Hub : Traits :

Lung FVC

4807 significantly associated models · 1026 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 838555 2573199 5 2 3.8e-11 4.8e-17 1.5e-14 16 CALML6 RP1-283E3.4
2 1 7314655 8738937 2 1 7.8e-10 1.4e-09 1.0e+00 100 PARK7
3 1 15752716 18132937 18 2 8.6e-24 2.2e-22 2.6e-02 95 ANO7P1 MST1P2
4 1 22197336 22718991 1 1 1.6e-12 7.2e-13 1.2e-11 11 WNT4
5 1 24634151 25180321 1 1 1.8e-08 1.7e-06 4.0e-01 97 C1orf130
6 1 25752617 27595862 5 2 1.2e-09 2.8e-08 2.1e-01 95 PDIK1L RPS6KA1
7 1 40799427 42542658 2 1 1.2e-08 8.4e-07 6.3e-03 69 SCMH1
8 1 65638930 66341764 1 1 7.5e-09 4.8e-14 1.8e-08 44 LEPR
9 1 77547831 79041520 2 1 2.1e-09 2.6e-09 3.1e-01 97 USP33
10 1 87083322 87821546 2 1 1.9e-07 4.3e-07 1.2e-01 90 HS2ST1
11 1 112312154 113941737 7 1 1.9e-10 9.7e-09 2.0e-03 71 ST7L
12 1 114893146 116330558 1 1 1.2e-08 1.4e-09 6.2e-03 80 TSPAN2
13 1 149672809 151836824 27 5 1.2e-31 3.6e-28 NaN NaN CERS2 CTSS MRPS21 PPIAL4C
14 1 153241677 155910830 8 2 2.4e-13 1.9e-13 1.1e-01 95 MUC1 RP11-422P24.10
15 1 178129899 179534540 1 1 9.3e-08 7.2e-10 1.8e-03 74 ANGPTL1
16 1 182744205 184266571 1 1 1.4e-08 3.7e-07 5.1e-01 98 SMG7
17 1 195927451 197488569 4 1 3.9e-11 2.4e-11 1.0e+00 100 CFHR3
18 1 203692179 206329620 6 4 1.0e-15 5.0e-14 2.9e-03 84 DSTYK LRRN2 MDM4 RAB7L1
19 1 206802184 208231688 1 1 1.1e-09 4.1e-09 2.0e-01 95 CD55
20 1 209867116 210585575 1 1 3.1e-08 1.7e-11 6.6e-05 65 SYT14
21 1 217760821 219208920 1 1 3.3e-14 4.5e-19 2.0e-17 9 RRP15
22 1 220171786 221753645 5 2 6.4e-20 8.9e-30 6.7e-18 42 C1orf115 HLX
23 1 223846564 225265424 1 1 4.0e-09 5.7e-09 1.0e+00 100 CNIH4
24 2 23453834 25083310 2 1 2.2e-14 7.6e-14 1.5e-01 96 UBXN2A
25 2 32483593 34319972 1 1 7.2e-09 3.2e-12 2.7e-05 64 LTBP1
26 2 42030533 42531871 1 1 1.8e-07 4.8e-10 6.5e-04 70 PKDCC
27 2 47224927 49519654 8 10 2.1e-17 1.9e-14 NaN NaN FOXN2 KLRAQ1 MSH6 STON1
28 2 54817683 56843605 2 2 1.4e-36 6.3e-36 2.2e-03 94 EFEMP1
29 2 60677772 62069528 1 1 1.9e-08 3.7e-08 1.6e-01 93 AC016747.3
30 2 68850921 71228388 6 2 8.4e-16 6.2e-18 2.3e-06 70 C2orf42 GFPT1
31 2 88239332 89130009 3 1 1.6e-13 2.3e-13 1.0e+00 100 AC062029.1
32 2 100193898 101629737 1 1 1.8e-08 3.1e-09 3.8e-02 88 LONRF2
33 2 134513621 137435625 9 6 4.3e-17 8.7e-16 NaN NaN AC016725.4 DARS LCT MCM6
34 2 156594333 158165818 1 1 2.0e-07 8.7e-10 4.5e-05 56 GPD2
35 2 177451264 180139951 8 2 7.4e-21 1.9e-20 8.3e-01 100 AC073834.3 RP11-171I2.2
36 2 190583187 192091293 2 1 1.0e-10 6.2e-09 8.9e-02 92 TMEM194B
37 2 202434393 204549680 2 2 8.7e-10 3.2e-10 6.5e-03 81 CARF NOP58
38 2 209599808 211264173 1 1 5.0e-20 4.3e-20 1.0e+00 100 MAP2
39 2 217908472 219846749 2 2 6.4e-08 3.8e-19 1.9e-16 15 DIRC3 TMBIM1
40 2 224636490 226142508 1 1 1.4e-15 9.1e-09 7.9e-01 100 CUL3
41 2 226980411 228725864 3 1 2.2e-08 9.8e-09 1.0e+00 100 RHBDD1
42 2 231564626 234145080 5 4 2.8e-08 6.0e-08 8.8e-03 77 B3GNT7 CHRNG COPS7B DIS3L2
43 2 238531976 239996179 1 1 2.5e-08 3.0e-12 1.8e-05 62 TRAF3IP1
44 2 241332207 243048760 5 2 1.7e-23 3.5e-22 4.1e-01 99 BOK C2orf54
45 3 8123440 9674325 2 2 2.5e-08 3.5e-09 5.0e-02 89 LMCD1 RAD18
46 3 11829474 13274240 1 1 1.6e-07 2.9e-10 1.1e-06 40 TSEN2
47 3 32339493 33950934 2 2 5.6e-11 8.8e-23 3.1e-19 17 GLB1 SUSD5
48 3 48702606 51398958 17 3 6.9e-13 2.6e-09 4.9e-05 54 RNF123 SEMA3B-AS1
49 3 56629678 58613378 2 1 3.6e-10 4.7e-11 1.0e+00 100 SLMAP
50 3 70757099 71880670 1 1 1.2e-17 1.1e-20 1.1e-07 68 FOXP1
51 4 1398897 1917862 1 1 1.6e-09 2.5e-08 2.0e-01 95 FAM53A
52 4 2233366 4219590 5 3 1.1e-14 3.8e-13 1.0e+00 100 GRK4 LRPAP1
53 4 4774402 5270485 1 1 3.7e-08 3.0e-09 4.0e-03 76 CYTL1
54 4 8335737 8731330 1 1 1.1e-07 2.2e-08 1.0e+00 100 CPZ
55 4 17104059 18507692 2 1 8.9e-15 2.2e-10 1.9e-01 96 DCAF16
56 4 40576393 41465695 1 1 5.9e-08 2.7e-05 4.5e-03 54 APBB2
57 4 53557678 55018996 1 1 1.1e-07 6.4e-08 1.0e+00 100 FIP1L1
58 4 55698811 56238263 1 1 1.6e-09 7.1e-11 2.0e-07 36 KDR
59 4 57080198 58674284 4 2 3.4e-09 1.3e-08 1.0e+00 100 IGFBP7 NOA1
60 4 76660500 78402379 1 1 1.0e-09 2.2e-09 1.3e-01 94 SHROOM3
61 4 87165758 88859131 2 1 3.1e-10 2.3e-11 2.3e-02 88 AFF1
62 4 89335667 90734728 1 1 3.3e-11 5.6e-19 4.1e-11 45 TIGD2
63 4 99528449 100942337 1 1 1.9e-08 8.9e-10 2.7e-05 53 ADH1B
64 4 105373669 107622327 5 1 1.9e-39 1.7e-39 1.0e+00 100 INTS12
65 4 127856015 129581793 2 1 2.7e-09 2.9e-11 2.4e-03 79 INTU
66 4 145203531 146706624 1 1 4.4e-08 1.1e-28 1.6e-31 -10 ANAPC10
67 4 150316563 151871473 1 1 5.6e-08 2.1e-10 2.6e-04 67 DCLK2
68 4 165595556 167114948 1 1 9.5e-12 6.8e-12 1.0e+00 100 CPE
69 4 169317081 170886793 1 1 3.7e-08 8.3e-08 7.2e-02 89 SH3RF1
70 5 42321011 44403631 6 3 5.7e-14 1.6e-20 5.2e-14 34 CTD-2201E18.3 NNT PAIP1
71 5 51592336 53083975 1 1 7.1e-10 7.5e-14 8.8e-06 65 ITGA2
72 5 60983430 62394367 1 1 3.2e-08 7.4e-13 2.1e-06 56 DIMT1
73 5 67818581 68828296 1 1 4.8e-08 4.3e-09 3.6e-04 63 MRPS36
74 5 77052232 79318982 5 2 1.2e-10 6.9e-15 3.1e-06 64 AP3B1 JMY
75 5 92051598 93624507 2 1 6.4e-11 1.1e-10 1.4e-01 95 NR2F1
76 5 117907292 119434193 1 1 6.5e-08 1.7e-09 6.7e-03 80 TNFAIP8
77 5 121153924 123058338 5 2 5.7e-12 2.1e-13 6.6e-04 78 CEP120 CTB-36H16.2
78 5 126587995 128220643 4 4 1.2e-13 1.2e-11 1.0e+00 100 CTC-228N24.3 SLC12A2
79 5 129797129 133140038 16 3 4.9e-21 4.2e-17 3.0e-01 98 HSPA4 LEAP2 P4HA2
80 5 138933151 140784895 7 1 1.9e-09 3.0e-07 2.1e-01 94 ZMAT2
81 5 141958831 143510824 1 1 5.4e-08 1.7e-13 4.5e-07 53 NR3C1
82 5 147063674 150635429 6 3 1.2e-17 1.7e-15 7.2e-01 100 ABLIM3 HTR4 NDST1
83 6 925581 2945331 1 1 9.5e-09 2.7e-12 7.0e-13 -5 GMDS
84 6 6701209 8278455 3 3 2.6e-15 2.5e-39 3.6e-38 3 BMP6 DSP RIOK1
85 6 33856903 36581149 11 3 1.8e-09 2.9e-10 1.0e-09 6 C6orf106 FKBP5 PPARD
86 6 44079216 46083971 2 2 9.7e-09 2.1e-11 1.2e-04 67 RP1-244F24.1 SUPT3H
87 6 55222696 56954550 1 1 1.0e-09 1.5e-12 1.4e-06 53 COL21A1
88 6 73090786 74157617 1 1 2.0e-07 2.1e-06 4.8e-04 46 KCNQ5
89 6 75612601 77324522 2 2 7.8e-11 6.2e-11 4.9e-04 72 SENP6
90 6 80120201 81763771 2 1 1.8e-11 3.0e-10 4.1e-01 98 RP11-250B2.6
91 6 99324687 100719911 1 1 5.6e-08 1.4e-06 9.0e-01 100 RP1-199J3.5
92 6 104478130 106230491 2 1 3.2e-16 9.3e-17 1.0e+00 100 LIN28B
93 6 108183628 110461195 3 2 1.1e-07 6.3e-08 1.1e-01 92 FOXO3 SMPD2
94 6 125970401 127355237 1 1 2.6e-18 5.0e-19 3.9e-05 79 CENPW
95 6 130464889 132080991 2 1 1.5e-10 6.9e-11 1.4e-01 95 EPB41L2
96 6 133575570 136516257 6 4 1.5e-13 1.8e-14 9.9e-02 95 C6orf217 SLC2A12 TBPL1 TCF21
97 6 143565218 145078694 1 1 3.4e-09 6.2e-11 4.5e-10 9 PLAGL1
98 6 154487421 156330580 4 1 2.0e-11 5.2e-11 3.7e-02 90 RP11-477D19.2
99 6 157713662 159884002 3 3 9.8e-13 1.2e-13 7.6e-01 100 MIR3918 TULP4
100 6 168923561 170799392 4 2 9.2e-17 1.6e-17 2.1e-03 87 RP1-137D17.1 THBS2
101 7 1161158 2972072 1 1 1.6e-08 3.1e-08 7.8e-03 77 MAD1L1
102 7 5925156 7988091 3 2 9.4e-09 4.3e-08 6.0e-05 46 AC079742.4 C1GALT1
103 7 17133294 19854141 2 3 4.0e-11 9.8e-16 2.0e-10 37 SNX13 TWIST1
104 7 22946782 24382726 1 1 1.8e-08 1.4e-16 3.6e-15 9 CCDC126
105 7 25715984 28468319 5 4 9.1e-20 6.9e-23 2.1e-03 90 AC004540.4 JAZF1 KIAA0087 SKAP2
106 7 64498257 66931015 3 1 3.7e-09 3.9e-07 1.2e-01 91 VKORC1L1
107 7 104060000 105606983 2 1 8.4e-10 1.5e-08 2.6e-01 96 LOC723809
108 7 139700516 141413051 5 6 2.3e-15 2.0e-15 1.0e+00 100 BRAF MRPS33 NDUFB2 NDUFB2-AS1
109 7 149847287 151474607 7 2 2.1e-09 2.1e-08 8.3e-01 100 AOC1 TMUB1
110 8 21416204 23240950 9 2 4.2e-11 4.3e-11 1.0e+00 100 BIN3 POLR3D
111 8 32670264 34065815 1 1 1.2e-09 1.8e-08 5.9e-05 49 TTI2
112 8 37329315 39836128 4 2 1.3e-08 6.0e-07 2.2e-02 79 ADAM32 RP11-90P5.2
113 8 48221724 49584958 1 1 1.3e-10 4.1e-12 2.3e-05 63 MCM4
114 8 56094665 57683880 2 1 1.5e-13 6.9e-14 6.2e-02 94 RPS20
