Best TWAS P=1.56e-09 · Best GWAS P=2.42e-11 conditioned to 1.1e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | STK17B | 0.17 | 0.00 | lasso | 6 | 0.01 | 2.1e-02 | -0.83 | -5.2 | 2.2e-07 | 0.46 | 0.10 | 0.47 | FALSE |
| 2 | YFS | Blood | STK17B | 0.08 | 0.05 | blup | 376 | 0.05 | 8.7e-17 | -6.29 | -5.8 | 5.2e-09 | 0.49 | 0.09 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DNAH7 | 0.04 | 0.01 | blup | 102 | 0.02 | 1.4e-05 | -4.11 | 6.0 | 1.6e-09 | -0.46 | 0.31 | 0.68 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | DNAH7 | 0.15 | 0.17 | lasso | 6 | 0.14 | 5.2e-14 | -5.03 | 5.2 | 1.8e-07 | -0.50 | 0.26 | 0.73 | FALSE |