.3	-0.4	-1.3	-1.3	0.2	0.4	-0.8	-1.8	-0.9	-0.3	-1.8	1.3	-0.3	-0.9	-0.0	-0.2	0.0
Hearing difficulty/problems with background noise	0.7	1.1	4.6	-0.9	-0.5	-1.5	-1.1	-0.4	-0.1	0.1	-0.8	-1.2	-0.9	-0.9	-1.3	1.8	-1.2	-2.1	-0.6	-0.9	-0.6
Hair/balding pattern: Pattern 2	1.3	1.6	5.1	-1.3	-1.1	-0.4	0.0	2.3	-1.4	-1.3	-0.8	-0.9	-1.6	-1.2	-2.1	1.1	1.1	-0.9	-1.5	-1.1	-1.1
Had menopause	0.2	0.2	1.9	-0.1	-0.1	-0.1	-0.4	0.3	0.2	0.3	-0.4	-0.5	0.3	-0.2	-1.4	0.4	-0.5	-0.8	0.4	-0.3	-0.1
Had other major operations	1.1	1.3	2.8	-1.4	-1.3	-1.1	-1.2	-1.3	-1.3	-1.2	-1.1	-0.8	-1.0	-1.2	-0.9	0.9	-0.9	-0.5	-1.7	-1.3	-1.0
Forced vital capacity (FVC)	0.3	1.1	4.4	-1.1	-0.8	0.2	0.2	-0.3	-1.4	-1.4	-0.4	-2.1	-1.0	-0.6	-0.2	0.5	-0.8	-1.1	-0.6	-1.9	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	4.3	0.5	0.9	0.3	-0.0	-0.5	1.4	1.6	0.4	0.9	0.8	0.5	2.1	1.0	1.3	-0.3	-0.1	1.4	1.4
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	4.7	-0.6	-0.6	-0.6	-1.1	-1.0	-0.5	-0.4	-0.7	-0.7	-0.7	-0.7	-2.2	1.0	-0.9	-0.2	-0.4	-0.5	-0.8
Qualifications: None of the above	0.8	1.6	7.4	-1.3	-1.4	-1.2	-1.6	2.0	-0.9	-0.7	-1.6	-0.7	-1.8	-1.4	-2.7	0.5	0.4	-0.3	-0.6	-0.1	0.1
Financial difficulties in last 2 years	0.2	0.2	1.7	-0.2	-0.1	0.3	-0.4	0.5	-0.0	0.0	-0.2	0.4	-0.3	-0.2	-0.2	1.0	1.3	-0.4	-0.6	-0.1	0.4
Mouth/teeth dental problems	0.5	0.7	2.1	-0.8	-1.1	-1.2	-0.6	0.6	-0.9	-0.8	-1.1	-0.8	-1.5	-0.8	-0.9	-0.1	-0.2	0.0	-0.6	-0.7	-0.8
Heart attack	1.5	1.9	3.6	1.4	1.7	0.9	0.7	0.4	1.8	1.8	1.3	0.7	1.4	1.6	1.7	-0.4	1.9	0.7	1.4	1.6	1.8
Allergy	0.4	0.9	10.0	0.3	0.3	0.1	1.5	-3.2	-0.2	-0.4	0.7	-0.7	0.6	0.9	-0.2	-0.2	0.8	0.1	0.4	-0.6	-0.9
Pain all over the body in last month	0.3	0.4	2.6	0.2	0.2	0.9	0.1	-0.7	0.1	0.1	0.3	0.8	-0.1	0.7	-1.6	-0.1	1.2	0.0	-0.2	0.1	0.2
Diabetes (self-reported)	0.6	0.9	3.3	-1.2	-1.0	-1.8	-1.3	-0.6	-0.6	-0.4	-1.3	-0.8	-1.0	-1.2	-0.5	1.0	-0.3	-0.1	-1.4	0.0	-0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.9	0.3	0.8	1.4	0.7	1.1	0.4	0.4	0.9	0.1	0.0	0.9	1.0	0.7	-0.9	-0.9	-0.7	-0.6	0.4
Medication: Ramipril	1.6	2.0	7.9	1.7	1.0	0.9	1.4	0.4	0.7	0.3	1.3	1.6	1.0	1.5	1.6	-2.8	1.1	2.6	1.2	1.2	1.1
Medication: Simvastatin	0.2	0.3	1.3	0.4	0.0	-0.5	-0.1	-1.0	0.1	-0.0	0.0	0.2	0.0	0.6	0.8	-1.1	0.8	0.9	0.6	0.2	0.0
Fluid intelligence score	1.6	3.3	10.3	2.0	2.1	1.0	1.4	1.2	2.1	1.9	1.9	1.9	1.6	1.5	3.2	-1.7	2.0	1.2	1.1	2.0	1.8
Illnesses of siblings	1.2	1.7	11.3	-1.1	-0.2	1.4	0.6	-0.9	-1.0	-1.0	0.2	-0.1	-0.0	0.1	0.7	2.1	-3.4	-1.5	-0.8	-1.5	-1.5
Neuroticism score	1.1	2.3	7.1	-1.5	-1.4	-1.2	-2.0	-1.3	-0.8	-0.5	-1.7	-2.0	-1.7	-1.6	-2.7	1.8	-1.4	-1.2	-0.9	-0.7	-1.2
Weight	0.5	2.5	8.4	1.3	1.6	1.9	1.6	-0.6	1.0	0.8	2.0	1.5	2.9	2.3	1.7	-1.9	1.2	1.0	1.4	0.9	1.1
Impedance of arm (right)	0.1	0.7	2.3	0.6	0.6	-0.1	-0.4	1.2	1.2	1.3	0.0	0.8	0.3	-0.1	0.8	0.3	0.4	0.3	-0.7	1.5	1.5
Arm fat percentage (right)	1.0	3.8	9.0	1.8	1.9	2.3	1.5	-0.1	1.3	1.1	2.0	2.4	3.0	2.6	2.0	-2.3	1.9	2.0	1.5	1.7	1.9
Trunk fat-free mass	0.1	0.5	2.2	0.5	0.7	0.7	1.0	-0.3	0.2	0.1	1.1	-0.3	1.5	1.0	0.9	-0.9	0.4	-0.0	1.1	-0.1	-0.2
Hip circumference	0.8	3.3	9.8	1.7	1.9	2.1	1.3	-0.9	1.5	1.3	2.1	2.0	3.1	2.3	2.1	-1.6	1.5	1.1	1.5	1.4	1.6
Time employed in main current job	0.8	0.9	2.5	0.2	0.3	-0.9	-1.5	-0.6	1.3	1.6	-0.5	1.4	0.4	-0.4	-1.1	0.9	0.2	-0.5	0.1	1.3	1.3
Alcohol intake versus 10 years previously	0.2	0.3	1.0	-0.7	0.0	0.7	-0.0	-0.6	-0.0	0.1	-0.1	-0.4	0.0	-0.0	-0.6	0.8	0.8	-1.0	-1.0	-0.4	-0.0
Father’s age at death	0.5	0.7	4.5	-0.4	-0.0	-0.6	-0.8	-0.2	0.5	0.6	-0.4	-1.0	0.2	-0.7	-0.5	2.1	-0.2	-1.8	-0.2	-0.3	-0.0
