Best TWAS P=4.87e-09 · Best GWAS P=1.06e-06 conditioned to 0.536
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | C1orf134 | 0.07 | 0.00 | lasso | 4 | 0.02 | 0.018 | 4.6 | 5.2 | 1.7e-07 | 0.74 | 0.04 | 0.70 | FALSE |
2 | GTEx | Whole Blood | ARHGEF19-AS1 | 0.05 | 0.01 | lasso | 6 | 0.01 | 0.100 | 4.7 | -5.8 | 4.9e-09 | -0.77 | 0.03 | 0.78 | TRUE |