Best TWAS P=7.44e-10 · Best GWAS P=4.28e-08 conditioned to 0.0731
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | GIGYF1 | 0.29 | 0.09 | lasso | 3 | 0.12 | 5.6e-05 | 5.4 | 5.4 | 6.5e-08 | 0.93 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Spleen | GIGYF1 | 0.22 | 0.00 | enet | 19 | 0.10 | 1.3e-03 | 5.4 | 6.2 | 7.4e-10 | 0.67 | 0.03 | 0.78 | TRUE |
| 3 | GTEx | Stomach | GIGYF1 | 0.24 | 0.03 | lasso | 5 | 0.07 | 4.7e-04 | 4.5 | 5.8 | 8.4e-09 | 0.61 | 0.09 | 0.70 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GIGYF1 | 0.04 | 0.03 | blup | 29 | 0.03 | 1.7e-04 | 5.4 | 5.2 | 2.2e-07 | 0.89 | 0.00 | 0.96 | FALSE |