115 8 60903659 62477554 1 1 5.3e-08 5.7e-10 1.0e+00 100 CHD7
116 8 85591518 87083747 3 1 2.5e-12 5.3e-13 5.5e-02 93 RP11-317J10.2
117 9 14857740 16758776 1 1 1.4e-12 8.4e-12 6.5e-02 93 CCDC171
118 9 85657836 87315117 4 1 5.4e-13 4.4e-12 1.9e-01 96 RMI1
119 9 94363366 96126104 6 1 8.7e-12 1.0e-10 1.0e-02 84 NOL8
120 9 97520168 98975128 2 1 2.6e-28 1.1e-32 4.5e-06 85 PTCH1
121 9 135629944 137034272 2 1 1.1e-10 7.7e-09 1.8e-04 58 ABO
122 9 138403706 140031290 8 2 1.5e-26 1.9e-26 1.0e+00 100 QSOX2 SDCCAG3
123 10 11167624 13569805 4 3 3.7e-13 2.4e-15 1.0e-01 96 CAMK1D CDC123 PROSER2
124 10 21087485 22724472 2 1 1.5e-09 7.9e-11 1.6e-02 86 MLLT10
125 10 30411253 32016090 1 1 2.1e-10 7.7e-09 5.6e-01 99 ZNF438
126 10 52507396 54301740 1 1 2.8e-11 3.3e-13 2.7e-04 75 PRKG1
127 10 63414038 64105321 1 1 6.8e-10 4.5e-13 1.8e-05 65 ARID5B
128 10 64195778 65606229 2 1 5.8e-11 6.7e-11 6.9e-02 92 JMJD1C
129 10 69293282 71273696 7 3 3.4e-16 6.8e-31 6.6e-07 82 ATOH7 HKDC1 PBLD
130 10 74714177 76373904 12 1 1.0e-17 6.5e-18 1.0e+00 100 CHCHD1
131 10 76664253 79018276 1 1 3.4e-19 1.6e-25 3.1e-08 72 C10orf11
132 10 80443273 81901722 1 1 2.2e-11 3.2e-20 1.4e-13 36 ZCCHC24
133 10 95060188 96779866 1 1 4.6e-09 5.2e-10 1.0e+00 100 PLCE1
134 10 104939215 106371784 2 1 3.7e-10 1.1e-09 1.0e+00 100 RP11-541N10.3
135 10 117949460 119582073 1 1 9.1e-08 1.1e-07 3.3e-01 97 KIAA1598
136 10 123965678 124462596 1 1 5.5e-13 1.9e-27 1.6e-16 42 ARMS2
137 11 32812529 33376095 1 1 7.2e-09 1.4e-06 9.7e-02 88 TCP11L1
138 11 42881882 45937306 3 2 1.2e-17 7.2e-17 1.0e+00 100 PRDM11 RP11-613D13.5
139 11 60965461 63284510 14 3 2.7e-30 9.5e-29 5.0e-02 97 EEF1G RAB3IL1 RPLP0P2
140 11 64789077 69406625 31 15 3.2e-15 4.0e-16 NaN NaN AIP B3GNT1 BANF1 C11orf80 CCDC87 CTSF DPP3 EIF1AD GSTP1 MRPL21 RIN1 RP11-755F10.1 SF3B2 SLC29A2
141 11 71769936 73198494 1 1 3.8e-08 3.7e-07 3.5e-01 97 STARD10
142 11 88358544 89943681 1 1 1.1e-07 7.7e-09 6.2e-03 78 NOX4
143 11 116352008 117770775 2 1 1.8e-08 1.7e-08 3.6e-02 86 SIDT2
144 11 118365263 119765318 1 1 1.4e-07 4.6e-06 2.0e-02 74 CCDC153
145 11 127866485 129376495 1 1 1.1e-09 1.8e-12 3.5e-12 3 FLI1
146 11 129575976 130992111 1 1 7.5e-11 1.0e-11 3.2e-03 81 ADAMTS8
147 12 403545 2299048 1 1 8.0e-10 1.4e-16 1.7e-08 53 ERC1
148 12 2489314 4086893 1 1 8.6e-08 3.4e-12 1.4e-14 -22 TSPAN9
149 12 26986748 29432481 5 9 1.5e-71 3.7e-66 1.0e+00 100 CCDC91 MRPS35 RP11-860B13.1 RP11-967K21.1
150 12 30084002 31526510 1 1 3.0e-12 3.7e-14 1.9e-03 83 IPO8
151 12 48039874 49444545 1 1 1.8e-07 5.0e-08 2.6e-03 70 ZNF641
152 12 49556303 51912062 6 2 4.3e-12 1.6e-11 1.0e+00 100 BCDIN3D DIP2B
153 12 54131094 54760824 5 3 2.1e-13 5.1e-23 2.4e-05 82 FLJ12825 HOXC10 HOXC6
154 12 55694116 57545756 3 2 2.6e-08 2.4e-07 9.2e-02 89 SPRYD4 SUOX
155 12 64519806 65969015 1 1 1.2e-09 2.3e-15 5.7e-12 24 TBC1D30
156 13 49123516 50962458 5 3 1.2e-10 3.7e-09 1.0e+00 100 CAB39L CDADC1 EBPL
157 13 72585542 74288499 2 1 6.4e-08 4.4e-07 8.3e-07 5 PIBF1
158 13 100558473 102022883 1 1 2.0e-08 5.7e-07 6.4e-01 99 TMTC4
159 14 36900126 38265117 2 1 5.4e-10 1.8e-12 2.3e-04 73 SLC25A21
160 14 53731553 55957996 2 2 2.0e-08 2.1e-09 3.6e-05 52 BMP4 SAMD4A
161 14 58981102 60650086 3 1 5.3e-08 3.8e-08 4.1e-03 73 DAAM1
162 14 60754455 62242523 1 1 6.8e-08 7.2e-10 1.0e+00 100 SLC38A6
163 14 69599570 70172278 2 1 4.8e-08 5.5e-07 1.6e-01 92 ERH
164 14 73672831 76593690 6 4 1.8e-10 1.7e-26 6.7e-17 38 ALDH6A1 ISCA2 RP11-293M10.6 RP5-1021I20.4
165 14 85758554 86335746 1 1 3.6e-10 3.6e-08 2.0e-02 82 FLRT2
166 14 91738696 94495324 7 4 4.8e-31 1.3e-30 1.0e+00 100 BTBD7 RIN3 RP11-529H20.5
167 15 39530508 42886656 17 14 5.7e-15 1.8e-15 NaN NaN BMF CHP DISP2 EIF2AK4 FSIP1 GCHFR PAK6 RP11-23P13.7 RP11-64K12.8
168 15 50509591 52451884 4 2 1.1e-15 3.1e-11 6.6e-03 83 AP4E1 GLDN
169 15 66797492 69178312 6 9 4.4e-16 3.6e-17 NaN NaN AAGAB IQCH MAP2K5 PIAS1 SMAD3
170 15 74138822 76613093 4 2 2.3e-08 1.3e-15 5.1e-18 -17 ARID3B SNUPN
171 15 78032707 79537269 5 1 1.1e-10 5.3e-12 1.2e-02 87 CHRNA3
172 15 82250003 86109582 14 3 2.5e-17 4.0e-13 9.1e-03 87 ALPK3 BTBD1 GOLGA6L9
173 16 86671 1375263 1 1 1.3e-07 4.7e-06 4.4e-01 97 WFIKKN1
174 16 2440033 5627737 23 12 8.8e-34 8.4e-31 1.0e+00 100 CLUAP1 CORO7 IL32 MGC3771 NAT15 NLRC3 UBN1 ZNF200
175 16 8016708 9438692 1 1 1.5e-08 8.4e-09 1.7e-04 57 METTL22
176 16 27655848 29595483 12 1 1.2e-11 3.4e-11 8.0e-02 93 EIF3C
177 16 29711343 31957368 18 1 4.8e-17 3.9e-15 1.9e-01 97 STX1B
178 16 66542957 68548595 5 1 2.1e-10 1.8e-09 1.0e+00 100 ATP6V0D1
179 16 68901284 73789190 15 10 9.2e-18 5.3e-26 NaN NaN COG4 KIAA0174 NFAT5 NOB1 SF3B3 ZFHX3
180 16 77436921 79943873 2 1 3.5e-10 1.9e-11 7.2e-11 6 WWOX
181 16 87190924 87769951 1 1 1.8e-08 1.2e-06 6.1e-08 -24 ZCCHC14
182 16 88030355 89544756 4 2 1.5e-08 1.4e-10 4.8e-05 60 PIEZO1 SNAI3-AS1
183 17 1263564 2900882 1 1 1.1e-07 4.7e-08 9.9e-07 20 SMG6
184 17 6397773 8535817 18 6 1.6e-14 1.3e-14 1.0e+00 100 CHRNB1 CNTROB DLG4 ZBTB4
185 17 15149905 16908991 6 1 1.2e-08 1.6e-08 1.0e+00 100 ZSWIM7
186 17 17017584 18325085 4 1 8.8e-09 6.8e-09 1.0e-01 92 TOM1L2
187 17 26888725 30380381 10 4 5.4e-13 1.7e-26 3.3e-07 77 CRLF3 EVI2A NUFIP2 SSH2
188 17 36710513 38783469 11 1 8.7e-17 8.7e-17 1.0e+00 100 PNMT
189 17 41946180 47357969 46 10 1.0e-56 3.0e-53 1.0e+00 100 ARL17B CDK5RAP3 GFAP HOXB2 LRRC37A2 LRRC37A4P MAPT
190 17 48013115 49468264 1 1 1.8e-07 3.3e-06 4.2e-01 97 ABCC3
191 17 58828402 60172573 3 1 3.1e-20 3.7e-22 1.4e-03 89 C17orf82
192 17 61221773 64438011 7 3 3.4e-17 1.9e-15 8.7e-01 100 CCDC46 PSMC5 SMURF2
193 17 72503355 74267010 9 6 3.6e-12 8.0e-12 NaN NaN GGA3 LLGL2 MIF4GD MRPS7 NUP85
194 17 74438939 75911905 2 2 8.6e-08 3.4e-07 8.5e-06 24 SEC14L1 SEPT9
195 17 78778692 81051007 13 10 3.6e-25 1.8e-26 NaN NaN ACTG1 ASPSCR1 CCDC57 DCXR METRNL PYCR1 STRA13
196 18 69836 910635 1 1 3.1e-12 3.7e-12 1.0e+00 100 USP14
197 18 8010444 9532097 2 1 1.5e-11 9.2e-13 3.4e-03 83 SOGA2
198 18 19692435 21806700 3 2 3.3e-10 5.0e-20 3.4e-08 64 C18orf8 RBBP8
199 18 49172179 51753106 1 1 1.8e-07 8.7e-14 7.4e-09 40 DCC
200 18 52209411 54028036 1 1 2.9e-08 9.5e-12 2.7e-08 33 TCF4
201 19 288246 2923263 3 2 4.6e-11 1.1e-09 4.3e-01 98 DOT1L WDR18
202 19 5210622 6609390 6 1 1.4e-15 1.8e-14 1.0e+00 100 AC104532.4
203 19 9723423 11372077 3 2 6.2e-09 5.6e-10 8.7e-05 60 KRI1 RAVER1
204 19 18283501 18786784 1 1 6.7e-08 6.4e-07 6.1e-07 0 SSBP4
205 19 36113459 37605917 4 1 8.9e-11 1.4e-08 4.3e-01 98 ZFP14
206 19 40259342 41827120 3 1 3.3e-23 1.1e-22 4.0e-02 96 LTBP4
207 19 45187302 47796800 8 4 2.0e-11 3.1e-09 7.7e-02 91 APOC1P1 CALM3 EML2 PNMAL1
208 19 51666972 53087879 1 1 1.5e-07 6.6e-06 6.3e-01 99 ZNF577
209 20 9925555 11347455 1 1 3.0e-07 1.2e-08 1.4e-03 68 JAG1
210 20 20586271 22065466 2 1 1.3e-08 2.2e-07 2.8e-02 82 XRN2
211 20 24230055 26307797 7 1 2.1e-11 2.1e-11 1.3e-01 95 PYGB
212 20 29522520 31494382 7 2 4.6e-14 1.8e-13 1.0e+00 100 HM13 PLAGL2
213 20 31884069 35512648 37 7 1.8e-37 1.1e-39 NaN NaN CPNE1 EPB41L1 GGT7 MAP1LC3A RP4-614O4.11 UQCC
214 20 42495338 43059437 1 1 8.7e-08 4.9e-09 6.0e-05 53 JPH2
215 20 44824099 46516716 1 2 1.8e-12 9.3e-30 3.6e-15 52 EYA2
216 20 46838455 48603940 4 1 1.2e-09 2.2e-11 1.0e+00 100 ARFGEF2
217 20 61522825 62912463 16 8 2.2e-36 1.9e-36 NaN NaN LIME1 OPRL1 RTEL1 SLC2A4RG STMN3
218 21 34750338 36786185 2 3 1.8e-13 1.2e-14 2.3e-04 77 CLIC6 MRPS6
219 22 17581838 19203078 1 1 2.0e-16 7.1e-19 2.0e-04 82 MICAL3
220 22 29439201 31599088 7 3 1.3e-12 4.4e-12 9.7e-02 94 CTA-85E5.10 HORMAD2 SEC14L4
221 22 41720697 43459864 2 2 2.9e-09 1.3e-07 2.1e-02 81 SLC25A5P1 Z83851.1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.2 2 0 0.0 0.00 1.0e+00 GGT7 MRPS33