Worrier / anxious feelings	0.9	1.7	8.5	-0.8	-0.9	-1.1	-2.9	-1.0	0.6	1.0	-2.0	-0.9	-1.1	-1.7	-1.6	1.5	-1.1	-1.3	0.0	0.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	7.3	-1.2	-1.1	-0.7	-1.7	-0.8	-0.7	-0.5	-1.3	-2.0	-0.8	-0.9	-2.7	2.0	-0.2	-1.6	-1.0	-1.1	-0.5
Falls in the last year	0.7	1.0	8.0	0.5	1.0	2.8	0.9	-0.5	0.6	0.6	1.1	0.2	1.7	1.1	-0.2	0.5	0.2	-0.4	0.4	0.2	0.7
Hair/balding pattern: Pattern 3	1.0	1.4	3.4	1.4	1.3	1.5	1.3	-0.0	1.0	0.8	1.4	1.4	1.6	1.1	1.8	-1.0	-0.3	0.7	1.6	0.9	0.7
Number of live births	0.8	1.1	2.9	1.4	1.2	1.5	0.2	-0.1	1.4	1.4	0.9	0.7	1.2	0.8	-1.2	0.7	-0.6	-0.3	1.7	0.6	1.0
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	3.3	-1.1	-0.5	0.4	0.0	-1.1	-0.9	-0.9	-0.2	-1.8	-0.3	-0.1	-0.1	1.5	-0.4	-1.8	-0.6	-1.7	-1.5
Pulse rate	0.3	0.4	1.5	0.2	0.7	-0.1	0.1	-0.8	0.8	0.9	0.5	0.7	1.2	0.7	-0.0	0.7	0.8	-1.1	0.3	0.1	0.4
Happiness	0.5	0.7	2.4	0.6	0.2	-0.4	0.7	-1.5	-0.3	-0.5	0.5	-1.5	-0.3	0.2	-1.6	0.0	-1.2	0.1	0.2	-1.0	-0.7
Noisy workplace	0.4	0.5	4.0	-0.2	-0.5	-0.6	-0.5	-0.1	-0.2	-0.3	-0.6	0.3	0.6	-0.4	-2.0	-0.7	0.2	1.1	0.8	0.9	0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.3	-0.5	-0.7	-1.8	0.2	-0.3	-0.9	-1.0	-0.5	-1.5	-0.8	-0.9	1.1	-0.2	-1.2	-0.2	-0.8	-1.2	-1.3
Serious illness, injury or assault of a close relative in last 2 years	4.3	4.9	9.5	2.6	2.7	2.6	2.1	-1.1	2.2	1.9	2.7	1.8	2.4	2.7	1.0	-1.8	2.1	1.9	3.1	2.2	1.8
Mouth/teeth dental problems: Dentures	0.2	0.3	1.5	0.2	0.2	0.3	0.1	0.3	0.1	0.1	0.1	0.6	0.5	0.2	0.3	-1.1	1.2	1.0	0.9	0.7	0.4
Asthma	1.7	3.4	8.6	2.0	2.1	2.9	1.3	2.3	2.0	1.9	2.0	2.0	2.0	2.0	0.7	-0.9	0.9	0.9	1.0	1.8	2.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.9	-0.6	-0.3	0.3	-0.6	-0.8	-0.2	-0.2	-0.3	-0.1	0.2	-0.4	-0.1	0.9	0.9	-0.1	-0.7	-0.1	0.2
Medication: Cholesterol lowering	1.4	2.2	3.9	1.5	1.5	0.4	0.1	-1.0	2.0	2.0	1.0	1.4	1.3	1.8	1.5	-1.1	1.7	0.9	1.8	1.9	1.9
Depression (self-reported)	0.8	1.0	4.2	-0.9	-1.0	-1.3	-1.5	-0.0	-0.6	-0.5	-1.2	-2.0	-0.7	-1.2	-1.4	0.6	0.9	-0.2	-0.3	-0.5	-0.4
Medication: Lansoprazole	1.0	1.2	3.7	1.4	1.0	0.9	0.7	1.9	1.2	1.2	0.7	1.1	1.5	0.9	-1.2	-0.7	0.2	0.7	0.6	1.2	1.1
Prospective memory result	2.6	3.2	7.5	-2.2	-1.6	-0.9	-1.3	-1.9	-1.6	-1.5	-1.4	-1.9	-1.8	-1.3	-2.7	2.1	-1.0	-2.5	-1.5	-2.0	-1.7
Lung cancer (father)	0.5	0.5	2.7	0.0	0.0	-0.9	-0.2	1.6	0.1	0.1	-0.1	-0.3	1.0	-0.1	-0.1	-0.7	1.6	0.5	1.2	0.2	0.1
Illnesses of mother	6.5	8.0	15.3	3.4	2.9	2.0	1.5	1.5	3.2	3.0	2.4	3.0	2.5	2.4	2.8	-3.0	2.9	3.0	3.1	3.9	3.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	3.0	-0.8	-0.1	0.2	0.1	-1.2	-0.5	-0.4	0.1	-1.5	0.1	0.1	-0.1	1.7	0.3	-1.7	-0.3	-1.3	-1.2
Pulse wave Arterial Stiffness index	1.8	2.1	4.6	1.9	1.5	0.9	0.8	-0.4	1.6	1.4	1.3	1.5	1.5	1.4	1.3	-2.1	1.1	1.6	2.1	1.2	1.5
Impedance of arm (left)	0.1	0.6	1.7	0.7	0.8	0.2	0.2	0.7	1.0	1.1	0.4	1.0	0.1	0.3	1.0	0.3	0.1	0.5	-0.7	1.3	1.2
Arm fat mass (right)	0.7	2.8	7.5	1.4	1.5	1.9	1.3	-0.5	1.0	0.8	1.8	2.0	2.7	2.3	1.8	-2.2	1.6	1.7	1.4	1.2	1.5
Trunk predicted mass	0.1	0.5	1.8	0.4	0.6	0.6	1.0	-0.2	0.1	-0.0	1.0	-0.4	1.4	0.8	0.9	-1.0	0.4	-0.0	1.0	-0.2	-0.3
Standing height	0.0	0.4	1.8	0.6	0.9	0.2	0.6	0.8	0.7	0.7	0.9	-0.2	1.0	0.5	1.3	-0.8	-0.3	-0.3	0.3	0.4	0.4
Length of working week for main job	1.0	1.1	3.0	1.1	1.2	0.5	-0.1	-1.4	1.6	1.7	0.8	0.8	1.7	0.8	0.4	0.2	0.6	0.2	1.1	1.2	1.3
Exposure to tobacco smoke at home	0.8	0.9	2.4	-0.7	-0.8	-0.6	-0.9	-1.6	-0.9	-1.0	-0.5	-1.2	-0.7	-0.9	-1.2	1.3	-0.1	-1.1	-0.2	-1.4	-1.0
