Best TWAS P=4.47e-09 · Best GWAS P=2.62e-33 conditioned to 2.34e-32
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | AC074117.10 | 0.06 | 0.01 | lasso | 2 | 0.04 | 2.7e-02 | 5.4 | 5.9 | 4.5e-09 | 0.03 | 0.02 | 0.58 | TRUE |
| 2 | GTEx | Stomach | AC074117.10 | 0.06 | 0.01 | lasso | 7 | 0.01 | 7.8e-02 | -2.5 | 5.8 | 7.7e-09 | 0.01 | 0.05 | 0.74 | FALSE |
| 3 | YFS | Blood | MRPL33 | 0.02 | 0.01 | blup | 385 | 0.01 | 6.4e-05 | 4.5 | -5.2 | 1.9e-07 | -0.03 | 0.97 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | FNDC4 | 0.24 | 0.09 | enet | 9 | 0.17 | 1.9e-16 | 5.9 | 5.3 | 1.3e-07 | 0.01 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | GCKR | 0.18 | 0.08 | enet | 5 | 0.13 | 1.7e-12 | 5.8 | 5.2 | 1.6e-07 | 0.02 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | IFT172 | 0.08 | 0.01 | blup | 43 | 0.02 | 6.1e-03 | 5.2 | 5.3 | 1.2e-07 | 0.05 | 0.00 | 0.83 | FALSE |