Best TWAS P=1.89e-10 · Best GWAS P=1.49e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PEF1 | 0.04 | 0.04 | lasso | 4 | 0.03 | 2.8e-04 | -6.0 | 6.2 | 7.0e-10 | -0.98 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Artery Tibial | PEF1 | 0.10 | 0.09 | enet | 16 | 0.09 | 9.0e-08 | -6.1 | 5.2 | 1.6e-07 | -0.87 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Colon Sigmoid | PEF1 | 0.16 | 0.09 | lasso | 3 | 0.09 | 4.3e-04 | -5.9 | 5.5 | 3.0e-08 | -0.90 | 0.04 | 0.84 | FALSE |
| 4 | METSIM | Adipose | PEF1 | 0.03 | 0.02 | enet | 17 | 0.02 | 7.9e-04 | -6.3 | 6.1 | 8.7e-10 | -0.79 | 0.01 | 0.97 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | PEF1 | 0.04 | 0.04 | lasso | 3 | 0.02 | 4.2e-04 | -6.3 | 6.4 | 1.9e-10 | -0.97 | 0.01 | 0.99 | TRUE |