Best TWAS P=9.79e-09 · Best GWAS P=1.02e-08 conditioned to 0.0206
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | ATP5A1 | 0.12 | 0.05 | enet | 34 | 0.02 | 9.1e-03 | -5.7 | 5.7 | 9.8e-09 | -0.72 | 0.01 | 0.98 | TRUE |
2 | METSIM | Adipose | ATP5A1 | 0.03 | 0.04 | lasso | 12 | 0.03 | 4.4e-05 | -5.7 | 5.7 | 1.2e-08 | -0.99 | 0.01 | 0.99 | FALSE |
3 | YFS | Blood | ATP5A1 | 0.14 | 0.16 | lasso | 18 | 0.17 | 2.3e-54 | -5.7 | 5.5 | 3.9e-08 | -0.98 | 0.01 | 0.99 | FALSE |
4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ATP5A1 | 0.02 | 0.02 | lasso | 1 | 0.02 | 1.2e-04 | -5.7 | 5.7 | 1.3e-08 | -1.00 | 0.01 | 0.98 | FALSE |