Bipolar Disorder or Schizophrenia 1.2 9 6 13.3 -0.59 9.5e-02 BRAF CHRNA3 CUL3 DPP3 GGT7 LOC723809 MAD1L1 MRPS33 ZMAT2
Depressed Affect (Nagel 2018) 1.6 9 7 15.6 -0.82 2.0e-03 ARL17B DCC HORMAD2 LRRC37A2 LRRC37A4P MAPT PTCH1 RNF123 TCF4
Depression (Nagel 2018) 1.4 2 0 0.0 0.00 1.0e+00 ARL17B JMJD1C
Intelligence (Savage-Jansen 2018) 1.4 15 12 26.7 0.57 2.1e-02 ARFGEF2 ARL17B CENPW DCAF16 EIF3C FOXO3 FOXP1 JMJD1C LRRC37A2 LRRC37A4P MAPT NR2F1 RNF123 SLC25A5P1 ZMAT2
Neuroticism (Nagel 2018) 1.7 12 7 15.6 -0.69 6.3e-03 ACTG1 ARL17B CENPW DIMT1 HORMAD2 LRRC37A2 LRRC37A4P MAPT PTCH1 STX1B TCF4 UBXN2A
Schizophrenia (2018) 1.1 6 1 2.2 -0.23 6.6e-01 CHRNA3 CUL3 DCC LOC723809 MAD1L1 ZMAT2
Worry (Nagel 2018) 1.5 9 6 13.3 -0.72 1.2e-02 ARL17B CENPW IQCH LRRC37A2 LRRC37A4P MAPT PTCH1 SEMA3B-AS1 STX1B
Alzheimer’s Disease (including proxy) 1.1 1 1 2.2 0.00 1.0e+00 STX1B
Crohns Disease (2017) 1.4 10 7 15.6 -0.86 7.7e-04 CHCHD1 CTSS EIF3C LIME1 P4HA2 PARK7 RTEL1 SDCCAG3 SLC2A4RG STMN3
Irritable Bowel Disease (IBD) 1.5 13 8 17.8 -0.78 5.7e-04 AC016747.3 CERS2 CTSS EIF3C HORMAD2 LIME1 MUC1 P4HA2 PARK7 RTEL1 SDCCAG3 SLC2A4RG STMN3
Ulcerative Colitis (UC) 1.2 4 3 6.7 -0.38 6.2e-01 AC016747.3 PARK7 SDCCAG3 STMN3
Major Depression (MDD) 1.3 1 0 0.0 0.00 1.0e+00 RNF123
Reaction Time 1.3 5 2 4.4 -0.71 1.1e-01 ARL17B DLG4 FOXO3 RMI1 WFIKKN1
Verbal and Numeric Reasoning (VNR) 1.4 11 7 15.6 0.60 3.8e-02 ARFGEF2 DCAF16 EIF3C FOXO3 FOXP1 JMJD1C LRRC37A4P MAPT RNF123 SLC25A5P1 ZMAT2
Breast Cancer 1.5 11 8 17.8 -0.22 4.7e-01 CTC-228N24.3 DIRC3 LRRC37A2 LRRC37A4P MAPT MLLT10 MUC1 PARK7 RIN3 SNUPN SSBP4
Ovarian Cancer 1.4 6 4 8.9 0.98 1.1e-04 CLIC6 HOXB2 LRRC37A2 LRRC37A4P MAPT MLLT10
Prostate Cancer 1.5 4 2 4.4 0.16 8.4e-01 CERS2 LIME1 MDM4 SLC2A4RG
Age at First Birth 1.2 1 1 2.2 0.00 1.0e+00 RNF123
Bipolar Disorder (2011) 2.0 2 0 0.0 0.00 1.0e+00 DPP3 GGT7
Body Mass Index (BMI) (2010) 1.4 3 1 2.2 0.00 1.0e+00 CDK5RAP3 EIF3C IQCH
Coronary Artery Disease (CAD) 1.3 2 1 2.2 0.00 1.0e+00 CARF TCF21
Crohns Disease (2012) 1.4 5 4 8.9 -0.84 3.5e-02 HORMAD2 P4HA2 SDCCAG3 SLC2A4RG STMN3
Mean Putamen Volume 1.1 1 0 0.0 0.00 1.0e+00 HM13
HbA1C 1.1 1 0 0.0 0.00 1.0e+00 ABO
HDL Cholesterol 1.2 6 3 6.7 -0.27 6.1e-01 AFF1 ATP6V0D1 C6orf106 JMJD1C PNMT SIDT2
LDL Cholesterol 1.5 2 1 2.2 0.00 1.0e+00 ABO C6orf106
Lupus 1.1 1 0 0.0 0.00 1.0e+00 TMEM194B
Neuroticism (2016) 1.2 4 2 4.4 -0.98 3.1e-03 LRRC37A2 LRRC37A4P MAPT TCF4
Primary Biliary Cirrhosis 1.1 3 1 2.2 0.00 1.0e+00 CCDC153 LRRC37A4P PNMT
Rheumatoid Arthritis 1.1 1 0 0.0 0.00 1.0e+00 CCDC153
Schizophrenia (2014) 1.1 4 1 2.2 0.72 2.8e-01 CUL3 FOXN2 MAD1L1 RP11-90P5.2
Triglycerides 1.2 3 3 6.7 0.00 1.0e+00 AFF1 JMJD1C SIDT2
Type 2 Diabetes (T2D) (2012) 1.4 1 1 2.2 0.00 1.0e+00 JAZF1
Ulcerative Colitis 1.2 5 3 6.7 -0.78 1.2e-01 LIME1 PARK7 SDCCAG3 SLC2A4RG STMN3
Blood Eosinophil Count 1.3 45 28 62.2 0.22 1.0e-01 AAGAB ABO AC104532.4 ARL17B ATP6V0D1 BANF1 CARF CCDC46 CERS2 CORO7 CRLF3 CTC-228N24.3 CTSS DLG4 EBPL EIF1AD HTR4 IQCH JAZF1 LCT LRRC37A2 LRRC37A4P MAP2K5 MAPT MCM4 MCM6 MRPS21 NFAT5 NOB1 P4HA2 PPARD RIN3 RP11-755F10.1 RP1-244F24.1 RPLP0P2 SDCCAG3 SEMA3B-AS1 SF3B2 SKAP2 SLC2A4RG SLC38A6 SMPD2 SUOX TOM1L2 TSEN2
Blood Platelet Count 1.2 64 48 106.7 -0.09 4.7e-01 ABO ADH1B BIN3 C18orf8 C1orf130 C2orf42 C6orf106 CAB39L CARF CCDC153 CCDC46 CEP120 CERS2 CHRNB1 CHRNG CORO7 CPNE1 CRLF3 CTSS DCAF16 DIMT1 DIP2B DISP2 DSTYK EIF3C EVI2A GFAP GRK4 HM13 JMJD1C LIME1 LMCD1 LRRC37A4P LRRN2 MAPT MSH6 MUC1 P4HA2 PIEZO1 PLAGL2 PNMT PROSER2 RIN3 SAMD4A SCMH1 SEC14L4 SEMA3B-AS1 SIDT2 SLC25A5P1 SLC2A4RG SMG6 SMPD2 SNUPN SSH2 ST7L STMN3 TBPL1 TIGD2 TSEN2 TULP4 VKORC1L1 WFIKKN1 ZNF577 ZNF641
Blood Red Count 1.7 63 52 115.6 -0.21 8.6e-02 ABO AC016725.4 AFF1 AIP AOC1 ARL17B ASPSCR1 B3GNT1 C11orf80 C17orf82 C1orf130 CALM3 CENPW CHP CNIH4 CNTROB CTSF DARS DCXR DOT1L DPP3 DSTYK EIF2AK4 EIF3C GCHFR GSTP1 HM13 HOXB2 JMJD1C KIAA0174 KLRAQ1 LCT LIME1 LRRC37A2 LRRC37A4P LTBP4 MAPT MCM6 MST1P2 MUC1 NFAT5 NOB1 PNMT PSMC5 PYCR1 RIN1 RP11-541N10.3 RPS6KA1 SEMA3B-AS1 SLC25A21 SLC2A4RG SNAI3-AS1 SPRYD4 SSBP4 SSH2 STMN3 STX1B SUPT3H TOM1L2 TSEN2 WFIKKN1 ZBTB4 ZNF641
Blood White Count 1.3 57 38 84.4 -0.26 4.0e-02 ABO AC016747.3 AP4E1 BANF1 BTBD7 C18orf8 C6orf217 CCDC126 CCDC153 CENPW CEP120 CHD7 CLUAP1 CNIH4 CORO7 CTB-36H16.2 CTC-228N24.3 DCAF16 DIP2B DSTYK EIF1AD EIF3C GRK4 HORMAD2 HOXC6 HTR4 JMJD1C KRI1 LEPR LRRC37A2 LRRC37A4P MAP1LC3A MAPT MRPS21 NOB1 NUFIP2 P4HA2 PNMT PPARD PTCH1 RIN3 RMI1 RNF123 RPLP0P2 SCMH1 SDCCAG3 SNUPN SSH2 STMN3 STX1B TNFAIP8 TOM1L2 TULP4 UBXN2A VKORC1L1 ZNF577 ZSWIM7
Heel T-Score 1.9 82 59 131.1 0.11 2.9e-01 AAGAB ABO AFF1 ANAPC10 ANO7P1 AP4E1 ARMS2 ASPSCR1 BMP4 BMP6 C18orf8 CCDC153 CCDC91 CEP120 CHCHD1 CHRNB1 CNIH4 COL21A1 CORO7 CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTSS DCAF16 DCXR DIP2B DIRC3 DIS3L2 DOT1L EBPL EEF1G EPB41L2 EYA2 FIP1L1 FLI1 GGT7 GLDN HLX HOXC10 HOXC6 HSPA4 IPO8 IQCH JAG1 KIAA0174 LEAP2 LIME1 LIN28B LRRC37A2 LRRC37A4P MAP1LC3A MAP2K5 MAPT MCM4 MRPL21 MRPS35 MSH6 MUC1 PKDCC RIN3 RIOK1 RP11-250B2.6 RP11-860B13.1 RP11-967K21.1 RPS20 SCMH1 SKAP2 SLC2A4RG SNAI3-AS1 SSBP4 SSH2 ST7L STRA13 STX1B SYT14 TRAF3IP1 TSPAN9 TULP4 TWIST1 WNT4 ZBTB4 ZNF641
BMI 1.7 57 38 84.4 -0.35 4.2e-03 AP3B1 ARFGEF2 BTBD7 C17orf82 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CHRNB1 CLUAP1 CTD-2201E18.3 CYTL1 DCAF16 DIS3L2 EIF2AK4 EIF3C EML2 FOXO3 FOXP1 GGT7 GRK4 HLX HTR4 IQCH JAZF1 JMJD1C KIAA1598 MAP2K5 MLLT10 MRPL21 MST1P2 NFAT5 NLRC3 NOB1 NOP58 NR2F1 NR3C1 PRKG1 PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SEMA3B-AS1 SF3B3 SLC25A5P1 SPRYD4 SSH2 STMN3 STRA13 STX1B SUOX SYT14 UBN1 ZCCHC24 ZMAT2 ZSWIM7
Height 3.7 178 156 346.7 -0.12 9.7e-02 AAGAB ABO AC062029.1 ACTG1 AIP ALDH6A1 ANAPC10 AOC1 AP3B1 AP4E1 ARFGEF2 ARL17B ARMS2 ASPSCR1 ATOH7 ATP6V0D1 B3GNT7 BANF1 BMF BMP6 BOK BRAF C10orf11 C17orf82 C18orf8 C2orf42 C2orf54 C6orf106 CARF CCDC126 CCDC87 CCDC91 CDK5RAP3 CENPW CEP120 CHD7 CHP CHRNB1 CHRNG CNIH4 CNTROB COG4 COPS7B CPE CPNE1 CPZ CRLF3 CTA-85E5.10 CTC-228N24.3 CYTL1 DCAF16 DCC DCXR DIP2B DIS3L2 DISP2 DOT1L EBPL EFEMP1 EIF1AD EIF2AK4 EPB41L1 ERC1 EVI2A FAM53A FLI1 FOXN2 FOXO3 GCHFR GFAP GGT7 GLB1 GSTP1 HLX HM13 HORMAD2 IPO8 IQCH ISCA2 JAG1 JAZF1 JMJD1C KLRAQ1 LIME1 LIN28B LLGL2 LMCD1 LRRC37A2 LRRC37A4P LTBP1 LTBP4 MAP1LC3A MAPT MCM4 MDM4 MIF4GD MRPS21 MRPS33 MRPS35 MRPS6 MST1P2 MUC1 NDST1 NDUFB2 NDUFB2-AS1 NFAT5 NOB1 NOL8 NOP58 NR3C1 NUFIP2 P4HA2 PARK7 PBLD PDIK1L PIBF1 PIEZO1 PPIAL4C PRDM11 PROSER2 PSMC5 PTCH1 PYCR1 PYGB QSOX2 RAB7L1 RAD18 RAVER1 RBBP8 RMI1 RP11-171I2.2 RP11-477D19.2 RP11-529H20.5 RP11-755F10.1 RP11-860B13.1 RP11-90P5.2 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 RRP15 RTEL1 SAMD4A SCMH1 SDCCAG3 SEMA3B-AS1 SENP6 SF3B2 SLC25A21 SLC2A4RG SMAD3 SMG6 SMPD2 SMURF2 SNAI3-AS1 SNUPN SNX13 SSBP4 ST7L STRA13 SUSD5 TBC1D30 TCF4 THBS2 TMTC4 TMUB1 TOM1L2 TRAF3IP1 TSEN2 TULP4 UBXN2A UQCC VKORC1L1 WFIKKN1 WNT4 WWOX ZBTB4 ZNF641
Waist Hip Ratio (WHR) 2.5 65 44 97.8 -0.38 4.6e-04 AAGAB AC004540.4 ANAPC10 AP3B1 ARID5B ASPSCR1 BANF1 C17orf82 CENPW CFHR3 CHRNB1 CNTROB CORO7 CTC-228N24.3 CYTL1 DISP2 DOT1L DSTYK EEF1G EIF1AD EYA2 FLJ12825 GGT7 HLX HOXC10 HOXC6 HSPA4 IQCH JAZF1 LEAP2 LOC723809 LRRC37A2 LRRC37A4P MAP2K5 MAPT MRPS35 MRPS7 MSH6 MST1P2 MUC1 NFAT5 NLRC3 NOL8 NUP85 OPRL1 PLCE1 PSMC5 PYCR1 RAVER1 RP11-23P13.7 RP11-250B2.6 RP11-529H20.5 RP11-64K12.8 SEMA3B-AS1 SF3B2 SNUPN TNFAIP8 TOM1L2 TSEN2 UQCC WNT4 ZBTB4 ZCCHC24 ZNF200 ZSWIM7
