[Hub]/) : Traits : Blood Eosinophil Count :

chr12:89,060,567-90,682,621

Best TWAS P=1.03e-11 · Best GWAS P=1.05e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RP11-981P6.1 0.33 0.29 lasso 3 0.19 2.2e-07 5.7 6.8 1.0e-11 0.08 0.65 0.34 TRUE
2 GTEx Artery Tibial RP11-981P6.1 0.07 0.06 lasso 1 0.03 1.3e-03 5.6 5.6 1.9e-08 0.05 0.41 0.33 FALSE
3 GTEx Colon Sigmoid RP11-981P6.1 0.19 0.12 lasso 4 0.11 9.7e-05 5.7 5.8 7.8e-09 0.05 0.24 0.31 FALSE
4 GTEx Colon Transverse RP11-981P6.1 0.14 0.05 enet 26 0.05 1.9e-03 5.9 6.0 1.4e-09 0.09 0.30 0.28 FALSE
5 GTEx Esophagus Muscularis RP11-981P6.1 0.18 0.10 lasso 3 0.06 2.9e-04 5.8 5.6 2.2e-08 0.06 0.58 0.36 FALSE
6 GTEx Nerve Tibial POC1B 0.30 0.18 lasso 6 0.22 1.0e-15 -5.4 -6.6 3.4e-11 -0.05 0.93 0.07 FALSE
7 GTEx Spleen RP11-981P6.1 0.28 0.18 lasso 13 0.14 2.1e-04 5.6 6.1 1.0e-09 0.06 0.29 0.34 FALSE
8 GTEx Thyroid RP11-981P6.1 0.24 0.25 lasso 5 0.26 3.9e-20 5.8 6.1 1.2e-09 0.05 0.46 0.54 FALSE
9 METSIM Adipose POC1B 0.07 0.03 bslmm 381 0.03 5.2e-05 5.9 -5.8 7.3e-09 -0.06 0.58 0.38 FALSE
10 YFS Blood DUSP6 0.08 0.07 lasso 4 0.07 2.6e-22 6.5 6.6 4.2e-11 0.99 0.00 1.00 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma GALNT4 0.05 0.05 lasso 2 0.04 8.7e-06 -5.3 -5.4 7.4e-08 -0.03 0.10 0.88 FALSE