Best TWAS P=2.56e-09 · Best GWAS P=5.21e-10 conditioned to 0.0647
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ME2 | 0.08 | 0.06 | lasso | 3 | 0.05 | 6.1e-05 | 5.9 | -5.9 | 4.4e-09 | -0.89 | 0.04 | 0.95 | FALSE |
| 2 | GTEx | Spleen | SMAD4 | 0.33 | 0.10 | enet | 1 | 0.08 | 5.6e-03 | 5.9 | 5.9 | 3.1e-09 | 0.92 | 0.04 | 0.64 | FALSE |
| 3 | YFS | Blood | SMAD4 | 0.03 | 0.03 | lasso | 12 | 0.03 | 1.2e-10 | 5.9 | 6.0 | 2.6e-09 | 0.92 | 0.03 | 0.97 | TRUE |