Systolic Blood Pressure 1.5 52 28 62.2 -0.18 1.9e-01 AC016725.4 ADAMTS8 ARFGEF2 BMP4 BMP6 C17orf82 CAMK1D CARF CDC123 CEP120 CHP CHRNB1 CLUAP1 COL21A1 CORO7 CTC-228N24.3 DCAF16 DCLK2 DLG4 EFEMP1 EIF2AK4 EPB41L2 FLJ12825 FOXO3 GCHFR HOXC6 HSPA4 HTR4 LIME1 LRRC37A2 LRRC37A4P MAPT NAT15 OPRL1 RIN3 RNF123 RP11-541N10.3 RP11-90P5.2 SF3B3 SIDT2 SLC12A2 SLC2A4RG SMG6 TCF21 TMBIM1 TMEM194B TNFAIP8 UBN1 UBXN2A UQCC ZMAT2 ZNF641
Smoking Status 1.7 15 1 2.2 0.46 5.6e-02 FOXP1 IQCH KIAA1598 MAP1LC3A MAP2K5 MLLT10 MSH6 NUFIP2 PLAGL2 RNF123 SLC25A5P1 SUOX USP14 WFIKKN1 ZFHX3
Allergy or Eczema 1.4 14 8 17.8 -0.34 2.1e-01 BANF1 C6orf106 C6orf217 CTSF EIF1AD GCHFR IQCH JAZF1 LIME1 MRPS33 RIN3 SLC2A4RG STMN3 SUOX
Cardiovascular Disease 1.5 23 9 20.0 -0.49 1.5e-02 C17orf82 C18orf8 C1GALT1 CHP CTC-228N24.3 DCAF16 DLG4 GCHFR HOXC6 HTR4 MAP2K5 NFAT5 NOP58 OPRL1 RP11-613D13.5 SF3B3 SIDT2 SLC12A2 STX1B TCF21 TMBIM1 XRN2 ZNF641
Hypothyroidism (self reported) 1.1 7 5 11.1 -0.45 3.2e-01 ARID5B ARMS2 C6orf217 FKBP5 HORMAD2 SUOX TMEM194B
Respiratory disease 1.8 13 10 22.2 0.08 7.6e-01 AAGAB C6orf217 CARF CCDC153 IQCH MAP2K5 P4HA2 PNMT RIN3 RNF123 SLC2A4RG STMN3 SUOX
Type 2 Diabetes (T2D) (2018) 1.7 9 6 13.3 -0.78 1.3e-02 CAMK1D CENPW EML2 JAZF1 NFAT5 NOB1 RNF123 SNUPN ZCCHC24
Lung FEV1/FVC ratio 2.9 73 54 120.0 -0.27 1.7e-02 ABLIM3 ACTG1 ARID5B ARMS2 ATP6V0D1 BIN3 BMF BMP4 BTBD1 C10orf11 C1GALT1 C6orf106 CAMK1D CARF CCDC171 CDC123 CENPW CEP120 CFHR3 CHCHD1 CHP CHRNA3 CTA-85E5.10 CTC-228N24.3 DSP EFEMP1 EIF2AK4 ERC1 FLJ12825 FOXN2 FOXO3 GPD2 HLX HOXC6 HTR4 INTS12 IQCH ITGA2 JMJD1C KCNQ5 LLGL2 LMCD1 LONRF2 LRRC37A4P LTBP4 MAP1LC3A MICAL3 MLLT10 MRPS35 MRPS6 MST1P2 P4HA2 PAIP1 PAK6 PTCH1 RAB7L1 RMI1 RP11-23P13.7 RPS20 RRP15 SLC38A6 SLMAP SMURF2 SOGA2 SSH2 STARD10 STRA13 SUOX TIGD2 TMUB1 TRAF3IP1 ZFHX3 ZFP14
Neuroticism 1.8 13 8 17.8 -0.82 9.2e-05 AAGAB ACTG1 ARL17B CENPW HORMAD2 IQCH LRRC37A2 LRRC37A4P MAP2K5 MAPT PTCH1 TCF4 UBXN2A
Chronotype (morning person) 1.4 6 6 13.3 -0.56 1.9e-01 CERS2 MRPS21 SDCCAG3 SEMA3B-AS1 SLC25A5P1 TRAF3IP1
Hair Pigment 0.7 36 26 57.8 0.43 5.2e-03 ACTG1 AIP ASPSCR1 BRAF BTBD1 C11orf80 C2orf42 C6orf106 CCDC57 CDK5RAP3 CPNE1 CTC-228N24.3 DCXR DSTYK EPB41L1 FOXO3 GGT7 HM13 JAZF1 LRRN2 MAP1LC3A MAPT MRPL21 MSH6 NNT PIEZO1 PYCR1 RP4-614O4.11 SNAI3-AS1 SSBP4 STRA13 TBC1D30 TULP4 TWIST1 UQCC ZCCHC24
Tanning 1.0 17 13 28.9 -0.54 2.0e-02 ACTG1 CERS2 CORO7 CPNE1 CTSS DSTYK EPB41L1 GGT7 JAZF1 MAP1LC3A NOX4 PIEZO1 PLAGL2 RP11-64K12.8 RP4-614O4.11 SNAI3-AS1 UQCC
Hand grip strength (left) 2.4 31 18 40.0 0.37 3.5e-02 AC016725.4 AOC1 ARFGEF2 ARL17B BANF1 BRAF CCDC87 DARS DCAF16 DOT1L FOXP1 GFAP HOXB2 JAG1 LIN28B LRRC37A2 LRRC37A4P MAP1LC3A MAPT NFAT5 NOB1 P4HA2 PKDCC PSMC5 RAB7L1 RP11-171I2.2 RP4-614O4.11 STX1B TCF4 UQCC WDR18
Number of treatments/medications taken 1.3 2 1 2.2 0.00 1.0e+00 MLLT10 RNF123
Sensitivity / hurt feelings 1.5 5 5 11.1 -0.81 2.7e-02 ARL17B LRRC37A2 LRRC37A4P MAPT PTCH1
Frequency of depressed mood in last 2 weeks 1.4 1 0 0.0 0.00 1.0e+00 LRRC37A2
Hearing difficulty/problems: Yes 1.3 1 1 2.2 0.00 1.0e+00 ABLIM3
Relative age of first facial hair 1.8 10 5 11.1 -0.81 2.8e-03 CCDC46 CHRNG FOXO3 GGT7 LIN28B LRRC37A2 LRRC37A4P MAPT SEMA3B-AS1 TWIST1
Ever used hormone-replacement therapy (HRT) 1.0 1 0 0.0 0.00 1.0e+00 BCDIN3D
Systolic blood pressure, automated reading 1.5 25 14 31.1 0.02 9.4e-01 AC016725.4 ADAMTS8 C17orf82 CAMK1D CHRNB1 COL21A1 CTC-228N24.3 DCAF16 DLG4 EIF2AK4 GCHFR HTR4 LRRC37A2 LRRC37A4P MAPT NAT15 OPRL1 PRDM11 RP11-541N10.3 SLC12A2 SLC2A4RG SMG6 STMN3 TMEM194B UBXN2A
Angina 1.2 1 1 2.2 0.00 1.0e+00 TCF21
Medication for hormone replacement therapy 1.0 1 0 0.0 0.00 1.0e+00 RP1-199J3.5
Medication: Metformin 1.5 4 2 4.4 -1.00 1.9e-03 CAMK1D JAZF1 SNUPN ZCCHC24
Diabetes (mother) 1.4 1 1 2.2 0.00 1.0e+00 CAMK1D
Pack years adult smoking proportion 1.7 2 1 2.2 0.00 1.0e+00 CHRNA3 JMJD1C
Impedance of leg (right) 2.3 56 36 80.0 -0.25 5.3e-02 ABO AOC1 AP3B1 C11orf80 C6orf106 CEP120 CLUAP1 CPNE1 CTC-228N24.3 CTSF CTSS DIP2B DPP3 EIF3C EML2 EPB41L1 FLJ12825 GGT7 GLB1 HLX HOXC6 JAZF1 JPH2 LIN28B LRRC37A4P LTBP1 MAP1LC3A MRPL21 MST1P2 MUC1 NLRC3 NOL8 PIAS1 PLCE1 PSMC5 RAVER1 RIN1 RIN3 RNF123 RP11-23P13.7 RP11-90P5.2 RP4-614O4.11 RPS20 SEMA3B-AS1 SLC12A2 SLC2A4RG SMG6 SNAI3-AS1 STX1B SUOX SUPT3H TOM1L2 UQCC WNT4 ZNF641 ZSWIM7
Leg fat-free mass (left) 2.7 66 47 104.4 -0.14 2.4e-01 ACTG1 ANAPC10 AOC1 AP3B1 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CDK5RAP3 CENPW CEP120 CHP CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 GLB1 HORMAD2 IPO8 IQCH KIAA1598 MAP1LC3A MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 SCMH1 SLC12A2 SMPD2 STX1B SUOX SUPT3H TULP4 UQCC WNT4 ZSWIM7
Trunk fat percentage 2.1 48 31 68.9 -0.28 3.9e-02 AAGAB AC016725.4 AIP AP3B1 ARL17B C18orf8 C6orf106 CCDC171 CDK5RAP3 CENPW CHRNB1 DARS DIP2B EEF1G EFEMP1 EIF3C FKBP5 FOXO3 FOXP1 GFPT1 GRK4 GSTP1 HOXC6 HTR4 IQCH KIAA1598 LCT LIME1 LRRC37A2 LRRC37A4P MAP2K5 MAPT MCM6 MLLT10 NFAT5 NOB1 PPARD PYGB RIN3 RMI1 RP11-613D13.5 RP1-283E3.4 SLC2A4RG SMAD3 SSH2 ST7L STX1B SYT14
Hand grip strength (right) 2.4 29 14 31.1 0.25 1.8e-01 AC016725.4 AOC1 ARFGEF2 ARL17B CHRNB1 CPNE1 DARS DCAF16 DOT1L EIF3C GFAP HOXB2 JAG1 LIN28B LRRC37A2 LRRC37A4P MAP1LC3A MAPT NFAT5 NOB1 P4HA2 PSMC5 RAB7L1 RP11-171I2.2 RP11-317J10.2 RP4-614O4.11 SCMH1 TULP4 UQCC
Current tobacco smoking 1.3 3 1 2.2 0.00 1.0e+00 CARF CUL3 STMN3
Fed-up feelings 1.4 4 4 8.9 -0.85 7.0e-02 DCC LRRC37A2 LRRC37A4P MAPT
Relative age voice broke 1.6 7 4 8.9 -0.60 8.9e-02 FOXO3 LIN28B LRRC37A2 LRRC37A4P MAPT SCMH1 UQCC
Taking other prescription medications 1.4 1 1 2.2 0.00 1.0e+00 RNF123
Age when periods started (menarche) 2.0 14 9 20.0 -0.24 3.3e-01 AC016747.3 CENPW CHP FOXO3 GGT7 IQCH LIN28B MAP2K5 MSH6 NFAT5 NOB1 RAVER1 RP11-422P24.10 SEMA3B-AS1
Bilateral oophorectomy (both ovaries removed) 1.2 1 1 2.2 0.00 1.0e+00 WNT4
Heel bone mineral density (BMD) T-score, automated (left) 1.5 6 3 6.7 -0.04 9.5e-01 BMP4 EBPL GGT7 PKDCC ST7L WNT4
High blood pressure 1.5 10 4 8.9 -0.27 4.5e-01 CHRNB1 DCAF16 DLG4 GCHFR HOXC6 HTR4 MAP2K5 NAT15 OPRL1 STX1B
Hayfever, allergic rhinitis or eczema 1.3 8 2 4.4 -0.45 2.3e-01 C6orf106 C6orf217 GCHFR MRPS33 P4HA2 RIN3 STMN3 SUOX
Medication: Levothyroxine sodium 1.1 4 2 4.4 -0.99 1.1e-02 C6orf217 FKBP5 HORMAD2 SUOX
Sitting height 3.7 102 83 184.4 0.03 7.6e-01 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARID3B ARL17B ASPSCR1 ATOH7 BMP6 BOK C18orf8 C6orf106 CCDC126 CCDC171 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 CNTROB COG4 COPS7B CORO7 CPE CPNE1 CPZ CRLF3 DCAF16 DCC DCXR DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EPB41L1 ERC1 EYA2 FAM53A FOXO3 GFAP GGT7 GLB1 HM13 HORMAD2 JAG1 JAZF1 LRRC37A2 LRRC37A4P LTBP1 MAP1LC3A MAPT MRPS21 MST1P2 NDUFB2 NFAT5 NOB1 P4HA2 PARK7 PBLD PDIK1L PKDCC PLAGL2 PROSER2 PSMC5 PTCH1 PYCR1 PYGB QSOX2 RAB7L1 RP11-171I2.2 RP11-250B2.6 RP11-529H20.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 RRP15 SAMD4A SCMH1 SDCCAG3 SENP6 SLC25A21 SMAD3 SMPD2 SNAI3-AS1 SNUPN SNX13 SUPT3H TBC1D30 TULP4 UBXN2A UQCC WFIKKN1 WNT4 ZBTB4 ZNF438 ZNF641 ZSWIM7
Chronic bronchitis/emphysema (father) 1.5 2 1 2.2 0.00 1.0e+00 CHRNA3 IQCH
High blood pressure (mother) 1.3 1 1 2.2 0.00 1.0e+00 FLJ12825
Body mass index (BMI) 1.6 36 20 44.4 -0.67 6.4e-06 AC016725.4 AP3B1 ARFGEF2 BTBD7 C18orf8 C6orf106 CALML6 CCDC171 CCDC87 CDK5RAP3 CLUAP1 DCAF16 EIF3C FOXO3 FOXP1 GGT7 GRK4 HTR4 IQCH JAZF1 JMJD1C KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NLRC3 NOB1 RNF123 RP11-613D13.5 RP1-283E3.4 STX1B SUOX SYT14 ZSWIM7
Impedance of leg (left) 2.4 54 38 84.4 -0.19 1.6e-01 ABO AOC1 AP3B1 C11orf80 C6orf106 CEP120 CLUAP1 CPNE1 CTC-228N24.3 CTSF CTSS DIP2B DPP3 EIF3C EML2 EPB41L1 FLJ12825 GGT7 GLB1 HLX HOXC6 JAZF1 JPH2 LIME1 LRRC37A2 LRRC37A4P LTBP1 MAP1LC3A MRPL21 MST1P2 MUC1 NFAT5 NLRC3 NOL8 PIAS1 PSMC5 RAVER1 RIN1 RIN3 RNF123 RP11-90P5.2 RP4-614O4.11 RPS20 SEMA3B-AS1 SLC12A2 SLC29A2 SLC2A4RG STX1B SUOX SUPT3H TOM1L2 UQCC WNT4 ZNF641