Breastfed as a baby	0.3	0.3	1.6	0.3	-0.1	0.3	0.1	0.3	-0.1	-0.2	0.0	0.8	0.3	0.1	-1.3	-1.1	-0.2	1.1	0.8	0.0	0.4
Tense / ‘highly strung’	1.0	1.6	4.7	-1.3	-1.2	-1.6	-2.2	-1.9	-0.3	-0.0	-1.8	-0.8	-1.0	-1.0	-1.6	1.7	-1.1	-1.4	-0.1	-0.3	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	6.8	-2.6	-2.2	-1.8	-2.3	-0.9	-2.0	-1.7	-2.2	-1.9	-1.8	-1.9	-2.5	2.3	-0.8	-2.0	-2.2	-2.1	-1.6
Hair/balding pattern: Pattern 4	0.4	1.0	5.3	-0.6	-0.7	-0.2	-0.1	-2.3	-0.9	-0.9	-0.5	-1.9	-0.9	-0.1	-1.0	0.5	-1.1	-0.3	-1.0	-1.5	-0.9
Birth weight of first child	1.1	2.0	3.7	1.9	1.8	1.4	1.7	0.0	1.5	1.3	1.9	1.2	1.8	1.7	0.3	-1.0	0.8	1.2	1.3	1.6	1.6
Peak expiratory flow (PEF)	0.3	0.7	3.2	-0.3	0.0	0.8	-0.1	-1.7	-0.1	-0.1	0.1	-0.5	0.3	0.4	1.8	1.1	0.0	-1.2	-0.4	-1.0	-0.6
Pulse wave reflection index	0.2	0.3	1.0	0.1	-0.4	-0.4	-0.9	0.1	-0.0	-0.0	-0.7	-0.0	-0.9	-0.6	1.0	-0.5	-0.5	0.4	0.2	-0.1	0.1
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.3	-1.2	-1.1	-1.1	-0.7	-1.8	-1.0	-0.8	-1.1	-1.1	-0.9	-0.5	-1.2	1.3	-1.0	-0.6	-0.4	-0.9	-1.3
Loud music exposure frequency	0.9	1.0	3.1	-0.4	-0.6	-0.4	0.8	0.6	-1.3	-1.5	0.0	-1.8	-1.2	-0.4	-1.4	-0.3	-0.7	0.0	-1.0	-1.6	-1.5
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.0	0.9	1.2	1.1	1.7	-0.7	0.6	0.5	1.5	-0.3	1.3	1.0	1.5	-0.7	-0.2	0.7	-0.0	0.2	0.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	3.7	0.2	0.2	0.1	-0.4	-1.9	0.3	0.3	0.1	0.0	0.5	-0.0	0.4	0.5	-1.0	-0.6	-0.7	-0.0	0.2
Blood clot in the leg (DVT)	0.4	0.5	1.5	0.7	0.6	-0.2	-0.5	0.2	1.0	1.1	0.1	0.5	1.0	0.3	-0.4	-0.7	-0.6	0.6	0.7	1.2	1.1
Medication: Paracetamol	0.5	0.8	3.6	-0.6	-0.7	-0.5	-1.9	0.2	0.2	0.5	-1.4	0.2	-0.2	-0.8	-1.5	1.5	0.5	-0.7	-0.8	0.5	0.4
Headache pain in last month	0.5	0.8	3.3	-1.0	-0.5	-1.2	-1.1	-0.8	-0.3	-0.1	-0.6	-0.3	-0.4	-0.6	-0.3	1.8	1.3	-1.5	-0.8	-0.4	-0.4
Medication for cholesterol, blood pressure or diabetes	1.9	3.1	8.0	-1.7	-1.9	-1.3	-1.3	-0.5	-1.7	-1.6	-1.8	-2.2	-1.8	-2.8	-1.4	1.5	-1.9	-1.4	-1.8	-2.0	-1.7
Glaucoma (self-reported)	0.6	0.7	3.7	0.8	0.7	0.2	0.2	-1.9	0.8	0.8	0.5	0.2	0.6	0.8	1.4	-0.2	0.9	0.3	1.2	0.7	0.8
Gout (self-reported)	0.9	1.2	4.0	1.2	1.2	0.5	0.5	-0.1	1.2	1.1	1.0	1.2	0.6	1.0	2.0	-1.0	1.4	0.8	0.6	1.4	1.6
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	11.2	0.5	0.3	1.1	1.7	3.3	-0.6	-0.9	1.1	-0.6	-0.2	0.5	0.7	-2.1	0.9	1.4	-0.1	-0.1	-0.3
Medication: Amlodipine	0.4	0.5	1.3	-0.9	-0.9	-0.4	-0.8	-0.3	-0.8	-0.7	-0.9	-0.6	-0.9	-0.8	-0.5	0.8	-0.4	-0.3	-1.1	-0.7	-0.7
Medication: Ventolin 100micrograms inhaler	3.1	4.0	11.1	2.0	2.2	3.3	1.4	2.1	1.9	1.8	2.1	2.3	2.0	1.6	0.5	-1.5	1.2	1.4	2.2	2.0	2.6
Birth weight	0.8	1.7	6.8	-1.1	-1.7	-2.6	-1.9	-0.4	-1.0	-0.9	-1.9	-1.2	-1.7	-2.2	-0.6	0.5	-0.4	-0.1	-0.3	-0.6	-0.8
Chronic bronchitis/emphysema (mother)	0.7	0.8	4.8	0.6	0.9	-1.1	0.1	0.9	1.0	1.0	0.7	-0.1	0.9	0.9	0.6	-0.1	2.2	0.1	0.4	0.8	1.1
High blood pressure (siblings)	0.4	0.6	5.3	0.5	0.2	-0.9	-0.4	0.4	0.7	0.8	-0.2	-0.5	-0.0	-0.4	-0.7	-0.4	2.3	0.4	0.3	0.9	0.9
Forced vital capacity (FVC), Best measure	0.1	0.3	1.9	-0.3	0.1	0.4	0.5	-0.3	-0.4	-0.4	0.4	-1.4	-0.1	0.1	-0.0	0.7	0.2	-1.0	-0.1	-1.0	-0.8
Body fat percentage	1.5	6.1	12.0	2.4	2.5	2.6	2.0	0.0	1.9	1.6	2.7	3.1	3.5	3.3	2.2	-2.8	2.4	2.4	2.3	2.2	2.5
Leg fat percentage (right)	0.9	3.4	9.1	1.6	1.9	2.3	1.6	-0.2	1.4	1.2	2.1	2.1	3.0	2.6	1.4	-1.5	2.3	1.1	1.6	1.2	1.6
Arm fat-free mass (right)	0.2	0.8	2.8	0.7	0.8	0.7	1.2	0.1	0.2	0.0	1.2	0.2	1.6	1.3	0.6	-1.5	0.5	0.5	1.7	0.0	0.0
