Best TWAS P=1.17e-07 · Best GWAS P=1.21e-10 conditioned to 0.000182
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | RMND1 | 0.17 | 0.12 | lasso | 4 | 0.13 | 2.4e-10 | -5 | 5.3 | 1.2e-07 | -0.74 | 0.79 | 0.21 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RMND1 | 0.09 | 0.02 | lasso | 6 | 0.03 | 2.3e-04 | -5 | 5.2 | 1.8e-07 | -0.74 | 0.54 | 0.26 | FALSE |