Leg predicted mass (left) 2.7 65 47 104.4 -0.14 2.7e-01 ACTG1 ANAPC10 AOC1 AP3B1 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CDK5RAP3 CENPW CEP120 CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 GLB1 HORMAD2 IPO8 IQCH KIAA1598 MAP1LC3A MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 SCMH1 SLC12A2 SMPD2 STX1B SUOX SUPT3H TULP4 UQCC WNT4 ZSWIM7
Trunk fat mass 2.1 48 33 73.3 -0.38 4.4e-03 AAGAB AC016725.4 AIP ANAPC10 AP3B1 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CTD-2201E18.3 DLG4 EFEMP1 EIF2AK4 EIF3C EPB41L1 FKBP5 FOXO3 FOXP1 GGT7 GSTP1 HTR4 IQCH KIAA1598 LCT LIN28B LRRC37A2 MAP1LC3A MAP2K5 MAPT MCM6 MLLT10 NFAT5 NOB1 NR3C1 PPARD PYGB RNF123 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 SLC2A4RG SMAD3 SSH2 ST7L STX1B SYT14 UQCC
Waist circumference 1.9 36 24 53.3 -0.48 1.6e-03 AAGAB AC004540.4 AIP AP3B1 BTBD7 C18orf8 C6orf106 CALML6 CCDC171 CDK5RAP3 CEP120 CPNE1 DLG4 EIF3C EPB41L1 FOXO3 GGT7 GRK4 GSTP1 HOXC6 HTR4 IQCH KIAA1598 MAP2K5 MLLT10 NFAT5 NOB1 NR3C1 PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SLC2A4RG STX1B SYT14 ZCCHC24
Number of incorrect matches in round 1.2 2 0 0.0 0.00 1.0e+00 AC016725.4 STX1B
Past tobacco smoking 1.7 6 3 6.7 -0.83 8.1e-04 GGT7 IQCH MAP1LC3A MAP2K5 MSH6 NOB1
Alcohol usually taken with meals 1.4 2 1 2.2 0.00 1.0e+00 CHRNB1 FOXP1
Nervous feelings 1.6 4 3 6.7 -0.99 4.8e-04 CENPW LRRC37A2 LRRC37A4P MAPT
Frequency of tenseness / restlessness in last 2 weeks 1.4 5 4 8.9 -0.99 2.9e-05 ARL17B LRRC37A2 LRRC37A4P MAPT RNF123
Hearing difficulty/problems with background noise 1.3 4 0 0.0 -0.76 2.4e-01 LIN28B LRRC37A2 LRRC37A4P MAPT
Hair/balding pattern: Pattern 2 1.6 6 3 6.7 -0.53 2.8e-01 C10orf11 CCDC46 CENPW LRRC37A2 LRRC37A4P TWIST1
Forced vital capacity (FVC) 5.6 152 96 213.3 0.93 1.6e-76 AAGAB ABLIM3 ABO AC016725.4 AC073834.3 AC079742.4 AC104532.4 ANAPC10 ANGPTL1 AOC1 AP3B1 AP4E1 APOC1P1 ARFGEF2 ARID3B ARID5B ARL17B ARMS2 ASPSCR1 BANF1 BCDIN3D BMF BOK BRAF BTBD1 C10orf11 C2orf42 C2orf54 C6orf217 CAMK1D CARF CCDC126 CCDC171 CCDC87 CDC123 CENPW CEP120 CHCHD1 CHRNA3 CLIC6 CLUAP1 COG4 CPE CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTSS CUL3 DARS DCAF16 DCXR EBPL EEF1G EFEMP1 EIF1AD EIF2AK4 EML2 EPB41L2 ERC1 EYA2 FOXN2 FOXP1 GFAP GOLGA6L9 GRK4 HORMAD2 HS2ST1 HTR4 IGFBP7 INTS12 IPO8 IQCH JAG1 KDR LCT LIME1 LMCD1 LONRF2 LRPAP1 LRRC37A2 LRRC37A4P LTBP4 MAP2 MAP2K5 MAPT MCM6 MDM4 METTL22 MLLT10 MRPL21 MRPS35 MST1P2 MUC1 NDUFB2 NDUFB2-AS1 NFAT5 NLRC3 NOB1 NOP58 NOX4 PDIK1L PKDCC PNMT PPARD PPIAL4C PRDM11 PSMC5 PTCH1 PYCR1 PYGB QSOX2 RAB3IL1 RAVER1 RIN3 RNF123 RP11-250B2.6 RP11-541N10.3 RP11-64K12.8 RP11-967K21.1 RPS20 RPS6KA1 RRP15 SCMH1 SEC14L1 SENP6 SF3B2 SHROOM3 SLC12A2 SLC25A21 SLC2A4RG SLMAP SMG7 SMPD2 SMURF2 SNAI3-AS1 SNUPN SSH2 STMN3 STX1B SUSD5 TBC1D30 TCP11L1 THBS2 TULP4 UBXN2A UQCC USP14 WDR18 WNT4 ZCCHC24 ZMAT2 ZNF438
Heel bone mineral density (BMD) T-score, automated (right) 1.5 5 4 8.9 0.64 2.4e-01 BMP4 HOXC10 PKDCC ST7L WNT4
Ever unenthusiastic/disinterested for a whole week 1.2 3 1 2.2 0.00 1.0e+00 LRRC37A2 LRRC37A4P ZMAT2
Qualifications: None of the above 1.3 7 5 11.1 0.32 4.4e-01 BCDIN3D EIF3C FOXO3 FOXP1 JMJD1C RNF123 SUOX
Mouth/teeth dental problems 1.3 2 0 0.0 0.00 1.0e+00 LCT MCM6
Heart attack 1.3 2 0 0.0 0.00 1.0e+00 TCF21 TOM1L2
Allergy 1.5 15 8 17.8 0.09 7.2e-01 AAGAB ABO C6orf106 CCDC153 CHP GCHFR IQCH JAZF1 LIME1 MAP2K5 P4HA2 RIN3 SLC2A4RG STMN3 SUOX
Diabetes (self-reported) 1.7 6 2 4.4 -0.99 3.8e-06 CAMK1D CTC-228N24.3 JAZF1 NFAT5 SNUPN ZCCHC24
Medication: Simvastatin 1.3 2 1 2.2 0.00 1.0e+00 ABO OPRL1
Fluid intelligence score 1.3 5 4 8.9 0.70 1.2e-01 DCAF16 EIF3C FOXO3 FOXP1 RNF123
Illnesses of siblings 1.2 1 0 0.0 0.00 1.0e+00 STX1B
Neuroticism score 1.6 11 6 13.3 -0.86 1.4e-04 ARL17B HORMAD2 LRRC37A2 LRRC37A4P MAPT PTCH1 RNF123 SEMA3B-AS1 TCF4 UBN1 UBXN2A
Weight 2.2 65 40 88.9 -0.34 3.8e-03 AAGAB AIP ANAPC10 AP3B1 ARMS2 BOK BTBD7 C17orf82 C18orf8 C6orf106 CCDC171 CDK5RAP3 CENPW CEP120 CHRNG COPS7B CPNE1 CRLF3 DCAF16 DOT1L EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 GSTP1 HTR4 IQCH KIAA1598 LCT MAP1LC3A MAP2K5 MCM6 MLLT10 MRPL21 MUC1 NFAT5 NR2F1 NR3C1 P4HA2 PARK7 PSMC5 PYGB RAB7L1 RNF123 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 RP4-614O4.11 RPS20 SCMH1 SENP6 SLC25A5P1 SLC2A4RG SMPD2 STX1B SUOX SYT14 UQCC WNT4 ZMAT2 ZSWIM7
Impedance of arm (right) 1.7 46 38 84.4 -0.08 5.9e-01 AOC1 ARL17B C6orf106 CENPW CEP120 CERS2 CPNE1 CPZ CTSS DIP2B EEF1G EFEMP1 EVI2A FOXO3 GGT7 HLX HOXC6 JAZF1 JMJD1C LIME1 LIN28B LRPAP1 LRRC37A2 LRRC37A4P MAP1LC3A MAPT MLLT10 MST1P2 MUC1 NOL8 NUFIP2 PIAS1 PSMC5 RAVER1 RIN3 RMI1 RNF123 RPS20 SCMH1 SEMA3B-AS1 SLC2A4RG SMAD3 ST7L STX1B SUOX ZNF641
Arm fat percentage (right) 1.9 41 26 57.8 -0.41 4.4e-03 AAGAB ABO AC016725.4 AP3B1 ARFGEF2 C17orf82 C18orf8 C6orf106 CARF CCDC171 CCDC87 CDK5RAP3 CENPW CHRNB1 DCAF16 DLG4 EIF3C FKBP5 FOXP1 GRK4 HTR4 IQCH KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NOB1 NOP58 PPARD PYGB RNF123 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 SLC2A4RG SMAD3 SSH2 STX1B SYT14
Trunk fat-free mass 3.0 81 65 144.4 -0.20 6.3e-02 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 B3GNT7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 CNTROB COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 HORMAD2 IPO8 JAZF1 LIN28B MAP1LC3A MRPL21 MST1P2 MUC1 NDUFB2 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 QSOX2 RAB7L1 RAVER1 RIN3 RNF123 RP11-477D19.2 RP11-529H20.5 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC25A5P1 SMPD2 SNAI3-AS1 SNUPN SNX13 SUOX TBC1D30 TULP4 UBXN2A UQCC WNT4 ZBTB4
Hip circumference 1.9 49 33 73.3 -0.43 1.3e-03 AC016725.4 ANAPC10 AP3B1 BOK BTBD7 C18orf8 C2orf54 C6orf106 CCDC171 CDK5RAP3 CEP120 CPNE1 CRLF3 DCXR DLG4 DOT1L EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A EYA2 FAM53A FOXO3 GGT7 HTR4 IQCH KIAA1598 MAP1LC3A MAP2K5 MLLT10 NFAT5 NLRC3 NOB1 NR3C1 RNF123 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 SENP6 SLC2A4RG SMAD3 STMN3 STX1B SYT14 UQCC WNT4 ZMAT2 ZSWIM7
Alcohol intake versus 10 years previously 1.2 1 1 2.2 0.00 1.0e+00 LEAP2
Father's age at death 1.1 1 1 2.2 0.00 1.0e+00 CHRNA3
Worrier / anxious feelings 1.3 5 4 8.9 -0.69 1.3e-01 LRRC37A2 LRRC37A4P MAPT PTCH1 TCF4
Hair/balding pattern: Pattern 3 1.7 7 5 11.1 0.68 4.3e-02 ARL17B CENPW LRRC37A2 LRRC37A4P MAP1LC3A MAPT TWIST1
Number of live births 1.4 4 1 2.2 -0.93 7.3e-02 KIAA1598 LRRC37A4P WNT4 ZFP14
Forced expiratory volume in 1-second (FEV1) 5.0 108 75 166.7 0.94 1.0e-60 ABLIM3 ABO AC016725.4 AC073834.3 AC104532.4 ANAPC10 ANGPTL1 AOC1 AP3B1 APOC1P1 ARFGEF2 ARID3B ARL17B ASPSCR1 BOK BRAF BTBD1 C10orf11 C1GALT1 C2orf42 C6orf217 CAMK1D CCDC126 CCDC171 CCDC87 CDC123 CENPW CEP120 CHCHD1 CHRNA3 CLUAP1 COG4 CTA-85E5.10 CTB-36H16.2 CTSS DARS DCAF16 DCXR EBPL EEF1G EFEMP1 EIF1AD FOXP1 GOLGA6L9 GPD2 GRK4 HORMAD2 HSPA4 HTR4 IGFBP7 INTS12 IPO8 JAG1 LLGL2 LONRF2 LRPAP1 LRRC37A2 LRRC37A4P MAPT MCM6 MDM4 MICAL3 MRPL21 MST1P2 NDUFB2 NFAT5 NOB1 PDIK1L PKDCC PLAGL2 PPARD PPIAL4C PRDM11 PSMC5 PTCH1 PYCR1 PYGB QSOX2 RAB3IL1 RIN3 RNF123 RP11-541N10.3 RP11-967K21.1 RPS6KA1 SCMH1 SF3B2 SF3B3 SH3RF1 SLC25A21 SLC2A4RG SLMAP SMG7 SMPD2 SMURF2 SNAI3-AS1 SNUPN SOGA2 STMN3 STX1B SUOX SUSD5 TBC1D30 TCP11L1 THBS2 TULP4 UBXN2A WNT4 ZCCHC24
Pulse rate 1.1 4 3 6.7 -0.53 4.7e-01 B3GNT7 CEP120 TCF21 TOM1L2
Qualifications: A levels/AS levels or equivalent 1.3 5 3 6.7 0.50 3.1e-01 GPD2 JMJD1C LRRC37A4P RNF123 UQCC
