Best TWAS P=4.25e-09 · Best GWAS P=1.99e-09 conditioned to 3.28e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | LCLAT1 | 0.30 | 0.08 | enet | 34 | 0.08 | 2.6e-05 | -5.8 | -5.5 | 4.5e-08 | -0.07 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Liver | LCLAT1 | 0.34 | 0.24 | lasso | 4 | 0.18 | 7.2e-06 | -5.8 | -5.8 | 4.8e-09 | -0.07 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Pancreas | LCLAT1 | 0.23 | 0.09 | lasso | 6 | 0.07 | 7.0e-04 | -5.7 | -5.3 | 1.4e-07 | -0.09 | 0.04 | 0.94 | FALSE |
| 4 | GTEx | Spleen | LCLAT1 | 0.53 | 0.15 | lasso | 7 | 0.09 | 2.2e-03 | -5.5 | -5.3 | 9.4e-08 | -0.06 | 0.04 | 0.79 | FALSE |
| 5 | GTEx | Stomach | LCLAT1 | 0.26 | 0.10 | lasso | 5 | 0.08 | 7.7e-05 | -5.8 | -5.9 | 4.3e-09 | -0.08 | 0.02 | 0.97 | TRUE |
| 6 | NTR | Blood | LCLAT1 | 0.15 | 0.25 | enet | 24 | 0.25 | 6.5e-81 | -5.8 | -5.6 | 2.0e-08 | -0.10 | 0.01 | 0.99 | FALSE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | LCLAT1 | 0.06 | 0.03 | lasso | 4 | 0.02 | 5.7e-04 | -5.7 | -5.6 | 1.8e-08 | -0.07 | 0.02 | 0.98 | FALSE |
| 8 | YFS | Blood | LCLAT1 | 0.38 | 0.63 | bslmm | 593 | 0.63 | 7.7e-276 | -5.8 | -5.7 | 1.0e-08 | -0.08 | 0.01 | 0.99 | FALSE |