[Hub]/) : Traits : Blood Eosinophil Count :

chr19:51,479,402-53,017,693

Best TWAS P=1.01e-14 · Best GWAS P=7e-17 conditioned to 2.84e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 NTR Blood FPR2 0.10 0.08 bslmm 611 0.08 5.6e-24 6.11 -6.3 2.7e-10 0.03 1.00 0.00 FALSE
2 YFS Blood FPR2 0.56 0.40 lasso 10 0.50 1.2e-192 6.11 -6.7 1.8e-11 0.07 1.00 0.00 FALSE
3 YFS Blood FPR3 0.15 0.05 bslmm 596 0.10 2.2e-32 -0.27 -6.2 7.2e-10 0.04 1.00 0.00 FALSE
4 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CD33 0.10 0.01 enet 18 0.06 2.0e-04 4.93 5.3 1.1e-07 0.02 0.08 0.24 TRUE
5 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SIGLEC5 0.14 0.00 blup 73 0.03 7.2e-03 -5.85 -5.7 1.2e-08 0.44 0.02 0.49 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma SIGLEC5 0.12 0.00 lasso 4 0.02 3.5e-03 2.93 -5.2 2.4e-07 0.41 0.03 0.67 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma FPR3 0.05 0.01 lasso 4 0.02 2.7e-03 6.16 -7.7 1.6e-14 -0.02 0.08 0.13 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FPR3 0.05 0.03 blup 97 0.02 1.0e-03 -4.88 -7.4 1.4e-13 0.11 0.03 0.18 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SIGLEC5 0.06 0.01 blup 73 0.03 3.8e-04 -5.85 -6.5 9.7e-11 0.35 0.03 0.73 TRUE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma FPR3 0.17 0.10 lasso 2 0.07 9.7e-04 -4.88 -5.3 1.2e-07 0.10 0.07 0.06 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma SIGLEC14 0.17 0.05 lasso 4 0.10 6.3e-11 -6.26 -6.1 1.3e-09 0.41 0.59 0.40 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma SIGLEC5 0.15 0.05 blup 73 0.08 3.9e-09 3.41 -6.0 1.6e-09 0.40 0.12 0.86 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma FPR3 0.07 0.00 blup 97 0.00 1.9e-01 -4.88 -7.7 1.0e-14 0.06 0.02 0.11 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma SIGLEC14 0.17 0.04 enet 16 0.08 4.6e-08 2.93 -6.3 2.8e-10 0.32 0.62 0.27 TRUE