Mouth/teeth dental problems: Dentures 1.3 3 0 0.0 0.00 1.0e+00 CHRNA3 EIF2AK4 MUC1
Asthma 1.7 10 7 15.6 0.06 8.6e-01 AAGAB HTR4 IQCH MAP2K5 P4HA2 PNMT RIN3 SLC2A4RG STMN3 SUOX
Medication: Ibuprofen (e.g. Nurofen) 1.1 2 0 0.0 0.00 1.0e+00 LRRC37A4P MAPT
Medication: Cholesterol lowering 1.2 4 1 2.2 -0.99 6.0e-03 ABO NOP58 OPRL1 SIDT2
Lung cancer (father) 1.3 1 1 2.2 0.00 1.0e+00 CHRNA3
Forced expiratory volume in 1-second (FEV1), Best measure 4.8 102 66 146.7 0.94 1.5e-53 ABLIM3 ABO AC073834.3 ANAPC10 ANGPTL1 AOC1 AP3B1 AP4E1 ARFGEF2 ARL17B ASPSCR1 BOK BRAF BTBD1 C10orf11 C1GALT1 C2orf54 CAMK1D CCDC126 CCDC87 CDC123 CENPW CEP120 CHCHD1 CHRNA3 CLUAP1 COG4 CTA-85E5.10 CTB-36H16.2 CTSS DARS DCAF16 DCXR EBPL EEF1G EFEMP1 FKBP5 FOXP1 GFAP GOLGA6L9 GRK4 HORMAD2 HSPA4 HTR4 INTS12 IPO8 JAG1 LLGL2 LONRF2 LRPAP1 LRRC37A2 LRRC37A4P LTBP4 MAPT MCM6 MDM4 MICAL3 MRPL21 MST1P2 NFAT5 NOB1 PAIP1 PDIK1L PKDCC PLAGL2 PNMT PPARD PPIAL4C PRDM11 PSMC5 PTCH1 PYCR1 PYGB QSOX2 RAB3IL1 RIN3 RNF123 RP1-137D17.1 RP11-967K21.1 RP4-614O4.11 RPS6KA1 SCMH1 SH3RF1 SLC25A21 SLC2A4RG SLMAP SMG7 SMPD2 SMURF2 SNAI3-AS1 SNUPN SOGA2 STX1B SUOX TBC1D30 TCP11L1 THBS2 TULP4 UBXN2A WNT4 ZCCHC24 ZMAT2
Impedance of arm (left) 1.7 48 37 82.2 -0.04 8.0e-01 AOC1 ARL17B C18orf8 CENPW CEP120 CERS2 CPNE1 CPZ CTSS DIP2B EEF1G EFEMP1 EVI2A FOXO3 GGT7 HLX HOXC10 HOXC6 JAZF1 JMJD1C LIME1 LIN28B LRRC37A2 LRRC37A4P MAP1LC3A MAPT MLLT10 MST1P2 MUC1 NOL8 NUFIP2 PIAS1 PNMAL1 PSMC5 RAVER1 RIN3 RMI1 RNF123 RP11-529H20.5 RPS20 SAMD4A SCMH1 SEMA3B-AS1 SLC2A4RG SMAD3 STX1B SUOX ZNF641
Arm fat mass (right) 1.8 37 24 53.3 -0.58 6.7e-05 AAGAB AC016725.4 AP3B1 C18orf8 C6orf106 CCDC171 CCDC87 CDK5RAP3 CEP120 CLUAP1 DLG4 EIF3C EPB41L1 FOXO3 FOXP1 GGT7 GRK4 HTR4 IQCH KIAA1598 LCT MAP1LC3A MAP2K5 MCM6 MLLT10 NFAT5 NLRC3 NOB1 PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SSH2 STX1B SYT14 UQCC ZSWIM7
Trunk predicted mass 3.0 81 65 144.4 -0.20 6.3e-02 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 B3GNT7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 CNTROB COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 HORMAD2 IPO8 JAZF1 LIN28B MAP1LC3A MRPL21 MST1P2 MUC1 NDUFB2 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 QSOX2 RAB7L1 RAVER1 RIN3 RNF123 RP11-477D19.2 RP11-529H20.5 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC25A5P1 SMPD2 SNAI3-AS1 SNUPN SNX13 SUOX TBC1D30 TULP4 UBXN2A UQCC WNT4 ZBTB4
Standing height 3.6 130 109 242.2 -0.15 6.9e-02 AAGAB AC062029.1 ACTG1 AIP ALDH6A1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ARMS2 ATOH7 B3GNT7 BANF1 BMP6 BOK BRAF C17orf82 C18orf8 C6orf106 CCDC126 CCDC87 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 CNTROB COG4 COPS7B CPNE1 CPZ CRLF3 CYTL1 DCAF16 DIP2B DIS3L2 DISP2 DOT1L EBPL EFEMP1 EIF1AD EIF2AK4 EPB41L1 ERC1 EVI2A FAM53A FLI1 FOXO3 GCHFR GFAP GGT7 GLB1 GRK4 GSTP1 HLX HM13 HORMAD2 IPO8 ISCA2 JAG1 JAZF1 LIN28B LLGL2 LRRC37A2 LRRC37A4P LTBP1 MAP1LC3A MAPT MCM4 MRPS35 MRPS6 MST1P2 NDUFB2 NDUFB2-AS1 NFAT5 NOB1 NOL8 NOP58 NR3C1 P4HA2 PARK7 PBLD PDIK1L PIBF1 PIEZO1 PROSER2 PSMC5 PTCH1 PYCR1 QSOX2 RAB7L1 RBBP8 RMI1 RP11-171I2.2 RP11-477D19.2 RP11-529H20.5 RP11-860B13.1 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 RRP15 SAMD4A SCMH1 SDCCAG3 SEMA3B-AS1 SENP6 SF3B2 SMAD3 SMPD2 SMURF2 SNAI3-AS1 SNUPN SNX13 STRA13 SUSD5 TBC1D30 TMTC4 TRAF3IP1 TSEN2 TULP4 UBXN2A UQCC WFIKKN1 WNT4 ZBTB4 ZNF641
Exposure to tobacco smoke at home 1.0 1 0 0.0 0.00 1.0e+00 RNF123
Tense / 'highly strung' 1.2 2 0 0.0 0.00 1.0e+00 SEMA3B-AS1 STX1B
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2 1 2.2 0.00 1.0e+00 CCDC87 TCF4
Hair/balding pattern: Pattern 4 2.5 14 8 17.8 0.41 1.2e-01 ARL17B C10orf11 C2orf42 CCDC46 CENPW CTB-36H16.2 DIP2B IQCH LRRC37A2 LRRC37A4P MAPT SMG6 SUPT3H TWIST1
Birth weight of first child 1.7 10 4 8.9 0.73 4.4e-03 ANAPC10 CTC-228N24.3 DCAF16 DCXR DLG4 FKBP5 HKDC1 IPO8 SLC12A2 WNT4
Peak expiratory flow (PEF) 2.8 36 21 46.7 0.64 9.4e-06 ABO ANAPC10 ARL17B ASPSCR1 BMP4 BOK C10orf11 C1GALT1 CAMK1D CCDC87 CDC123 CTA-85E5.10 CYTL1 DCAF16 EFEMP1 FAM53A HTR4 LRRC37A2 LRRC37A4P MAP1LC3A MAPT MDM4 MRPS21 NR2F1 PSMC5 PYCR1 RNF123 RP4-614O4.11 RPS6KA1 SF3B2 SMPD2 SSH2 TCF21 TMEM194B TNFAIP8 UQCC
Qualifications: O levels/GCSEs or equivalent 1.2 1 0 0.0 0.00 1.0e+00 DISP2
Blood clot in the leg (DVT) 1.4 1 1 2.2 0.00 1.0e+00 ABO
Medication: Paracetamol 1.5 4 3 6.7 -1.00 3.6e-04 LRRC37A2 LRRC37A4P MAPT MLLT10
Headache pain in last month 1.6 6 6 13.3 -0.76 1.8e-02 AFF1 ARL17B LRRC37A2 LRRC37A4P MAPT MRPS21
Medication for cholesterol, blood pressure or diabetes 1.3 3 1 2.2 0.00 1.0e+00 OPRL1 SIDT2 TCF21
Gout (self-reported) 1.2 2 0 0.0 0.00 1.0e+00 MUC1 NFAT5
Hypothyroidism/myxoedema (self-reported) 1.1 5 4 8.9 -0.99 4.8e-04 C6orf217 FKBP5 HORMAD2 SUOX TMEM194B
Medication: Amlodipine 1.3 1 0 0.0 0.00 1.0e+00 CHRNB1
Medication: Ventolin 100micrograms inhaler 1.3 1 0 0.0 0.00 1.0e+00 AAGAB
Birth weight 1.7 8 5 11.1 0.38 3.5e-01 ANAPC10 DCAF16 DLG4 FKBP5 HKDC1 HORMAD2 PTCH1 TULP4
Chronic bronchitis/emphysema (mother) 1.4 1 1 2.2 0.00 1.0e+00 CHRNA3
High blood pressure (siblings) 1.3 1 0 0.0 0.00 1.0e+00 STX1B
Forced vital capacity (FVC), Best measure 5.5 143 87 193.3 0.91 1.3e-64 AAGAB ABO AC073834.3 AC104532.4 ANAPC10 ANGPTL1 AOC1 AP3B1 AP4E1 ARFGEF2 ARID3B ARID5B ARL17B ARMS2 ASPSCR1 BANF1 BCDIN3D BMF BOK BRAF BTBD1 C10orf11 C2orf42 C2orf54 C6orf217 CARF CCDC126 CCDC171 CCDC87 CDC123 CENPW CEP120 CHCHD1 CHRNA3 CLIC6 CLUAP1 COG4 CPE CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTSS CUL3 DARS DCAF16 DCXR EBPL EEF1G EFEMP1 EIF1AD EIF2AK4 EPB41L1 EPB41L2 ERC1 EYA2 FKBP5 FOXN2 FOXP1 GFAP GOLGA6L9 GRK4 HORMAD2 HTR4 INTS12 IPO8 IQCH JAG1 LMCD1 LONRF2 LRPAP1 LRRC37A2 LRRC37A4P LTBP4 MAPT MCM6 MDM4 METTL22 MICAL3 MLLT10 MRPL21 MRPS35 MST1P2 MUC1 NDUFB2 NDUFB2-AS1 NFAT5 NLRC3 NNT NOB1 NOP58 NOX4 PDIK1L PKDCC PNMT PPARD PPIAL4C PRDM11 PSMC5 PTCH1 PYCR1 PYGB QSOX2 RAB3IL1 RAVER1 RIN3 RNF123 RP11-250B2.6 RP1-137D17.1 RP11-422P24.10 RP11-613D13.5 RP11-64K12.8 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 RRP15 SCMH1 SF3B2 SHROOM3 SLC12A2 SLC25A21 SLC2A4RG SMG7 SMPD2 SMURF2 SNAI3-AS1 SNUPN SSH2 STMN3 STX1B SUOX SUSD5 TBC1D30 TCP11L1 THBS2 TULP4 UBXN2A UQCC WDR18 WNT4 ZCCHC24 ZMAT2 ZNF438
Body fat percentage 2.1 47 33 73.3 -0.48 2.1e-04 AAGAB AC016725.4 AC073834.3 AIP AP3B1 ARFGEF2 C18orf8 C6orf106 CCDC171 CDK5RAP3 CENPW CHRNB1 CTC-228N24.3 CTSS DARS DCAF16 EIF3C FKBP5 FOXO3 FOXP1 GRK4 GSTP1 HOXC6 HTR4 IQCH KIAA1598 LCT LIME1 LRRC37A2 MAP2K5 MCM6 MLLT10 NFAT5 NOB1 PPARD PSMC5 PYGB RIN3 RNF123 RP11-613D13.5 RP1-283E3.4 SLC2A4RG SMAD3 SSH2 ST7L STX1B SYT14
Leg fat percentage (right) 2.2 43 27 60.0 -0.58 8.0e-06 AAGAB AC016725.4 AC073834.3 ARFGEF2 C18orf8 C6orf106 CARF CCDC171 CENPW CTC-228N24.3 DARS DCAF16 DLG4 EIF3C FKBP5 FOXN2 FOXP1 GRK4 HTR4 IQCH KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NOB1 PPARD PSMC5 PYGB RIN3 RNF123 RP11-613D13.5 RP1-283E3.4 RP4-614O4.11 SLC12A2 SLC2A4RG SNAI3-AS1 SNUPN SSH2 STX1B SYT14 UQCC
Arm fat-free mass (right) 2.7 71 50 111.1 -0.30 9.3e-03 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 HORMAD2 IPO8 JAZF1 MAP1LC3A MLLT10 MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC25A5P1 SMPD2 SNUPN SNX13 STX1B SUOX TBC1D30 UBXN2A UQCC ZBTB4
Comparative body size at age 10 1.5 16 9 20.0 0.11 6.9e-01 AP3B1 ATP6V0D1 BANF1 BCDIN3D CLUAP1 DOT1L EIF3C EVI2A IQCH LIN28B MAP2K5 SEMA3B-AS1 SMG6 ST7L STX1B ZNF641
Worry too long after embarrassment 1.4 5 1 2.2 -0.66 1.6e-01 BCDIN3D IQCH LRRC37A4P MAPT SYT14
Wheeze or whistling in the chest in last year 1.6 7 1 2.2 -0.95 1.2e-03 BTBD7 CCDC171 CCDC46 RNF123 SLC2A4RG STMN3 STX1B
