Best TWAS P=1.66e-08 · Best GWAS P=5.05e-08 conditioned to 0.791
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RBCK1 | 0.14 | 0.15 | lasso | 4 | 0.15 | 2.9e-21 | -5.4 | -5.3 | 8.8e-08 | 0.99 | 0 | 1.00 | FALSE |
| 2 | METSIM | Adipose | SIRPB1 | 0.21 | 0.18 | lasso | 9 | 0.18 | 1.2e-25 | 5.1 | 5.2 | 1.7e-07 | -0.08 | 0 | 0.99 | FALSE |
| 3 | YFS | Blood | RBCK1 | 0.26 | 0.21 | bslmm | 485 | 0.23 | 6.6e-74 | -5.4 | -5.6 | 1.7e-08 | 0.90 | 0 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SIRPB1 | 0.11 | 0.02 | lasso | 3 | 0.02 | 1.4e-02 | 5.1 | 5.3 | 1.2e-07 | -0.09 | 0 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SIRPB1 | 0.21 | 0.07 | lasso | 3 | 0.07 | 6.8e-14 | 5.4 | 5.4 | 5.9e-08 | -0.09 | 0 | 1.00 | TRUE |