Best TWAS P=3.25e-10 · Best GWAS P=3.06e-10 conditioned to 0.0389
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | PTPN2 | 0.10 | 0.08 | lasso | 4 | 0.07 | 1.1e-09 | -5.7 | 5.8 | 4.8e-09 | 0.44 | 0.04 | 0.96 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PTPN2 | 0.05 | 0.03 | lasso | 3 | 0.03 | 5.5e-04 | 5.8 | -6.3 | 3.3e-10 | -0.58 | 0.05 | 0.52 | TRUE |