Age at first live birth 1.3 3 1 2.2 0.00 1.0e+00 JMJD1C KIAA1598 RNF123
Health satisfaction 1.1 1 0 0.0 0.00 1.0e+00 RNF123
Qualifications: College or University degree 1.4 19 15 33.3 0.63 2.3e-03 BCDIN3D C11orf80 C18orf8 CLUAP1 CTSF DPP3 EIF3C FOXO3 FOXP1 GRK4 JMJD1C LRRC37A2 LRRC37A4P MAPT MDM4 RIN1 RNF123 STMN3 SUOX
Mouth/teeth dental problems: Loose teeth 1.3 2 2 4.4 0.99 1.1e-03 CCDC91 RP11-967K21.1
Medication for pain relief, constipation, heartburn 1.3 4 2 4.4 0.97 5.1e-03 LRRC37A2 LRRC37A4P MAPT PPARD
Medication: Blood pressure 1.4 2 0 0.0 0.00 1.0e+00 DLG4 TCF21
Angina (self-reported) 1.3 2 1 2.2 0.00 1.0e+00 GGT7 TCF21
Medication: Ibuprofen 1.1 1 0 0.0 0.00 1.0e+00 MAPT
Medication: Allopurinol 1.2 1 1 2.2 0.00 1.0e+00 MUC1
Mean time to correctly identify matches 1.3 8 2 4.4 -0.58 9.8e-02 ARFGEF2 ARL17B C11orf80 DLG4 FOXO3 RMI1 TOM1L2 WFIKKN1
Whole body fat mass 2.0 42 30 66.7 -0.50 2.8e-04 AAGAB AC016725.4 AIP ANAPC10 AP3B1 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CTD-2201E18.3 EFEMP1 EIF3C EPB41L1 FKBP5 FOXO3 FOXP1 GGT7 GRK4 GSTP1 HTR4 IQCH KIAA1598 LCT MAP1LC3A MAP2K5 MCM6 MLLT10 NFAT5 NOB1 NR3C1 PPARD PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SLC2A4RG SMAD3 SSH2 STX1B SYT14 UQCC
Leg fat mass (right) 1.8 33 23 51.1 -0.53 5.9e-04 AAGAB AC016725.4 AIP AP3B1 C18orf8 C6orf106 CCDC171 CDK5RAP3 CTC-228N24.3 CTD-2201E18.3 EIF3C FKBP5 FOXO3 FOXP1 GGT7 GRK4 HTR4 IQCH KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NOB1 PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SLC2A4RG SSH2 STX1B SYT14
Arm predicted mass (right) 2.7 68 52 115.6 -0.32 5.4e-03 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 B3GNT7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 HORMAD2 JAZF1 MAP1LC3A MLLT10 MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC25A5P1 SMPD2 SNUPN SNX13 STX1B SUOX UBXN2A UQCC ZBTB4
Pulse rate, automated reading 1.4 14 9 20.0 -0.41 1.1e-01 B3GNT7 BTBD1 C6orf106 CD55 CEP120 DARS EEF1G EIF2AK4 MSH6 NFAT5 PDIK1L TCF21 TMEM194B TOM1L2
Alcohol intake frequency. 1.5 14 9 20.0 -0.65 9.0e-03 ADH1B C18orf8 CDADC1 EIF3C EVI2A FOXP1 LEAP2 LRRC37A2 LRRC37A4P MAPT NFAT5 NOA1 SMPD2 TCF4
Comparative height size at age 10 3.4 90 67 148.9 -0.12 2.3e-01 AAGAB AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ARMS2 ATOH7 B3GNT7 BANF1 BCDIN3D BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC126 CCDC91 CENPW CEP120 CHRNB1 CHRNG CLUAP1 CNIH4 CNTROB COPS7B CPE CPNE1 CRLF3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FLI1 FOXO3 GGT7 HKDC1 HORMAD2 IQCH JAZF1 LRRC37A2 LRRC37A4P MAP1LC3A MAPT MICAL3 MRPS6 MST1P2 NR3C1 P4HA2 PBLD PDIK1L PIEZO1 PPIAL4C PSMC5 PTCH1 PYCR1 QSOX2 RAB7L1 RAVER1 RBBP8 RMI1 RP11-171I2.2 RP11-477D19.2 RP11-529H20.5 RP11-967K21.1 RP1-199J3.5 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SMPD2 SUSD5 TCF4 TRAF3IP1 TULP4 UBXN2A UQCC WFIKKN1 WNT4 WWOX ZBTB4
Suffer from 'nerves' 1.2 1 0 0.0 0.00 1.0e+00 EIF3C
Overall health rating 1.4 7 4 8.9 -0.96 7.9e-04 CCDC87 DCAF16 FOXP1 GRK4 HTR4 RNF123 STX1B
Age at last live birth 1.0 1 1 2.2 0.00 1.0e+00 RNF123
Knee pain experienced in last month 1.4 3 1 2.2 0.86 1.4e-01 FAM53A STX1B UQCC
Hypertension (Self-reported) 1.5 11 5 11.1 -0.34 3.1e-01 CHRNB1 DCAF16 DLG4 GCHFR HOXC6 HTR4 MAP2K5 NAT15 OPRL1 SLC12A2 STX1B
Illnesses of father: Heart disease 1.2 1 0 0.0 0.00 1.0e+00 TCF21
Illnesses of siblings: Diabetes 1.2 1 1 2.2 0.00 1.0e+00 CAMK1D
Smoking status: Previous 1.6 1 1 2.2 0.09 9.1e-01 MSH6
Forced expiratory volume in 1-second (FEV1), predicted 2.6 31 24 53.3 -0.45 7.9e-03 ANAPC10 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CHRNB1 CNIH4 CRLF3 DCAF16 DIS3L2 DOT1L EFEMP1 EPB41L1 GGT7 JAZF1 LIN28B LTBP1 MAP1LC3A MST1P2 PTCH1 RP11-529H20.5 RP11-967K21.1 RP4-614O4.11 SCMH1 SEMA3B-AS1 UQCC ZBTB4
Whole body fat-free mass 2.9 78 63 140.0 -0.19 8.7e-02 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 B3GNT7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 HORMAD2 IPO8 JAZF1 KIAA1598 MAP1LC3A MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 QSOX2 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC12A2 SLC25A5P1 SMPD2 SNAI3-AS1 SNUPN STX1B SUOX TULP4 UBXN2A UQCC WNT4 ZBTB4 ZMAT2
Leg fat-free mass (right) 2.7 72 48 106.7 -0.13 2.7e-01 AC062029.1 ACTG1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CDK5RAP3 CENPW CEP120 CHRNB1 CLUAP1 CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 GLB1 HORMAD2 IPO8 IQCH KIAA1598 MAP1LC3A MRPL21 MUC1 NR2F1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-90P5.2 RP11-967K21.1 RP4-614O4.11 RPS20 SCMH1 SLC12A2 SMPD2 SMURF2 SNAI3-AS1 STX1B SUOX SUPT3H TULP4 UQCC WNT4 ZSWIM7
Arm fat percentage (left) 1.9 39 29 64.4 -0.36 1.4e-02 AAGAB ABO AC016725.4 AP3B1 ARFGEF2 C17orf82 C18orf8 C6orf106 CCDC171 CCDC87 CDK5RAP3 CENPW CHRNB1 DCAF16 DLG4 EIF3C FKBP5 FOXP1 GRK4 HTR4 IQCH KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NOB1 NOP58 PPARD PYGB RNF123 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 SMAD3 SSH2 STX1B SYT14
Average weekly red wine intake 1.3 4 2 4.4 0.99 1.2e-02 C18orf8 CTSF FOXP1 SLC29A2
Handedness (chirality/laterality): Left-handed 1.5 5 4 8.9 0.79 3.4e-02 ARL17B LRRC37A2 LRRC37A4P MAP2 MAPT
Mood swings 1.5 7 6 13.3 -0.87 4.4e-03 ARL17B DCC LRRC37A2 LRRC37A4P MAPT RNF123 TCF4
Long-standing illness, disability or infirmity 1.7 5 1 2.2 -0.43 4.0e-01 CCDC171 IQCH NFAT5 NR2F1 RNF123
Diabetes diagnosed by doctor 1.6 4 3 6.7 -0.99 6.0e-03 CAMK1D JAZF1 NFAT5 ZCCHC24
Mouth/teeth dental problems: Mouth ulcers 1.3 4 3 6.7 -0.76 1.3e-01 CTSS LRRC37A2 LRRC37A4P MAPT
Back pain experienced in last month 1.4 3 1 2.2 0.00 1.0e+00 ARMS2 C6orf106 SMAD3
Asthma (self-reported) 1.7 11 8 17.8 0.01 9.8e-01 AAGAB C6orf217 HTR4 IQCH MAP2K5 P4HA2 PNMT RIN3 SLC2A4RG STMN3 SUOX
Osteoarthritis (self-reported) 1.3 2 0 0.0 0.00 1.0e+00 FAM53A RAVER1
Smoking status: Current 1.3 1 0 0.0 0.00 1.0e+00 STMN3
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.8 46 25 55.6 0.96 1.6e-29 ALDH6A1 ANGPTL1 ARL17B ASPSCR1 BMP6 BTBD1 C10orf11 CAMK1D CCDC91 CDC123 CEP120 CHCHD1 CHRNA3 CTA-85E5.10 CTSS DISP2 EEF1G GOLGA6L9 HM13 HTR4 INTS12 JAG1 LLGL2 LRRC37A2 LRRC37A4P MAP2 MAPT MICAL3 NNT NOB1 PDIK1L PLAGL2 PNMT PYGB QSOX2 RIN3 RNF123 RP11-541N10.3 RP11-967K21.1 SLC2A4RG SLMAP SOGA2 STMN3 STX1B UQCC WNT4
Whole body water mass 2.9 78 64 142.2 -0.18 9.3e-02 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 B3GNT7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 HORMAD2 IPO8 KIAA1598 MAP1LC3A MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 QSOX2 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC12A2 SLC25A5P1 SMPD2 SNAI3-AS1 SNUPN SNX13 STX1B SUOX TULP4 UBXN2A UQCC WNT4 ZBTB4 ZMAT2
Leg predicted mass (right) 2.7 72 48 106.7 -0.13 2.7e-01 AC062029.1 ACTG1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CDK5RAP3 CENPW CEP120 CHRNB1 CLUAP1 CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 GLB1 HORMAD2 IPO8 IQCH KIAA1598 MAP1LC3A MRPL21 MUC1 NR2F1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-90P5.2 RP11-967K21.1 RP4-614O4.11 RPS20 SCMH1 SLC12A2 SMPD2 SMURF2 SNAI3-AS1 STX1B SUOX SUPT3H TULP4 UQCC WNT4 ZSWIM7
Arm fat mass (left) 1.8 38 24 53.3 -0.57 7.0e-05 AAGAB AC016725.4 AP3B1 BTBD7 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CLUAP1 DLG4 EIF3C EPB41L1 FOXO3 FOXP1 GGT7 GRK4 HTR4 IQCH KIAA1598 LCT MAP1LC3A MAP2K5 MCM6 MLLT10 NFAT5 NLRC3 NOB1 NR2F1 PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SMAD3 STX1B SYT14 UQCC ZSWIM7
Number of self-reported non-cancer illnesses 1.7 8 4 8.9 0.04 9.0e-01 AAGAB CCDC87 IQCH MAP2K5 NFAT5 OPRL1 RNF123 STMN3
