Best TWAS P=7.77e-15 · Best GWAS P=1.3e-13 conditioned to 0.394
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | TTC39B | 0.29 | 0.24 | enet | 38 | 0.24 | 2.0e-16 | -7.3 | -6.8 | 1.2e-11 | 0.83 | 0 | 1.00 | FALSE |
2 | GTEx | Lung | TTC39B | 0.18 | 0.17 | enet | 9 | 0.20 | 3.6e-15 | -7.3 | -7.8 | 7.8e-15 | 0.91 | 0 | 1.00 | TRUE |
3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TTC39B | 0.05 | 0.01 | blup | 146 | 0.02 | 5.3e-03 | -7.4 | -5.5 | 4.6e-08 | 0.59 | 0 | 0.98 | FALSE |
4 | The Cancer Genome Atlas | Lung Adenocarcinoma | TTC39B | 0.06 | 0.03 | enet | 10 | 0.03 | 3.3e-04 | -7.3 | -6.4 | 1.4e-10 | 0.78 | 0 | 0.99 | FALSE |