Exposure to tobacco smoke outside home	2.0	2.7	6.4	-1.9	-2.1	-1.7	-2.5	-0.3	-1.4	-1.1	-2.4	-1.7	-1.3	-2.2	-1.9	1.4	-1.0	-1.4	-1.2	-1.2	-1.3
Comparative body size at age 10	0.3	0.9	5.2	-0.2	-0.8	-2.2	-1.0	-2.3	-0.4	-0.4	-0.9	-0.2	-0.6	-0.7	1.4	-0.5	-0.4	0.5	-0.1	-0.4	-0.5
Number of full brothers	0.4	0.5	1.5	-0.4	-0.5	0.1	0.2	1.2	-0.8	-1.0	-0.2	0.0	-0.1	-0.7	-0.8	0.5	-0.9	-0.7	-1.0	-0.9	-0.4
Worry too long after embarrassment	0.2	0.3	0.9	-0.1	-0.2	-0.3	-0.6	-0.7	0.1	0.2	-0.4	-0.9	-1.0	-0.8	-0.8	-0.1	-0.4	0.3	0.2	0.3	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	5.0	-1.1	-0.9	-1.4	-1.6	-1.9	-0.4	-0.2	-1.4	-2.2	-0.8	-1.1	-2.1	2.1	-1.1	-1.8	-0.3	-1.2	-0.9
Wheeze or whistling in the chest in last year	0.3	0.6	2.5	0.6	0.5	1.2	-0.4	0.6	0.6	0.5	0.4	1.6	0.4	0.6	0.0	-0.8	-0.0	0.5	1.2	0.5	1.0
Number of children fathered	0.6	0.7	3.2	0.9	1.0	1.1	1.5	-0.3	0.8	0.8	1.1	0.6	1.8	0.7	-0.3	-0.2	-0.1	-0.2	0.8	0.4	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.9	0.2	-0.2	0.0	0.9	0.7	-0.6	-0.8	0.2	-0.2	-0.4	-0.1	-0.1	-1.0	-0.8	0.4	-0.3	-0.6	-0.1
Age at first live birth	0.6	1.1	5.4	0.0	-0.6	-0.4	1.1	1.2	-1.3	-1.7	0.1	-1.0	-0.8	-0.3	-0.3	-1.3	-2.3	1.1	-0.5	-0.9	-1.3
Pulse wave peak to peak time	1.6	1.9	4.4	-1.8	-1.4	-0.9	-0.8	0.3	-1.4	-1.3	-1.2	-1.4	-1.5	-1.4	-1.1	2.1	-0.9	-1.6	-2.0	-1.1	-1.4
Health satisfaction	0.6	0.8	6.8	0.3	0.3	1.1	1.3	0.3	-0.4	-0.6	0.7	-0.3	0.8	0.6	-2.6	-0.0	0.4	0.2	0.9	-0.6	-0.5
Shortness of breath walking on level ground	1.2	1.5	3.9	0.8	1.2	1.9	2.0	0.3	0.2	-0.0	1.7	1.0	2.0	1.7	-1.1	-0.7	-0.3	0.7	1.9	0.3	0.3
Qualifications: College or University degree	0.5	1.6	8.1	-0.8	-1.1	-2.9	-0.6	-0.4	-0.9	-0.9	-1.1	-1.9	-1.5	-0.9	-0.4	0.3	-2.1	-0.3	-0.3	-1.4	-1.5
Eye problems/disorders: None of the above	0.5	0.6	1.8	-0.6	-0.8	-0.4	0.2	-0.5	-1.2	-1.3	-0.3	0.1	-0.5	-0.8	0.5	-0.4	-1.3	0.2	-0.7	-0.8	-1.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.3	-0.3	-0.5	-0.1	0.4	0.2	-1.0	-1.2	0.0	-0.5	-0.3	-0.3	-0.3	-0.4	-0.6	0.6	-0.7	-1.0	-1.1
Emphysema/chronic bronchitis	1.7	1.9	3.9	1.6	1.4	1.6	1.4	1.1	1.0	0.7	1.5	1.3	1.7	1.8	0.6	-1.6	0.3	1.5	2.0	0.9	1.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.3	-0.0	-0.2	-0.5	0.0	-1.1	-0.3	-0.3	-0.1	-0.8	-0.6	-0.4	0.3	-0.6	-1.0	-0.1	0.3	-0.4	-0.5
Neck or shoulder pain in last month	0.1	0.1	0.6	0.1	0.0	-0.1	0.5	0.4	-0.0	-0.1	0.1	-0.5	0.2	-0.1	-0.5	0.0	-0.1	0.5	0.8	0.0	-0.1
Medication: Blood pressure	1.1	1.9	6.1	1.1	1.5	1.2	1.8	0.1	0.9	0.8	1.8	2.0	1.7	2.5	1.5	-0.9	1.0	0.8	1.0	1.2	0.7
Angina (self-reported)	1.7	2.2	4.0	1.8	1.6	1.1	1.9	-0.1	1.0	0.8	2.0	1.6	1.4	2.0	1.1	-1.4	1.2	1.8	2.0	1.3	1.2
Migraine (self-reported)	0.3	0.4	3.2	0.3	0.5	-0.6	-0.3	-0.6	0.7	0.8	0.1	-0.2	0.6	0.8	-0.1	0.3	1.8	0.0	0.7	0.6	0.1
Medication: Ibuprofen	0.2	0.2	0.9	-0.3	-0.1	0.7	-0.2	-0.8	-0.3	-0.3	0.1	-0.1	0.3	-0.2	-0.2	0.8	0.5	-0.3	-0.9	-0.3	-0.0
Medication: Allopurinol	1.6	2.1	4.3	0.9	1.6	1.5	0.8	1.2	1.7	1.8	1.3	1.9	1.9	1.3	1.6	-0.1	2.0	-0.2	1.0	1.5	2.1
Medication: Omeprazole	0.9	1.0	4.0	0.1	0.7	1.3	2.0	1.8	-0.3	-0.5	1.4	0.3	1.2	1.1	-1.0	0.3	0.2	-0.8	0.7	-0.8	-1.0
Medication: Seretide 50 evohaler	1.2	1.4	7.2	0.9	1.0	0.5	0.1	2.7	1.2	1.3	0.6	1.7	0.3	1.4	1.1	-0.9	1.5	0.6	0.8	1.1	1.3
Mean time to correctly identify matches	2.3	4.3	9.6	-2.7	-2.0	-0.9	-1.9	-0.9	-1.7	-1.4	-2.1	-1.0	-1.8	-2.1	-3.1	2.8	-1.7	-2.6	-2.7	-2.3	-1.9
