Best TWAS P=5.08e-09 · Best GWAS P=1.87e-25 conditioned to 6.89e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | BTG1 | 0.21 | 0.07 | lasso | 3 | 0.03 | 5.3e-02 | 6.2 | 5.8 | 6.9e-09 | 0.51 | 0.07 | 0.06 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CLLU1OS | 0.17 | 0.11 | lasso | 8 | 0.12 | 5.3e-24 | -5.7 | -5.4 | 7.8e-08 | -0.08 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | CLLU1OS | 0.11 | 0.06 | lasso | 4 | 0.04 | 6.9e-03 | -5.7 | -5.4 | 7.5e-08 | -0.08 | 0.01 | 0.69 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | CLLU1OS | 0.16 | 0.06 | lasso | 6 | 0.05 | 8.3e-04 | -5.7 | -5.7 | 1.2e-08 | -0.06 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CLLU1OS | 0.06 | 0.08 | enet | 4 | 0.08 | 1.6e-09 | -5.6 | -5.7 | 1.3e-08 | -0.06 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | CLLU1OS | 0.22 | 0.26 | lasso | 4 | 0.26 | 7.3e-30 | -5.7 | -5.7 | 1.3e-08 | -0.07 | 0.01 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CLLU1OS | 0.13 | 0.14 | lasso | 3 | 0.14 | 2.5e-15 | -5.7 | -5.6 | 2.1e-08 | -0.08 | 0.01 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | CLLU1OS | 0.19 | 0.20 | lasso | 4 | 0.20 | 1.2e-08 | -5.7 | -5.8 | 5.1e-09 | -0.05 | 0.01 | 0.99 | TRUE |
| 9 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CLLU1OS | 0.12 | 0.14 | lasso | 1 | 0.14 | 3.6e-10 | -5.6 | -5.6 | 2.6e-08 | -0.05 | 0.02 | 0.98 | FALSE |