Best TWAS P=8.89e-11 · Best GWAS P=3.23e-13 conditioned to 0.000688
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | XRN1 | 0.09 | 0.02 | enet | 9 | 0.03 | 0.00703 | -6.8 | -5.8 | 6.8e-09 | 0.87 | 0.03 | 0.92 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | TRPC1 | 0.09 | 0.04 | lasso | 2 | 0.04 | 0.00048 | -5.9 | 6.5 | 8.9e-11 | -0.84 | 0.12 | 0.77 | TRUE |