Heart disease (mother)	1.1	1.3	5.6	-1.2	-0.8	-0.5	-0.6	-2.4	-0.9	-0.8	-0.7	-1.2	-1.0	-0.2	-0.8	1.5	-1.6	-1.5	-0.8	-1.6	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.7	3.2	7.2	2.0	2.0	2.0	0.8	0.6	2.3	2.3	1.6	1.0	2.1	1.8	0.8	-1.3	1.4	1.1	2.7	2.1	2.5
Whole body fat mass	1.4	6.0	13.2	2.4	2.5	2.5	2.1	-0.1	1.8	1.6	2.7	2.9	3.6	3.3	2.3	-3.0	2.2	2.4	2.4	2.1	2.3
Leg fat mass (right)	0.9	3.3	9.7	1.6	1.8	2.0	1.4	-0.3	1.3	1.1	2.0	2.2	3.1	2.7	1.6	-2.0	1.9	1.4	1.8	1.3	1.6
Arm predicted mass (right)	0.2	1.3	3.7	1.0	1.1	1.0	1.2	0.2	0.6	0.5	1.4	0.5	1.8	1.6	1.0	-1.7	0.9	0.6	1.9	0.3	0.4
Pulse rate, automated reading	0.5	1.7	5.2	1.2	1.6	1.3	2.0	1.0	0.9	0.8	1.9	1.3	2.0	2.3	0.3	-0.1	1.0	0.1	1.0	0.4	0.8
Alcohol intake frequency.	0.2	0.5	1.3	-1.0	-0.7	0.1	-0.9	-0.6	-0.6	-0.5	-0.8	0.1	-0.5	-0.7	-0.3	1.1	0.1	-1.1	-0.8	-0.8	-0.7
Comparative height size at age 10	0.0	0.2	1.3	0.1	0.5	0.1	0.1	-0.2	0.6	0.7	0.3	-0.4	1.1	0.1	-0.4	-0.3	-0.3	-0.3	0.5	0.1	0.6
Number of full sisters	0.5	0.6	2.8	0.6	0.5	0.1	-0.3	-1.0	1.0	1.1	0.2	1.0	0.5	-0.2	1.1	-0.2	1.7	-0.1	-0.1	1.1	0.8
Suffer from ‘nerves’	3.6	5.6	9.9	-2.9	-2.8	-2.5	-2.5	0.2	-2.0	-1.7	-3.1	-2.5	-2.7	-2.4	-2.3	3.1	-1.3	-2.6	-2.2	-2.2	-2.0
Overall health rating	0.4	0.9	3.8	-0.9	-0.2	1.2	0.4	-0.8	-0.8	-0.8	0.2	-0.3	0.4	0.7	-2.0	1.6	-0.1	-1.3	-0.7	-1.1	-0.5
Chest pain or discomfort	2.1	3.0	5.7	1.6	2.0	2.2	1.9	1.1	1.4	1.2	2.2	1.7	2.3	2.4	0.6	-1.1	1.9	1.5	1.8	1.5	1.7
Had major operations	2.0	2.3	4.6	-1.5	-2.1	-1.6	-1.1	1.1	-1.9	-2.0	-1.9	-1.6	-2.2	-2.0	-0.6	-0.1	-1.4	-0.0	-0.9	-1.7	-1.2
Age at last live birth	0.3	0.4	3.8	0.1	-0.2	0.5	0.4	0.4	-0.6	-0.7	0.1	-0.6	-0.5	0.3	-0.9	-0.3	-1.9	0.2	-0.1	-0.7	-0.8
Family relationship satisfaction	0.8	1.0	1.7	-0.1	-1.1	-0.9	-1.3	-1.1	-0.7	-0.9	-1.2	-0.8	-1.1	-1.3	-1.3	-0.3	-1.3	0.8	0.3	-1.0	-0.7
Leg pain on walking	0.6	0.8	2.4	0.4	0.9	1.4	0.1	-0.9	1.1	1.1	0.5	-0.2	1.4	0.4	-1.6	0.5	0.6	-0.5	1.2	0.6	0.5
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.5	0.9	1.0	1.7	0.7	-1.5	0.7	0.7	1.2	2.1	1.6	1.1	1.2	-0.7	1.0	1.0	0.2	1.1	0.6
Commuting to job workplace: Car/motor vehicle	4.7	5.4	14.3	2.8	2.0	1.4	2.0	0.6	1.7	1.3	2.1	3.4	2.1	2.1	1.9	-3.8	1.1	3.7	2.9	2.4	1.9
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	4.7	-0.1	0.0	-0.7	0.7	0.3	-0.2	-0.2	0.2	-0.1	0.1	0.3	2.2	0.2	-0.6	-0.5	-0.8	-0.2	-0.6
Medication: Aspirin	1.3	1.8	3.4	1.3	1.4	1.0	1.4	1.1	1.3	1.2	1.4	1.8	1.0	1.5	1.8	-0.6	1.2	1.2	1.2	1.3	1.6
Supplements: Vitamin C	0.5	0.5	4.6	0.2	0.7	0.3	0.8	2.1	0.5	0.6	0.6	-0.3	0.1	0.6	0.3	-0.1	1.4	-0.5	-0.2	0.3	0.4
Knee pain experienced in last month	0.3	0.4	2.7	-0.2	-0.0	0.6	-0.4	-0.6	-0.1	-0.0	0.0	-1.0	0.5	0.0	-1.7	0.9	-0.1	-0.7	-0.5	-0.8	-0.3
Hypertension (Self-reported)	0.2	0.4	2.0	0.2	0.3	0.5	0.8	-1.4	-0.1	-0.2	0.6	0.5	0.6	1.2	-0.3	-1.0	0.6	0.5	0.3	0.1	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.4	6.2	1.2	1.1	2.1	1.4	2.5	0.7	0.6	1.3	2.2	1.8	1.5	-1.7	-1.3	0.8	1.7	2.1	1.3	0.7
Illnesses of father: Heart disease	0.9	1.2	3.5	-0.9	-1.1	-0.9	-0.9	-0.4	-1.0	-1.0	-0.9	-0.7	-1.5	-1.2	1.9	1.1	-1.3	-1.0	-1.0	-1.4	-0.9
Illnesses of siblings: Diabetes	0.7	0.9	4.3	0.1	-0.6	-2.0	-1.3	0.1	0.1	0.0	-1.0	-0.3	-0.9	-0.9	-2.1	-0.7	1.3	0.8	0.3	0.6	0.1
Smoking status: Previous	0.4	0.6	3.9	0.7	-0.2	-0.1	0.4	0.6	-0.3	-0.5	0.1	-0.1	-0.1	0.1	1.0	-1.9	-0.4	2.0	0.5	0.4	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.8	0.1	0.6	0.5	0.8	0.4	0.2	0.2	0.8	-0.3	0.9	0.7	-0.4	-0.4	0.2	0.1	0.5	0.6	0.1
Whole body fat-free mass	0.1	0.6	2.6	0.5	0.7	0.6	0.9	-0.4	0.3	0.1	1.0	-0.1	1.6	1.2	1.1	-1.0	0.5	0.1	1.1	0.0	-0.1