Average weekly champagne plus white wine intake 1.2 3 0 0.0 0.00 1.0e+00 LRRC37A2 LRRC37A4P MAPT
Miserableness 1.3 5 5 11.1 -0.94 5.4e-03 LRRC37A2 LRRC37A4P MAPT RNF123 TCF4
Guilty feelings 1.4 5 2 4.4 -0.77 7.5e-02 LIN28B LRRC37A2 LRRC37A4P MAPT UBXN2A
Financial situation satisfaction 1.1 1 0 0.0 0.00 1.0e+00 RNF123
Medication: Blood pressure 1.4 6 0 0.0 0.70 1.2e-01 C1GALT1 HOXC6 LRRC37A2 LRRC37A4P MAPT P4HA2
Supplements: Fish oil (including cod liver oil) 1.3 2 0 0.0 0.00 1.0e+00 CCDC87 NFAT5
High cholesterol (Self-reported) 1.5 7 5 11.1 -0.74 5.6e-02 ABO APOC1P1 CARF NOP58 OPRL1 SIDT2 TSEN2
Medication: Bendroflumethiazide 1.3 1 0 0.0 0.00 1.0e+00 TCF21
Medication: Paracetamol 1.4 3 3 6.7 -1.00 1.3e-03 LRRC37A2 LRRC37A4P MAPT
Ever smoked 1.5 2 1 2.2 0.08 9.0e-01 MSH6 ZFHX3
Basal metabolic rate 2.7 74 55 122.2 -0.25 2.7e-02 AC004540.4 AC062029.1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CDK5RAP3 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 CTC-228N24.3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 HORMAD2 IPO8 IQCH KIAA1598 MAP1LC3A MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 SCMH1 SDCCAG3 SENP6 SLC12A2 SLC25A5P1 SMPD2 STX1B SUOX TULP4 UBXN2A UQCC WNT4 ZBTB4 ZMAT2
Leg fat percentage (left) 2.2 44 27 60.0 -0.60 3.7e-06 AAGAB AC016725.4 AC073834.3 AIP ARFGEF2 C18orf8 C6orf106 CARF CCDC171 CENPW CTC-228N24.3 DARS DCAF16 EIF3C FKBP5 FOXN2 FOXO3 FOXP1 GRK4 HTR4 IQCH KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NOB1 PPARD PSMC5 PYGB RIN3 RNF123 RP11-613D13.5 RP1-283E3.4 RP4-614O4.11 SLC12A2 SLC2A4RG SSH2 STMN3 STX1B SYT14 UQCC ZCCHC24
Arm fat-free mass (left) 2.7 67 52 115.6 -0.32 6.4e-03 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 DCAF16 DIS3L2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GGT7 HORMAD2 KIAA1598 MAP1LC3A MLLT10 MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 RPS6KA1 SCMH1 SDCCAG3 SENP6 SLC25A5P1 SMPD2 SNX13 STX1B SUOX UBXN2A UQCC ZBTB4
Number of operations (self-reported) 1.5 3 0 0.0 0.00 1.0e+00 CTC-228N24.3 MLLT10 PARK7
Average weekly beer plus cider intake 1.2 2 0 0.0 0.00 1.0e+00 JMJD1C RNF123
Irritability 1.4 4 3 6.7 -0.99 7.6e-04 KLRAQ1 LRRC37A2 LRRC37A4P MAPT
Fractured/broken bones in last 5 years 1.4 1 0 0.0 0.00 1.0e+00 IQCH
Diastolic blood pressure, automated reading 1.4 21 10 22.2 -0.39 8.1e-02 ABO AC016725.4 ADAMTS8 CEP120 DARS DCAF16 DLG4 GCHFR JAG1 LIME1 MICAL3 RNF123 RP11-23P13.7 SCMH1 SLC2A4RG SLMAP SMG6 STMN3 STX1B THBS2 TMEM194B
Myopia 1.3 2 1 2.2 0.00 1.0e+00 BMP4 QSOX2
Vascular/heart problems diagnosed by doctor 1.4 11 6 13.3 0.29 3.8e-01 C1GALT1 CHRNB1 DCAF16 DLG4 GCHFR HOXC6 IQCH MAP2K5 OPRL1 STX1B TCF21
Cholesterol lowering medication 1.4 5 0 0.0 -0.99 1.7e-03 ABO CARF OPRL1 SIDT2 STX1B
Pain experienced in last month 1.4 2 0 0.0 0.00 1.0e+00 CENPW STX1B
Heart attack/myocardial infarction (self-reported) 1.2 2 0 0.0 0.00 1.0e+00 TCF21 TOM1L2
Deep venous thrombosis (DVT) (self-reported) 1.4 1 1 2.2 0.00 1.0e+00 ABO
Pack years of smoking 1.6 2 1 2.2 0.00 1.0e+00 CHRNA3 JMJD1C
Impedance of whole body 1.9 58 44 97.8 -0.10 4.4e-01 AOC1 ARL17B C11orf80 C6orf106 CENPW CEP120 CERS2 CLUAP1 CPNE1 CTC-228N24.3 CTSF CTSS DIP2B DPP3 EEF1G EFEMP1 EPB41L1 EVI2A FLJ12825 FOXO3 GGT7 HLX HOXC6 JAZF1 JMJD1C JPH2 LIME1 LIN28B LRRC37A2 LRRC37A4P LRRN2 LTBP1 MAP1LC3A MAPT MRPL21 MST1P2 MUC1 NLRC3 NOL8 NUFIP2 PIAS1 PNMAL1 PSMC5 RAVER1 RIN1 RIN3 RMI1 RNF123 RPS20 SCMH1 SEMA3B-AS1 SLC12A2 SLC2A4RG STX1B SUOX SUPT3H UQCC ZNF641
Leg fat mass (left) 1.8 36 23 51.1 -0.56 1.2e-04 AAGAB AC016725.4 AIP AP3B1 BTBD7 C18orf8 C6orf106 CCDC171 CDK5RAP3 CTC-228N24.3 CTD-2201E18.3 DARS EIF3C FKBP5 FOXO3 FOXP1 GGT7 GRK4 GSTP1 HTR4 IQCH KIAA1598 LCT MAP2K5 MCM6 MLLT10 NFAT5 NOB1 PYGB RNF123 RP11-613D13.5 RP1-283E3.4 SLC2A4RG SSH2 STX1B SYT14
Arm predicted mass (left) 2.6 67 51 113.3 -0.30 1.0e-02 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATOH7 BMP6 BOK C17orf82 C18orf8 C6orf106 CCDC91 CENPW CEP120 CHP CHRNB1 CHRNG CNIH4 COPS7B CPNE1 CRLF3 DCAF16 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EPB41L1 EVI2A FAM53A FOXO3 GFAP GGT7 HORMAD2 KIAA1598 MAP1LC3A MLLT10 MRPL21 MUC1 NR3C1 P4HA2 PARK7 PBLD PDIK1L PNMAL1 PSMC5 PTCH1 RAB7L1 RAVER1 RIN3 RNF123 RP11-613D13.5 RP11-967K21.1 RP4-614O4.11 RPS20 SCMH1 SDCCAG3 SENP6 SLC25A5P1 SMPD2 SNUPN STX1B SUOX UBXN2A UQCC ZBTB4 ZMAT2

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 104 3.0 5.1
GTEx Adipose Visceral Omentum 71 3.5 5.7
GTEx Adrenal Gland 52 3.6 5.6
GTEx Artery Aorta 102 3.4 5.7
GTEx Artery Coronary 45 3.8 6.4
GTEx Artery Tibial 111 3.0 5.2
GTEx Brain Caudate basal ganglia 30 3.3 5.6
GTEx Brain Cerebellar Hemisphere 51 3.4 6.1
GTEx Brain Cerebellum 75 3.8 5.7
GTEx Brain Cortex 39 3.8 5.9
GTEx Brain Frontal Cortex BA9 26 2.8 5.8
GTEx Brain Hippocampus 17 3.2 6.7
GTEx Brain Hypothalamus 20 3.4 6.3
GTEx Brain Nucleus accumbens basal ganglia 27 3.1 5.9
GTEx Brain Putamen basal ganglia 14 2.2 5.9
GTEx Breast Mammary Tissue 64 3.2 5.7
GTEx Breast Mammary Tissue (Male) 34 2.8 6.0
GTEx Breast Mammary Tissue (Female) 46 2.8 5.3
GTEx Cells EBV-transformed lymphocytes 43 3.0 5.9
GTEx Cells Transformed fibroblasts 143 3.4 5.3
GTEx Colon Sigmoid 34 2.3 5.6
GTEx Colon Transverse 62 3.0 5.6
GTEx Esophagus Gastroesophageal Junction 50 3.5 6.0
GTEx Esophagus Mucosa 116 3.5 5.4
GTEx Esophagus Muscularis 125 3.9 5.8
GTEx Heart Atrial Appendage 60 3.8 6.3
GTEx Heart Left Ventricle 59 3.9 5.7
GTEx Liver 28 3.9 5.9
GTEx Lung 100 3.5 5.6
GTEx Muscle Skeletal 100 3.5 5.4
GTEx Nerve Tibial 142 3.3 5.2
GTEx Ovary 40 4.4 7.0
GTEx Pancreas 51 3.1 5.6
GTEx Pituitary 49 4.4 6.3
GTEx Prostate 26 3.1 5.7
GTEx Skin Not Sun Exposed Suprapubic 78 3.2 5.7
GTEx Skin Sun Exposed Lower leg 128 3.5 5.5
GTEx Small Intestine Terminal Ileum 20 4.3 6.3
GTEx Spleen 55 3.9 5.9
GTEx Stomach 55 3.8 6.0
GTEx Testis 106 3.4 5.3
GTEx Thyroid 143 3.6 5.5
GTEx Uterus 25 4.4 7.1
GTEx Vagina 19 3.0 6.2
GTEx Whole Blood 60 3.0 5.2
METSIM Adipose 108 2.3 4.4
NTR Blood 61 2.5 4.5
ROSMAP Brain Pre-frontal Cortex 101 2.3 4.2
YFS Blood 141 3.1 4.4
CommonMind Brain Pre-frontal Cortex 112 2.1 4.3
The Cancer Genome Atlas Bladder Urothelial Carcinoma 49 3.0 4.7
The Cancer Genome Atlas Breast Invasive Carcinoma 120 2.7 4.5
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 29 2.6 4.7
The Cancer Genome Atlas Colon Adenocarcinoma 57 2.8 4.3
The Cancer Genome Atlas Esophageal Carcinoma 20 2.9 5.2
The Cancer Genome Atlas Glioblastoma Multiforme 34 3.3 5.1
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 83 3.0 4.6
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 93 2.3 4.4
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 45 2.2 4.4
The Cancer Genome Atlas Brain Lower Grade Glioma 115 2.7 4.4
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 37 3.3 5.0
The Cancer Genome Atlas Lung Adenocarcinoma 90 3.1 4.7
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 77 3.1 4.7
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 46 2.9 4.8
The Cancer Genome Atlas Pancreatic Adenocarcinoma 49 2.9 4.8
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 34 2.6 4.7
The Cancer Genome Atlas Prostate Adenocarcinoma 132 2.8 4.6
The Cancer Genome Atlas Rectum Adenocarcinoma 20 2.9 4.9
The Cancer Genome Atlas Soft Tissue Sarcoma 37 3.5 5.0
The Cancer Genome Atlas Skin Cutaneous Melanoma 23 4.3 5.3
The Cancer Genome Atlas Stomach Adenocarcinoma 50 3.0 4.8
The Cancer Genome Atlas Testicular Germ Cell Tumors 40 3.1 4.4
The Cancer Genome Atlas Thyroid Carcinoma 140 2.7 4.5
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 19 3.7 5.3