Best TWAS P=1.9e-09 · Best GWAS P=4.32e-07 conditioned to 0.896
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | STOX1 | 0.22 | 0.04 | lasso | 11 | 0.06 | 6.4e-03 | 4.2 | 5.4 | 5.4e-08 | 0.77 | 0.04 | 0.62 | FALSE |
| 2 | GTEx | Esophagus Muscularis | STOX1 | 0.15 | 0.07 | lasso | 5 | 0.04 | 3.2e-03 | 4.5 | 5.2 | 2.1e-07 | 0.87 | 0.02 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | STOX1 | 0.18 | 0.08 | blup | 51 | 0.10 | 9.1e-06 | 4.3 | 5.2 | 2.3e-07 | 0.81 | 0.01 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | STOX1 | 0.27 | 0.23 | blup | 51 | 0.23 | 9.1e-08 | 4.5 | 6.0 | 1.9e-09 | 0.83 | 0.02 | 0.91 | TRUE |