Leg fat-free mass (right)	0.1	0.7	2.7	0.5	0.7	0.4	0.7	-0.7	0.3	0.2	0.9	0.1	1.6	1.3	1.4	-1.3	0.3	0.5	0.9	0.3	0.2
Arm fat percentage (left)	1.0	3.9	8.8	1.8	1.9	2.4	1.8	-0.2	1.2	0.9	2.2	2.5	3.0	2.8	2.1	-2.2	1.7	2.1	1.4	1.5	1.7
Average weekly red wine intake	0.3	0.4	2.7	-0.3	-0.2	0.2	0.6	1.6	-0.6	-0.6	0.1	-0.0	-0.2	-0.3	-0.1	-0.0	-1.3	-0.7	-0.8	-0.7	-0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.6	-0.8	-1.0	-0.9	-1.3	-0.3	-0.8	-0.8	-1.1	0.4	-0.7	-1.0	-0.4	-0.3	0.1	0.7	-0.7	-0.3	-0.4
Mood swings	0.8	1.4	4.9	-1.4	-0.4	-0.8	-1.5	-2.1	-0.3	0.1	-0.6	-1.0	-0.5	-0.2	-1.7	2.2	-0.7	-1.7	-1.4	-0.4	-0.5
Loneliness, isolation	0.4	0.5	3.1	-0.7	-0.6	0.0	-1.1	1.0	-0.3	-0.2	-0.8	-0.8	-0.4	-0.6	-1.8	1.0	0.4	-0.5	0.1	-0.1	0.1
Long-standing illness, disability or infirmity	0.6	0.9	2.8	0.7	1.2	1.7	1.1	-0.4	0.8	0.7	1.3	0.9	1.5	1.5	-1.0	0.3	0.7	-0.5	0.7	0.3	0.5
Ever had bowel cancer screening	2.9	3.4	6.3	-1.8	-1.9	-1.9	-2.2	-1.8	-1.5	-1.3	-2.0	-1.8	-1.4	-2.2	-1.3	1.9	-2.5	-2.0	-1.5	-2.0	-1.5
Diabetes diagnosed by doctor	1.1	1.8	5.3	-1.7	-1.4	-2.3	-1.7	-0.6	-1.0	-0.8	-1.7	-1.3	-1.3	-1.6	-1.2	1.5	-0.5	-0.6	-2.1	-0.5	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.5	0.3	0.0	0.5	0.2	0.8	-0.2	-0.4	0.2	0.6	-0.5	0.1	0.3	-1.2	-0.4	0.8	0.5	-0.2	-0.4
Friendships satisfaction	0.3	0.4	1.0	0.7	0.8	-0.1	0.0	-0.2	1.0	1.0	0.5	-0.3	0.7	0.3	-0.8	0.6	-0.1	-0.3	1.0	0.2	0.6
Qualifications: nursing, teaching	0.3	0.4	1.4	0.2	-0.0	-0.2	1.1	0.2	-0.7	-0.9	0.6	-0.4	0.5	-0.3	0.2	-1.2	-0.8	0.6	-0.0	-0.6	-1.0
Commuting to job workplace: Walk	0.6	0.6	1.7	-0.9	-0.4	-0.1	-0.1	-1.3	-0.6	-0.5	-0.4	-1.1	-0.7	-0.7	-0.3	1.0	-1.0	-1.1	-1.3	-0.7	-0.5
Eye problems/disorders: Cataract	0.8	0.9	3.2	1.0	1.1	0.4	-0.0	1.8	1.3	1.3	0.7	0.2	0.8	0.9	-0.5	-0.2	1.4	0.1	0.5	0.9	1.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.8	-0.8	-0.3	-0.4	-0.2	-0.7	-0.5	-0.4	-0.2	-1.7	-0.7	-0.6	-0.2	1.4	0.3	-1.5	-1.0	-1.0	-0.7
Medication for cholesterol	1.9	2.8	4.8	2.2	2.0	1.4	2.0	1.8	1.9	1.7	1.9	1.6	1.7	1.5	1.7	-0.9	1.0	1.0	1.8	1.8	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	6.2	1.5	1.6	1.6	1.8	0.2	1.1	0.9	1.8	1.3	1.7	2.5	0.1	-1.1	1.1	0.8	1.8	0.8	0.5
Back pain experienced in last month	0.5	0.7	4.9	0.3	0.5	2.2	0.6	0.3	-0.2	-0.4	1.0	1.1	1.3	0.4	0.6	-0.2	-1.1	0.2	0.4	-0.3	-0.2
Mineral and other dietary supplements	1.6	2.2	4.9	1.7	1.8	1.7	2.1	-1.1	1.2	1.0	1.9	1.5	1.5	2.2	1.6	-1.0	0.0	1.0	1.8	0.8	1.1
Breast cancer (self-reported)	0.5	0.6	4.6	0.6	0.3	-0.1	-0.1	0.3	0.8	0.9	-0.1	0.7	0.3	0.1	0.7	-0.7	2.1	0.6	0.9	0.7	1.1
Asthma (self-reported)	1.8	3.6	8.8	2.0	2.2	3.0	1.1	2.3	2.1	2.0	2.0	2.1	2.0	1.9	0.6	-0.8	1.1	0.7	1.0	1.9	2.9
Osteoporosis (self-reported)	1.5	1.9	3.6	-1.5	-1.3	-0.9	-1.6	-1.9	-0.8	-0.6	-1.7	-1.7	-1.5	-1.1	-0.5	1.4	-1.8	-1.7	-1.4	-1.1	-1.0
Osteoarthritis (self-reported)	0.2	0.3	1.5	0.4	0.3	0.5	0.5	0.1	-0.1	-0.2	0.6	1.2	0.8	0.2	-0.2	-0.8	-0.3	1.1	0.1	0.5	0.3
Medication: Aspirin	0.5	0.6	1.5	0.6	0.8	0.7	1.0	0.7	0.6	0.6	0.9	1.2	0.6	0.9	1.2	0.1	0.5	0.6	0.7	0.6	0.9
Medication: Gliclazide	0.5	0.5	2.7	-1.0	-0.5	-0.5	-0.0	1.6	-1.0	-1.0	-0.1	-0.4	-0.6	0.0	-0.5	0.5	-0.2	-0.5	-1.1	-0.9	-0.5
Illnesses of father: None of the above (group 1)	0.2	0.3	1.3	-0.3	-0.3	0.2	-0.6	0.3	-0.1	-0.0	-0.5	0.8	0.3	-0.4	-1.1	-0.5	0.3	0.8	0.4	0.7	0.2
Smoking status: Current	0.4	0.6	2.2	-0.2	-0.5	0.8	0.6	-1.1	-1.2	-1.5	0.2	0.4	-0.1	-0.0	-0.8	0.6	-0.8	0.2	-0.1	-1.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.3	-0.3	0.1	-0.4	-0.3	-0.8	0.1	0.2	-0.0	-0.5	-0.5	0.0	0.0	0.7	1.1	-0.8	0.1	-0.2	-0.2
