[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr1:11,032,827-12,786,444

Best TWAS P=1.41e-35 · Best GWAS P=3.1e-34 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MIIP	0.08	0.08	lasso	3	0.07	5.6e-09	11.6	-11.5	2.2e-30	-0.82	0.20	0.80	FALSE
2	GTEx	Adipose Subcutaneous	MFN2	0.18	0.12	lasso	5	0.12	4.6e-10	6.6	7.0	2.6e-12	0.46	1.00	0.00	TRUE
3	GTEx	Adipose Visceral Omentum	MFN2	0.22	0.08	enet	4	0.10	7.5e-06	6.9	7.1	1.6e-12	0.50	0.92	0.01	FALSE
4	GTEx	Cells Transformed fibroblasts	MFN2	0.17	0.17	lasso	5	0.19	4.4e-14	6.9	8.0	9.9e-16	0.55	1.00	0.00	FALSE
5	GTEx	Lung	MFN2	0.18	0.11	lasso	6	0.12	9.6e-10	8.4	8.9	5.3e-19	0.54	1.00	0.00	FALSE
6	GTEx	Skin Sun Exposed Lower leg	MFN2	0.10	0.02	lasso	3	0.01	5.1e-02	9.2	9.3	1.0e-20	0.43	0.63	0.02	FALSE
7	GTEx	Spleen	MFN2	0.36	0.18	enet	12	0.18	2.6e-05	9.4	8.3	8.1e-17	0.49	0.79	0.04	FALSE
8	GTEx	Vagina	FBXO6	0.45	0.14	lasso	8	0.10	3.2e-03	8.3	-7.2	4.4e-13	-0.42	0.08	0.12	TRUE
9	GTEx	Whole Blood	PLOD1	0.19	0.16	lasso	5	0.22	6.9e-20	8.3	8.1	5.2e-16	0.51	1.00	0.00	FALSE
10	GTEx	Whole Blood	KIAA2013	0.17	0.14	enet	19	0.16	1.6e-14	8.3	8.3	9.8e-17	0.46	1.00	0.00	FALSE
11	GTEx	Whole Blood	MFN2	0.40	0.48	lasso	3	0.53	1.6e-56	8.3	8.2	1.6e-16	0.50	1.00	0.00	FALSE
12	GTEx	Whole Blood	MIIP	0.22	0.19	lasso	3	0.19	2.5e-17	8.4	8.3	6.8e-17	0.47	1.00	0.00	FALSE
13	METSIM	Adipose	MFN2	0.06	0.07	lasso	3	0.06	1.0e-08	6.9	7.8	8.4e-15	0.60	0.97	0.03	TRUE
14	NTR	Blood	MFN2	0.14	0.16	lasso	3	0.17	5.1e-52	6.9	7.6	3.1e-14	0.54	1.00	0.00	FALSE
15	NTR	Blood	PLOD1	0.03	0.03	lasso	3	0.02	1.8e-08	7.6	7.5	5.6e-14	0.50	1.00	0.00	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	MIIP	0.10	0.07	enet	14	0.09	1.2e-11	11.6	-11.0	3.5e-28	-0.71	0.36	0.64	TRUE
17	YFS	Blood	KIAA2013	0.11	0.12	lasso	5	0.12	4.8e-37	6.6	7.9	2.7e-15	0.41	1.00	0.00	FALSE
18	YFS	Blood	MFN2	0.45	0.58	lasso	7	0.65	2.1e-290	6.9	8.2	3.4e-16	0.52	1.00	0.00	FALSE
19	YFS	Blood	PLOD1	0.25	0.30	enet	31	0.36	8.7e-124	8.4	6.4	1.6e-10	0.46	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MIIP	0.07	0.01	enet	9	0.02	1.8e-02	9.4	-9.8	8.6e-23	-0.51	0.02	0.14	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	MIIP	0.03	0.03	lasso	4	0.02	1.1e-05	11.6	-12.2	2.1e-34	-0.79	0.26	0.73	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	MFN2	0.09	0.06	enet	8	0.07	4.2e-05	6.9	9.8	1.8e-22	0.66	0.46	0.28	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	MIIP	0.05	0.04	enet	3	0.04	2.8e-03	9.9	-8.8	1.2e-18	-0.45	0.07	0.18	FALSE
24	The Cancer Genome Atlas	Glioblastoma Multiforme	MIIP	0.15	0.11	lasso	2	0.08	2.0e-03	11.6	-11.8	2.9e-32	-0.81	0.01	0.95	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MFN2	0.02	0.02	blup	57	0.02	4.0e-03	9.4	7.2	8.5e-13	0.39	0.12	0.03	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	MIIP	0.07	0.07	enet	5	0.07	3.6e-08	11.6	-12.4	1.4e-35	-0.78	0.36	0.64	TRUE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PLOD1	0.15	0.13	enet	9	0.06	1.9e-03	4.3	-5.5	3.2e-08	-0.24	0.43	0.06	TRUE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	MIIP	0.09	0.08	enet	4	0.08	4.2e-09	11.6	-12.3	7.6e-35	-0.92	0.01	0.99	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	MFN2	0.18	0.01	blup	57	0.04	4.2e-05	-6.3	7.1	1.1e-12	0.20	0.01	0.04	TRUE