[Hub]/) : Traits : Lung FVC : ← →

chr4:17,104,059-18,507,692

Best TWAS P=8.89e-15 · Best GWAS P=2.25e-10 conditioned to 0.187

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	DCAF16	0.21	0.15	lasso	3	0.17	5.1e-14	5.6	5.5	3.2e-08	-0.21	0.37	0.63	FALSE
2	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	5.6	6.0	1.9e-09	-0.32	0.28	0.48	FALSE
3	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-5.9	7.0	1.8e-12	-0.69	0.09	0.64	FALSE
4	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	5.2	6.0	2.5e-09	-0.31	0.34	0.66	FALSE
5	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	5.7	6.9	5.9e-12	-0.45	0.12	0.72	FALSE
6	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-5.7	7.8	8.9e-15	-0.70	0.04	0.61	TRUE
7	GTEx	Breast Mammary Tissue (Female)	DCAF16	0.16	0.13	lasso	2	0.06	7.8e-03	5.6	5.5	4.2e-08	-0.24	0.06	0.17	FALSE
8	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	5.7	5.7	1.0e-08	-0.32	0.10	0.52	FALSE
9	GTEx	Esophagus Muscularis	DCAF16	0.16	0.14	lasso	3	0.14	9.3e-09	5.6	5.6	2.5e-08	-0.23	0.33	0.66	FALSE
10	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	5.6	6.2	4.2e-10	-0.32	0.36	0.64	FALSE
11	GTEx	Skin Sun Exposed Lower leg	DCAF16	0.14	0.12	enet	14	0.12	5.4e-10	5.7	5.8	5.7e-09	-0.25	0.31	0.69	FALSE
12	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	5.6	7.1	9.5e-13	-0.66	0.05	0.58	FALSE
13	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	5.3	6.2	8.0e-10	-0.23	0.08	0.57	FALSE
14	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	5.6	6.9	4.7e-12	-0.53	0.10	0.81	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-5.8	5.7	1.6e-08	-0.79	0.04	0.86	FALSE
16	YFS	Blood	DCAF16	0.02	0.02	lasso	1	0.01	1.1e-04	5.2	5.2	1.6e-07	-0.22	0.28	0.68	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-5.8	-5.6	2.3e-08	0.72	0.10	0.90	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	5.2	6.9	4.3e-12	-0.55	0.15	0.62	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-5.8	-5.8	5.2e-09	0.76	0.02	0.70	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	5.6	7.2	6.3e-13	-0.60	0.14	0.61	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-6.2	-5.4	6.7e-08	0.86	0.01	0.80	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	5.3	6.6	3.5e-11	-0.55	0.24	0.64	FALSE