Whole body water mass	0.1	0.7	2.6	0.5	0.8	0.7	1.0	-0.3	0.3	0.2	1.1	-0.1	1.6	1.2	1.2	-1.1	0.5	0.1	1.2	0.0	-0.0
Leg predicted mass (right)	0.1	0.8	2.8	0.6	0.8	0.4	0.8	-0.7	0.4	0.2	1.0	0.1	1.7	1.4	1.3	-1.4	0.2	0.6	1.0	0.4	0.2
Arm fat mass (left)	0.7	3.0	7.6	1.4	1.6	2.1	1.7	-0.4	0.8	0.6	2.0	2.1	2.8	2.5	1.9	-2.2	1.5	1.8	1.5	1.1	1.2
Number of self-reported non-cancer illnesses	0.6	1.1	2.7	1.1	1.2	1.5	0.9	0.5	0.9	0.8	1.3	1.3	1.1	1.7	-0.6	-0.9	1.1	0.7	0.1	0.8	1.2
Average weekly champagne plus white wine intake	0.5	0.7	3.9	0.0	0.6	0.3	-0.7	-2.0	0.9	1.0	0.2	1.4	1.2	-0.1	0.9	-0.2	-0.4	-0.4	0.6	0.8	0.7
Miserableness	0.4	0.7	1.9	0.7	1.1	0.8	0.3	-0.3	1.1	1.2	0.9	0.1	1.1	0.9	-0.8	-0.1	0.4	0.5	0.5	1.4	0.8
Guilty feelings	0.3	0.4	1.3	0.8	0.7	0.8	0.4	-0.1	0.5	0.4	0.7	-0.3	0.6	0.7	-0.7	-0.1	0.6	1.1	1.0	0.8	0.3
Wears glasses or contact lenses	0.4	0.4	1.4	0.5	0.0	0.2	-0.9	0.1	0.7	0.7	-0.4	0.6	0.2	-0.7	1.0	-1.2	0.3	0.5	0.5	0.8	1.1
Ever taken oral contraceptive pill	0.1	0.1	0.9	-0.3	0.1	0.4	0.7	0.1	-0.3	-0.3	0.3	-0.3	0.3	0.3	0.4	0.1	-0.9	0.1	-0.1	-0.5	0.1
Hearing aid user	0.6	0.7	2.6	0.2	-0.7	-1.3	-0.5	0.1	-0.8	-0.9	-0.4	-0.5	-0.8	-0.9	-1.4	-1.2	-0.2	1.6	0.2	-0.2	0.1
Mother’s age at death	0.3	0.4	2.1	0.3	0.6	0.3	0.3	-0.2	0.6	0.6	0.5	0.9	0.6	0.2	-1.4	0.3	0.1	-0.4	1.2	0.3	0.3
Financial situation satisfaction	0.7	0.9	2.9	1.5	0.8	1.2	1.3	0.2	0.2	-0.1	1.1	0.6	0.7	1.1	0.1	-1.3	0.2	1.7	1.2	0.4	0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.3	-0.6	-0.9	-0.8	-1.0	0.5	-0.4	-0.3	-1.1	-0.6	-1.1	-0.8	-0.0	-0.3	0.9	0.1	-0.9	-0.4	0.3
Commuting to job workplace: Public transport	2.5	3.0	10.8	-2.0	-1.2	-1.6	-0.8	-0.2	-1.3	-1.0	-1.1	-2.4	-0.7	-1.5	-1.2	2.9	-1.0	-3.3	-1.3	-2.2	-2.0
Eye problems/disorders: Glaucoma	0.2	0.2	1.2	-0.3	-0.2	-0.4	-0.8	-1.1	0.1	0.2	-0.5	-0.6	-0.4	-0.0	0.8	0.5	0.3	-0.4	0.3	0.0	0.4
Medication: Blood pressure	0.9	1.6	4.5	-1.1	-1.3	-0.5	0.1	-0.5	-1.9	-2.1	-0.6	-1.9	-1.0	-0.5	-1.9	-0.6	-0.3	0.3	-0.8	-1.8	-2.0
Pain type(s) experienced in last month: Hip pain	1.4	1.7	7.5	0.8	1.1	2.6	2.7	0.4	-0.3	-0.7	2.1	0.8	1.6	2.0	0.5	-0.7	-0.5	0.9	0.7	-0.4	-0.3
Supplements: Fish oil (including cod liver oil)	1.7	2.2	6.7	-1.6	-1.8	-2.4	-2.6	0.9	-1.0	-0.7	-2.1	-1.1	-1.4	-2.4	0.1	1.0	0.5	-0.9	-1.7	-0.4	-0.5
High cholesterol (Self-reported)	0.1	0.2	1.3	-0.1	0.0	-0.4	-0.4	-1.1	0.2	0.2	-0.1	0.3	0.0	0.6	-0.0	-1.0	0.6	0.4	-0.1	0.5	0.3
Medication: Bendroflumethiazide	0.5	0.7	3.5	-0.8	-1.0	-0.8	-0.4	1.2	-1.0	-1.1	-0.7	-0.1	-0.7	-0.6	-1.9	-0.2	-0.4	0.1	-0.2	-0.6	-1.1
Medication: Paracetamol	0.9	1.3	7.9	-1.1	-1.3	-0.4	-1.6	0.4	-0.7	-0.6	-1.6	-0.4	-0.7	-1.4	-2.8	1.4	-0.2	-0.8	-1.0	-0.4	-0.6
Medication: Lisinopril	0.7	0.9	3.7	-0.8	-0.8	0.3	1.0	0.3	-1.7	-1.9	-0.0	0.2	-0.8	0.0	-0.2	-0.0	-0.5	0.1	-0.7	-1.5	-1.7
Medication: Atorvastatin	0.6	0.8	1.5	0.4	1.1	1.2	0.9	-1.2	0.8	0.8	1.2	0.4	0.9	1.0	-0.3	0.8	1.1	-0.8	-0.6	0.1	0.6
Illnesses of father: High blood pressure	1.0	1.2	4.7	0.9	1.4	1.8	2.2	0.8	0.6	0.5	1.7	-0.1	1.4	1.9	0.4	0.1	0.6	-0.6	0.6	-0.2	0.0
Alcohol drinker status: Never	1.2	1.4	3.5	-1.6	-1.0	-0.6	-0.9	0.7	-1.0	-0.7	-0.9	-1.3	-0.4	-1.5	-1.9	1.7	0.2	-1.8	-0.9	-1.2	-1.2
Ever smoked	0.2	0.4	1.1	0.7	0.4	0.7	0.8	0.5	0.0	-0.2	0.6	0.1	0.5	0.5	1.1	-0.8	-0.7	1.0	0.3	0.4	0.2
Basal metabolic rate	0.2	0.9	3.6	0.7	1.0	0.9	1.1	-0.5	0.4	0.3	1.3	0.3	1.9	1.5	1.4	-1.2	0.7	0.3	1.2	0.2	0.2
