Best TWAS P=1.5e-11 · Best GWAS P=5.46e-11 conditioned to 8.71e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | AC010883.5 | 0.16 | 0.07 | lasso | 6 | 0.07 | 2.4e-04 | 3.4 | -5.8 | 8.7e-09 | 0.11 | 0.21 | 0.39 | TRUE |
| 2 | GTEx | Thyroid | AC010883.5 | 0.11 | 0.09 | lasso | 2 | 0.08 | 1.5e-06 | -5.1 | -5.2 | 2.5e-07 | 0.01 | 0.81 | 0.16 | FALSE |
| 3 | GTEx | Vagina | ZFP36L2 | 0.32 | 0.08 | enet | 27 | 0.14 | 4.7e-04 | -2.3 | 5.5 | 4.8e-08 | -0.13 | 0.08 | 0.11 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP36L2 | 0.03 | 0.01 | blup | 38 | 0.01 | 1.1e-02 | -5.1 | 6.8 | 1.5e-11 | 0.06 | 0.01 | 0.71 | TRUE |