Leg fat percentage (left)	0.8	3.0	7.7	1.4	1.7	2.1	1.4	-0.0	1.2	1.0	1.9	2.3	2.8	2.4	1.2	-1.8	2.1	1.4	1.6	1.3	1.6
Arm fat-free mass (left)	0.1	0.6	2.2	0.5	0.6	0.6	0.8	0.2	0.1	-0.0	0.9	0.0	1.4	1.0	0.6	-1.5	0.5	0.4	1.3	-0.1	-0.0
Number of operations (self-reported)	0.2	0.3	0.6	-0.5	-0.7	-0.7	-0.7	0.3	-0.5	-0.5	-0.7	-0.1	-0.5	-0.7	-0.6	-0.5	-0.8	0.2	-0.3	-0.7	0.1
Average weekly beer plus cider intake	0.4	0.6	1.5	0.7	0.8	1.2	0.0	-0.6	0.9	0.9	0.7	1.1	0.5	0.7	0.2	-0.1	0.9	0.8	0.5	1.2	1.1
Irritability	0.6	1.1	6.9	-0.8	-0.0	-0.2	-0.3	-2.6	-0.1	0.1	-0.1	-0.8	0.1	-0.3	0.6	1.9	-1.6	-1.6	-1.2	-0.2	-0.6
Risk taking	2.8	4.2	8.2	2.2	2.7	2.0	0.7	-0.0	2.8	2.8	2.2	1.9	2.5	2.2	0.0	-0.6	2.4	0.3	2.0	2.4	2.9
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.5	0.9	1.1	0.2	-0.1	-0.4	1.5	1.6	0.6	1.1	1.0	0.8	-0.0	0.3	0.7	-0.3	1.1	0.9	1.2
Fractured/broken bones in last 5 years	2.0	2.5	6.5	-1.6	-1.6	-0.8	-0.9	-0.6	-1.5	-1.3	-1.6	-2.6	-1.7	-1.3	-0.9	2.1	-1.1	-2.0	-1.6	-2.2	-1.8
Age started oral contraceptive pill	0.3	0.4	2.7	0.4	0.2	0.8	0.1	0.8	0.6	0.6	0.1	0.5	0.7	0.2	0.5	-0.1	-1.6	-1.1	0.0	0.0	0.4
Diastolic blood pressure, automated reading	0.1	0.4	2.1	-0.3	-0.3	-0.3	0.1	-1.1	-0.5	-0.5	-0.2	0.8	0.6	0.0	1.4	-1.0	-0.7	0.6	0.6	0.1	-0.6
Ever depressed for a whole week	0.7	0.9	5.6	-0.8	-0.7	-0.3	-0.5	-0.3	-0.9	-0.9	-0.5	-1.1	-0.8	-0.7	-2.4	0.8	-1.2	-0.3	-0.5	-1.0	-1.0
Unable to work because of sickness or disability	0.2	0.3	1.5	-0.3	-0.0	0.9	0.3	-0.5	-0.3	-0.4	0.2	0.7	0.4	0.4	-1.2	0.7	1.0	-0.2	-0.1	-0.2	-0.1
Commuting to job workplace: Cycle	0.4	0.4	1.3	-0.3	0.6	-0.5	0.2	1.0	0.6	0.8	0.4	0.7	0.3	-0.0	0.4	1.0	1.1	-1.0	0.6	0.6	0.4
Myopia	2.0	3.0	7.2	-1.4	-1.8	-2.3	-1.5	-2.7	-1.6	-1.5	-1.6	-2.1	-1.6	-2.1	-0.6	1.4	-0.7	-1.2	-1.8	-2.0	-1.7
Vascular/heart problems diagnosed by doctor	0.3	0.7	2.6	-0.5	-0.5	-0.8	-1.1	0.9	-0.0	0.1	-0.8	-0.6	-0.8	-1.6	1.0	1.4	-1.1	-1.0	-0.8	-0.3	0.2
Cholesterol lowering medication	0.8	1.2	2.1	-1.5	-1.2	-0.3	-0.6	-1.0	-1.3	-1.3	-0.9	-0.8	-1.1	-1.0	-0.5	1.1	-0.6	-1.2	-1.4	-1.4	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.5	0.4	0.9	1.6	1.9	1.8	-0.0	-0.2	1.4	0.4	1.5	1.2	-1.4	0.2	0.0	-0.6	0.9	-0.6	-0.7
Pain experienced in last month	0.3	0.6	2.3	-0.2	-0.7	-1.5	-0.5	-0.1	-0.3	-0.3	-0.9	-0.3	-1.0	-0.9	1.5	-0.6	-0.9	0.3	0.0	-0.4	-0.1
Supplements: Calcium	0.6	0.7	2.0	-0.7	-0.4	-1.0	-0.8	-0.4	0.1	0.3	-0.8	-1.3	-1.1	-0.5	-1.4	0.9	-0.5	-1.2	-1.0	-0.2	-0.5
Basal cell carcinoma (self-reported)	1.1	1.4	5.3	0.5	1.4	0.4	0.4	0.2	1.4	1.6	1.1	1.1	1.4	1.2	1.3	0.6	2.3	-0.8	0.5	1.2	1.2
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.0	1.1	1.3	0.4	0.4	0.4	1.5	1.6	0.9	0.5	1.1	1.3	1.7	-0.5	1.7	0.7	1.2	1.5	1.6
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.1	0.6	0.5	-0.0	-0.5	-0.1	0.8	0.8	0.1	0.4	0.9	0.2	-0.4	-0.8	-0.9	0.7	0.5	1.0	1.0
Heart disease (siblings)	1.3	1.5	5.2	1.7	1.0	0.5	0.2	0.8	1.5	1.4	0.7	1.4	0.9	0.8	0.7	-2.3	0.8	1.3	0.9	1.4	1.9
Alcohol drinker status: Previous	0.4	0.5	2.3	0.3	-0.6	-0.7	-1.3	-1.0	0.2	0.2	-1.0	0.5	0.0	-0.3	-0.4	-0.2	-1.5	0.6	0.1	0.4	0.5
Pack years of smoking	0.5	0.8	3.6	1.0	0.4	0.8	0.9	-0.5	0.0	-0.2	0.8	0.6	0.8	0.7	0.6	-1.5	0.8	1.9	1.3	0.3	0.7
Impedance of whole body	0.1	0.6	2.5	0.7	0.7	0.1	0.2	1.6	1.0	1.0	0.4	1.2	-0.0	0.1	0.3	-0.0	0.5	0.6	-0.3	1.4	1.3
Leg fat mass (left)	0.8	3.2	8.9	1.5	1.7	1.9	1.4	-0.0	1.1	1.0	1.9	2.3	3.0	2.6	1.5	-2.2	1.8	1.5	1.7	1.3	1.6
Arm predicted mass (left)	0.1	0.7	2.8	0.5	0.6	0.5	0.8	0.1	0.2	0.0	0.9	-0.1	1.4	1.0	0.9	-1.7	0.8	0.5	1.6	0.0	-0.0